fbe9faf925e4fbcb5366c86d821be064a1b56872
kate
Wed Jul 22 17:03:47 2015 -0700
Add faint gray line under graph to show extent when bars are missing. refs #15645
diff --git src/hg/hgTracks/gtexTracks.c src/hg/hgTracks/gtexTracks.c
index 5f22dc8..d54fb51 100644
--- src/hg/hgTracks/gtexTracks.c
+++ src/hg/hgTracks/gtexTracks.c
@@ -1,397 +1,400 @@
/* GTEX tracks */
/* Copyright (C) 2015 The Regents of the University of California
* See README in this or parent directory for licensing information. */
#include "common.h"
#include "hgTracks.h"
#include "hvGfx.h"
#include "rainbow.h"
#include "gtexGeneBed.h"
#include "gtexTissue.h"
#include "gtexUi.h"
#define WIN_MAX_GRAPH 20000
#define MAX_GRAPH_HEIGHT 100
#define MAX_BAR_WIDTH 5
#define MAX_GRAPH_PADDING 2
#define WIN_MED_GRAPH 500000
#define MED_GRAPH_HEIGHT 60
#define MED_BAR_WIDTH 3
#define MED_GRAPH_PADDING 1
#define MIN_GRAPH_HEIGHT 20
#define MIN_BAR_WIDTH 1
#define MIN_GRAPH_PADDING 0
#define MARGIN_WIDTH 1
//#define GENCODE_CODING_COLOR 0x0c0c78 // rgb(12,12,120)
//#define GENCODE_NONCODING_COLOR 0x006400 // rgb(0,100,0)
//#define GENCODE_PROBLEM_COLOR 0xfe000 //rgb(254,0,0)
#define GENCODE_CODING_COLOR "12,12,120"
#define GENCODE_NONCODING_COLOR "0,100,0"
#define GENCODE_PROBLEM_COLOR "254,0,0"
#define UNKNOWN_COLOR "1,1,1"
static struct statusColors
{
Color coding;
Color nonCoding;
Color problem;
Color unknown;
} statusColors = {0,0,0};
static int findColorIx(struct hvGfx *hvg, char *rgb)
{
unsigned char red, green, blue;
parseColor(rgb, &red, &green, &blue);
return (hvGfxFindColorIx(hvg, red, green, blue));
//return MAKECOLOR_32(red, green, blue);
}
static void initGeneColors(struct hvGfx *hvg)
{
if (statusColors.coding != 0)
return;
statusColors.coding = findColorIx(hvg, GENCODE_CODING_COLOR);
statusColors.nonCoding = findColorIx(hvg, GENCODE_NONCODING_COLOR);
statusColors.problem = findColorIx(hvg, GENCODE_PROBLEM_COLOR);
statusColors.unknown = findColorIx(hvg, UNKNOWN_COLOR);
}
static int gtexBarWidth()
{
int winSize = winEnd - winStart;
if (winSize < WIN_MAX_GRAPH)
return MAX_BAR_WIDTH;
else if (winSize < WIN_MED_GRAPH)
return MED_BAR_WIDTH;
else
return MIN_BAR_WIDTH;
}
static int gtexGraphPadding()
{
int winSize = winEnd - winStart;
if (winSize < WIN_MAX_GRAPH)
return MAX_GRAPH_PADDING;
else if (winSize < WIN_MED_GRAPH)
return MED_GRAPH_PADDING;
else
return MIN_GRAPH_PADDING;
}
static int gtexGraphHeight()
{
int winSize = winEnd - winStart;
if (winSize < WIN_MAX_GRAPH)
return MAX_GRAPH_HEIGHT;
else if (winSize < WIN_MED_GRAPH)
return MED_GRAPH_HEIGHT;
else
return MIN_GRAPH_HEIGHT;
}
+static int gtexGraphWidth(struct gtexGeneBed *gtex)
+/* Width of GTEx graph in pixels */
+{
+int barWidth = gtexBarWidth();
+int padding = gtexGraphPadding();
+int count = gtex->expCount;
+return (barWidth * count) + (padding * (count-1));
+}
+
static int valToY(double val, double maxVal, int height)
/* Convert a value from 0 to maxVal to 0 to height-1 */
{
double scaled = val/maxVal;
int y = scaled * (height);
return (height-1) - y;
//int y = scaled * (height-1);
//return (height - 1) - y;
}
struct gtexGeneExtras
{
double maxExp;
};
/* Cache tissue metadata */
struct gtexTissue *getGtexTissues()
/* Get tissue metadata from database */
{
static struct gtexTissue *gtexTissues = NULL;
if (gtexTissues == NULL)
{
char query[1024];
struct sqlConnection *conn = sqlConnect("hgFixed");
sqlSafef(query, sizeof(query), "select * from gtexTissue order by id");
gtexTissues = gtexTissueLoadByQuery(conn, query);
}
return gtexTissues;
}
struct rgbColor *getGtexTissueColors()
/* Get RGB colors from tissue table */
{
struct gtexTissue *tissues = getGtexTissues();
struct gtexTissue *tissue = NULL;
int count = slCount(tissues);
struct rgbColor *colors;
AllocArray(colors, count);
int i = 0;
for (tissue = tissues; tissue != NULL; tissue = tissue->next)
{
// TODO: reconcile
