423772af6e63fd93b062a3fb2e58151e92ca5bd1
angie
Thu Sep 20 10:23:21 2012 -0700
Track #8886 (Denisova high-cov): Added composite track from Denisovaanalysis: sites where humans have a derived allele relative to chimp,
gorilla, and/or orangutan, and Denisova had the ancestral allele;
plus VEP annotations of predicted functional consequence.
diff --git src/hg/lib/dhcHumDerDenAnc.as src/hg/lib/dhcHumDerDenAnc.as
new file mode 100644
index 0000000..5258a38
--- /dev/null
+++ src/hg/lib/dhcHumDerDenAnc.as
@@ -0,0 +1,27 @@
+table dhcHumDerDenAnc
+"Human Derived, Denisova Ancestral variants and functional effect predictions from high-coverage Denisova sequencing project"
+ (
+ string chrom; "Reference sequence chromosome"
+ uint chromStart; "Start position in chromosome"
+ uint chromEnd; "End position in chromosome"
+ string name; "Human allele / Denisova ancestral allele"
+ string feature; "Ensembl Transcript ID or Regulatory Region ID
or ID of TFB profile from JASPAR or TRANSFAC"
+ string gene; "Ensembl Gene ID"
+ string extra; "Extra info: for coding genes, Ensembl Protein ID and/or HGNC;
for Regulatory Motifs, scores & matrix ID"
+ string consequence; "Variant Effect Predictor (VEP) consequence term"
+ string cdnaPosition; "Offset in transcript, if applicable"
+ string cdsPosition; "Offset in coding sequence (CDS), if applicable"
+ string protPosition; "Offset in protein sequence, if applicable"
+ string aminoAcids; "Amino acid change, if applicable"
+ string codons; "Codon change, if applicable"
+ string humanAl; "Modern human fixed (or major) allele on positive strand"
+ string denAl; "Denisova (ancestral) allele"
+ string chimpAl; "Chimpanzee ancestral allele"
+ string gorAl; "Gorilla ancestral allele"
+ string orangAl; "Orangutan ancestral allele"
+ string denZyg; "Denisova zygosity of ancestral allele (homozygous/heterozygous)"
+ string dbSNP; "dbSNP rs ID, if available"
+ float tgpFreq; "1000 Genomes Project frequency of modern human allele"
+ string flag; "Flag(s): CpG if in CpG island; RM if in repeat masked region;
LowQual if conflicting GATK calls; SysErr if prone to systematic errors"
+ char geneStrand; "Gene strand: '+' or '-', if applicable; otherwise '.'"
+ )