e70152e44cc66cc599ff6b699eb8adc07f3e656a kent Sat May 24 21:09:34 2014 -0700 Adding Copyright NNNN Regents of the University of California to all files I believe with reasonable certainty were developed under UCSC employ or as part of Genome Browser copyright assignment. diff --git src/hg/hgGene/domains.c src/hg/hgGene/domains.c index 89bff51..d73cdb2 100644 --- src/hg/hgGene/domains.c +++ src/hg/hgGene/domains.c @@ -1,240 +1,243 @@ /* domains - do protein domains section. */ +/* Copyright (C) 2014 The Regents of the University of California + * See README in this or parent directory for licensing information. */ + #include "common.h" #include "trashDir.h" #include "hash.h" #include "linefile.h" #include "dystring.h" #include "spDb.h" #include "hgGene.h" #include "hdb.h" #include "lsSnpPdbChimera.h" static boolean domainsExists(struct section *section, struct sqlConnection *conn, char *geneId) /* Return TRUE if there's some pfam domains in swissProt on this one. * on this one. */ { return swissProtAcc != NULL; } void modBaseAnchor(char *swissProtAcc) /* Print out anchor to modBase. */ { hPrintf("<A HREF=\"http://salilab.org/modbase/search?databaseID=%s\" TARGET=_blank>", swissProtAcc); //hPrintf("<A HREF=\"http://salilab.org/modbase-cgi/model_search.cgi?searchkw=name&kword=%s\" TARGET=_blank>", swissProtAcc); } static void domainsPrint(struct section *section, struct sqlConnection *conn, char *geneId) /* Print out protein domains. */ { char *db = sqlGetDatabase(conn); struct slName *el, *list; list = spExtDbAcc1List(spConn, swissProtAcc, "Interpro"); if (list != NULL) { char query[256], **row, **row2; struct sqlResult *sr, *sr2; hPrintf("<B>InterPro Domains: </B> "); hPrintf("<A HREF=\"http://www.ebi.ac.uk/interpro/protein/%s\" TARGET=_blank>", swissProtAcc); hPrintf("Graphical view of domain structure</A><BR>"); sqlSafef(query, sizeof(query), "select extAcc1,extAcc2 from extDbRef,extDb" " where extDbRef.acc = '%s'" " and extDb.val = 'Interpro' and extDb.id = extDbRef.extDb" , swissProtAcc); sr = sqlGetResult(spConn, query); while ((row = sqlNextRow(sr)) != NULL) { //hPrintf("<A HREF=\"http://www.ebi.ac.uk/interpro/entry/%s\" TARGET=_blank>", row[0]); //hPrintf("%s</A> - %s<BR>\n", row[0], row[1]); char interPro[256]; char *pdb = hPdbFromGdb(db); safef(interPro, 128, "%s.interProXref", pdb); if (hTableExists(db, interPro)) { sqlSafef(query, sizeof(query), "select description from %s where accession = '%s' and interProId = '%s'", interPro, swissProtAcc, row[0]); sr2 = sqlGetResult(conn, query); if ((row2 = sqlNextRow(sr2)) != NULL) { hPrintf("<A HREF=\"http://www.ebi.ac.uk/interpro/entry/%s\" TARGET=_blank>", row[0]); hPrintf("%s</A> - %s <BR>\n", row[0], row2[0]); } sqlFreeResult(&sr2); } else { hPrintf("<A HREF=\"http://www.ebi.ac.uk/interpro/entry/%s\" TARGET=_blank>", row[0]); hPrintf("%s</A> - %s<BR>\n", row[0], row[1]); } } hPrintf("<BR>\n"); slFreeList(&list); } if (kgVersion == KG_III) { /* Do Pfam domains here. */ list = getPfamDomainList(conn, geneId); if (list != NULL) { hPrintf("<B>Pfam Domains:</B><BR>"); for (el = list; el != NULL; el = el->next) { char query[256]; char *description; sqlSafef(query, sizeof(query), "select description from pfamDesc where pfamAC='%s'", el->name); description = sqlQuickString(conn, query); if (description == NULL) description = cloneString("n/a"); hPrintf("<A HREF=\"http://pfam.sanger.ac.uk/family?acc=%s\" TARGET=_blank>", el->name); hPrintf("%s</A> - %s<BR>\n", el->name, description); freez(&description); } slFreeList(&list); hPrintf("<BR>\n"); } /* Do SCOP domains here */ list = getDomainList(conn, geneId, "Scop"); if (list != NULL) { hPrintf("<B>SCOP Domains:</B><BR>"); for (el = list; el != NULL; el = el->next) { char query[256]; char *description; sqlSafef(query, sizeof(query), "select description from scopDesc where acc='%s'", el->name); description = sqlQuickString(conn, query); if (description == NULL) description = cloneString("n/a"); hPrintf("<A HREF=\"http://scop.berkeley.edu/sunid=%s\" TARGET=_blank>", el->name); hPrintf("%s</A> - %s<BR>\n", el->name, description); freez(&description); } slFreeList(&list); hPrintf("<BR>\n"); } } else { list = spExtDbAcc1List(spConn, swissProtAcc, "Pfam"); if (list != NULL) { char *pfamDescSql = genomeSetting("pfamDescSql"); hPrintf("<B>Pfam Domains:</B><BR>"); for (el = list; el != NULL; el = el->next) { char query[256]; char *description; sqlSafef(query, sizeof(query), pfamDescSql, el->name); description = sqlQuickString(conn, query); if (description == NULL) description = cloneString("n/a"); hPrintf("<A HREF=\"http://pfam.sanger.ac.uk/family?acc=%s\" TARGET=_blank>", el->name); hPrintf("%s</A> - %s<BR>\n", el->name, description); freez(&description); } slFreeList(&list); hPrintf("<BR>\n"); } } list = spExtDbAcc1List(spConn, swissProtAcc, "PDB"); if (list != NULL) { struct sqlConnection *conn2 = sqlConnect(db); char query[256], **row; struct sqlResult *sr; int column = 0, maxColumn=3, rowCount=0; hPrintf("<B>Protein Data Bank (PDB) 3-D Structure</B><BR>"); sqlSafef(query, sizeof(query), "select extAcc1,extAcc2 from extDbRef,extDb" " where extDbRef.acc = '%s'" " and extDb.val = 'PDB' and extDb.id = extDbRef.extDb" , swissProtAcc); sr = sqlGetResult(spConn, query); hPrintf("<TABLE><TR>\n"); while ((row = sqlNextRow(sr)) != NULL) { if (++column > maxColumn) { hPrintf("</TR><TR>"); column = 1; if (rowCount == 0) { hPrintf("<TD ALIGN=CENTER COLSPAN=4><I>To conserve bandwidth, only the images from the first %d structures are shown.</I>", maxColumn); hPrintf("</TR><TR>"); } ++rowCount; } hPrintf("<TD>"); hPrintf("<A HREF=\"http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=%s\" TARGET=_blank>", row[0]); if (rowCount < 1) hPrintf("<IMG SRC=\"http://www.rcsb.org/pdb/images/%s_asym_r_250.jpe\"><BR>", row[0]); hPrintf("%s</A> - %s ", row[0], row[1]); // include links LS-SNP and to launch viewer in PDB chimera struct tempName chimerax; lsSnpPdbChimeraSnpAnn(conn, row[0], NULL, &chimerax); hPrintf(" <A HREF=\"%s\">Chimera</A>", chimerax.forHtml); if (lsSnpPdbHasPdb(conn2, row[0])) hPrintf(" <A HREF=\"%s\" TARGET=_blank>LS-SNP</A>", lsSnpPdbGetUrlPdbSnp(row[0], NULL)); hPrintf("</TD>\n"); } hPrintf("</TR></TABLE>\n"); hPrintf("<A href=\"../goldenPath/help/chimera.html\" TARGET=_blank>Chimera help</A>\n"); hPrintf("<BR><BR>\n"); slFreeList(&list); sqlDisconnect(&conn2); } /* Do modBase link. */ { hPrintf("<B>ModBase Predicted Comparative 3D Structure on "); modBaseAnchor(swissProtAcc); hPrintf("%s", swissProtAcc); hPrintf("</A></B><BR>\n"); hPrintf("<TABLE><TR>"); hPrintf("<TD>"); modBaseAnchor(swissProtAcc); hPrintf("\n<IMG SRC=\"http://salilab.org/modbaseimages/image/modbase.jpg?database_id=%s\"></A></TD>", swissProtAcc); hPrintf("<TD>"); modBaseAnchor(swissProtAcc); hPrintf("\n<IMG SRC=\"http://salilab.org/modbaseimages/image/modbase.jpg?database_id=%s&axis=x°ree=90\"></A></TD>", swissProtAcc); hPrintf("<TD>"); modBaseAnchor(swissProtAcc); hPrintf("\n<IMG SRC=\"http://salilab.org/modbaseimages/image/modbase.jpg?database_id=%s&axis=y°ree=90\"></A></TD>", swissProtAcc); hPrintf("</TR><TR>\n"); hPrintf("<TD ALIGN=CENTER>Front</TD>"); hPrintf("<TD ALIGN=CENTER>Top</TD>"); hPrintf("<TD ALIGN=CENTER>Side</TD>"); hPrintf("</TR></TABLE>\n"); hPrintf("<I>The pictures above may be empty if there is no " "ModBase structure for the protein. The ModBase structure " "frequently covers just a fragment of the protein. You may " "be asked to log onto ModBase the first time you click on the " "pictures. It is simplest after logging in to just click on " "the picture again to get to the specific info on that model.</I>"); } } struct section *domainsSection(struct sqlConnection *conn, struct hash *sectionRa) /* Create domains section. */ { struct section *section = sectionNew(sectionRa, "domains"); section->exists = domainsExists; section->print = domainsPrint; return section; }