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-
- 18 August 2010 - Cat Genome Browser Available
+ 20 August 2010 -
+New ENCODE Integrated Regulation Super-track Released
+
+ We are pleased to announce the release of the ENCODE Integrated
+ Regulation super-track, a collection of regulatory tracks containing
+ state-of-the-art information about the mechanisms that turn genes on and
+ off at the transcription level. Individual tracks within the set show
+ enrichment of histone modifications suggestive of enhancer and promoter
+ activity, DNAse clusters indicating open chromatin, regions of
+ transcription factor binding, and transcription levels. When viewed in
+ combination, the complementary nature of the data within these tracks
+ has the potential to greatly facilitate our understanding of regulatory
+ DNA.
- We have released a Genome Browser for the latest assembly of Cat (Felis catus).
- The GTB V17E assembly (December 2008, UCSC version felCat4) was produced by the NHGRI
- Genome Technology Branch and NIH Intramural Sequencing Center, Maryland; Agencourt
- Bioscience Corporation, Massachusetts; NCI Laboratory of Genomic Diversity, Maryland;
- and Hill's Pet Nutrition, Inc, Kansas. The mitochondrial genome was sequenced by NCI
- Laboratory of Genomic Diversity. For detailed sequencing and assembly information, see
- the NCBI Felis catus
- assembly page.
-
-
-
- Downloads of the Cat data and annotations may be obtained from the
- UCSC FTP site
- or
- Downloads
- page. These data have been freely provided for use in the UCSC Genome Browser
- with specific conditions for use.
-
-
-
- Many thanks to NHGRI, Agencourt Bioscience Corporation, NCI and Hill's Pet Nutrition
- for providing these data. The felCat4 annotation tracks were generated by UCSC and
- its collaborators. We'd also like to acknowledge the UCSC Cat browser team: Chin Li,
- Antonio Coelho, Mary Goldman and Donna Karolchik. See the
- Credits
- page for a detailed list of the organizations and individuals who contributed to
- this release.
-
-
-
+
+ The data comprising these tracks were generated from hundreds of
+ experiments on multiple cell lines conducted by labs participating in
+ the Encyclopedia of DNA Elements (ENCODE) project, and were submitted to
+ the UCSC ENCODE Data Coordination Center for display on the Genome
+ Browser.
+
+
+ Faced with the problem of how to display such a large amount of data
+ in a manner facilitating analysis, UCSC has developed new visualization
+ methods that cluster and overlay the data, and then display the
+ resulting tracks on a single screen. Each of the cell lines in a track
+ is associated with a particular color. Light, saturated colors are used
+ to produce the best transparent overlay.
+
+
+  |
+
+
+ The data in the ENCODE Regulation super-track, as with all data from the
+ production phase of the ENCODE project, have genome-wide coverage. In
+ general, Genome Browser tracks that show ENCODE-generated data can be
+ identified by the double-helix icon preceding the name in the track
+ list. Currently, the ENCODE Regulation data are available only on the
+ March 2006 (NCBI Build 36, UCSC version hg18) assembly of the human
+ genome.
+
+
+ For a detailed description of the datasets contained in this super-track
+ and a discussion of how the tracks can be used synergistically to
+ examine regions of regulatory functionality within the genome, see the
+ track description page.
-
- 23 July 2010 - BigBed/BigWig Paper Published:
- We are pleased to announce that we have published a paper on the BigBed and BigWig
- format. Read more.
-
- Kent WJ, Zweig AS, Barber G, Hinrichs AS, Karolchik D.
- BigWig and BigBed: enabling browsing of large distributed data sets.
- Bioinformatics. 2010 July 17. Published online in advance of print.
-
-
+ 18 August 2010 -
+Cat Genome Browser Available:
+ We have released a Genome Browser for the latest assembly of Cat (Felis catus).
+ Read more.
-
- 15 July 2010 - Conservation
- track available for zebrafish (danRer6):
- We are pleased to announce the release of a new Conservation track based
- on the zebrafish (danRer6) assembly.
- Read more.
+ 23 July 2010 - BigBed/BigWig Paper Published:
+ We are pleased to announce that we have published a paper on
+ the BigBed and BigWig format.
+ Read more.
+ Kent WJ et al. BigWig and BigBed: enabling browsing of
+ large distributed data sets. Bioinformatics.
+ 2010 July 17. Published online in advance of print.
|