colors[i] = (struct rgbColor){.r=COLOR_32_BLUE(tissue->color), .g=COLOR_32_GREEN(tissue->color), .b=COLOR_32_RED(tissue->color)};
//colors[i] = mgColorIxToRgb(NULL, tissue->color);
i++;
}
return colors;
}
-#ifdef NEW
-static int gtexGraphWidth(struct gtexGeneBed *gtex)
-/* Width of GTEx graph in pixels */
-{
-int barWidth = gtexBarWidth();
-int padding = gtexGraphPadding();
-int count = gtex->expCount;
-return (barWidth * count) + (padding * (count-1));
-}
-#endif
-
static int gtexGraphX(struct gtexGeneBed *gtex)
/* Locate graph on X, relative to viewport. Return -1 if it won't fit */
{
int start = max(gtex->chromStart, winStart);
//int end = min(gtex->chromEnd, winEnd);
//if (start > end)
//return -1;
double scale = scaleForWindow(insideWidth, winStart, winEnd);
int x1 = round((start - winStart) * scale);
//int x2 = round((end - winStart) * scale);
//int width = gtexGraphWidth(gtex);
//if (x1 + width > x2)
//return -1;
return x1;
}
static int gtexGeneHeight()
{
return 8;
}
static int gtexGeneMargin()
{
return 1;
}
static void gtexGeneDrawAt(struct track *tg, void *item, struct hvGfx *hvg, int xOff, int y,
double scale, MgFont *font, Color color, enum trackVisibility vis)
{
struct gtexGeneBed *geneBed = item;
initGeneColors(hvg);
//warn("item: %s, xOff=%d\n", geneBed->name, xOff);
// Color using transcriptClass
Color statusColor;
if (geneBed->transcriptClass == NULL)
statusColor = statusColors.unknown;
else if (sameString(geneBed->transcriptClass, "coding"))
statusColor = statusColors.coding;
else if (sameString(geneBed->transcriptClass, "nonCoding"))
statusColor = statusColors.nonCoding;
else if (sameString(geneBed->transcriptClass, "problem"))
statusColor = statusColors.problem;
else
statusColor = statusColors.unknown;
if (vis != tvFull && vis != tvPack)
{
bedDrawSimpleAt(tg, item, hvg, xOff, y, scale, font, statusColor, vis);
return;
}
int i;
int expCount = geneBed->expCount;
double maxExp = ((struct gtexGeneExtras *)tg->extraUiData)->maxExp;
struct rgbColor lineColor = {.r=0};
int lineColorIx = hvGfxFindColorIx(hvg, lineColor.r, lineColor.g, lineColor.b);
int heightPer = tg->heightPer;
int graphX = gtexGraphX(geneBed);
if (graphX < 0)
return;
// x1 is at left of graph
int x1 = xOff + graphX;
// yZero is at bottom of graph
int yZero = gtexGraphHeight() + y - 1;
-uglyf("DRAW: xOff=%d, x1=%d, y=%d, yZero=%d
", xOff, x1, y, yZero);
+// draw faint line under graph to delineate extent when bars are missing (tissue w/ 0 expression)
+Color lightGray = MAKECOLOR_32(0xD1, 0xD1, 0xD1);
+hvGfxBox(hvg, x1, yZero+1, gtexGraphWidth(geneBed), 1, lightGray);
+
+//uglyf("DRAW: xOff=%d, x1=%d, y=%d, yZero=%d
", xOff, x1, y, yZero);
int barWidth = gtexBarWidth();
int graphPadding = gtexGraphPadding();
char *colorScheme = cartUsualStringClosestToHome(cart, tg->tdb, FALSE, GTEX_COLORS,
GTEX_COLORS_DEFAULT);
struct rgbColor *colors;
if (sameString(colorScheme, GTEX_COLORS_GTEX))
{
// retrieve from table
// TODO: cache this
colors = getGtexTissueColors();
}
else
{
// currently the only other choice
// TODO: cache this
colors = getRainbow(&saturatedRainbowAtPos, expCount);
//colors = getRainbow(&lightRainbowAtPos, expCount);
}
for (i=0; iexpScores[i];
int yMedian = valToY(expScore, maxExp, gtexGraphHeight()) + y;
//int height = yZero - yMedian + 1;
int height = yZero - yMedian;
// TODO: adjust yGene instead of yMedian+1 to get gene track distance as desired
//if (i ==0) uglyf("DRAW: expScore=%.2f, maxExp=%.2f, graphHeight=%d, y=%d
", expScore, maxExp, gtexGraphHeight(), y);
- if (i ==0) uglyf("DRAW: yZero=%d, yMedian=%d, height=%d
", yZero, yMedian, height);
+ //if (i ==0) uglyf("DRAW: yZero=%d, yMedian=%d, height=%d
", yZero, yMedian, height);
if (graphPadding == 0 || sameString(colorScheme, GTEX_COLORS_GTEX))
hvGfxBox(hvg, x1, yMedian+1, barWidth, height, fillColorIx);
else
hvGfxOutlinedBox(hvg, x1, yMedian+1, barWidth, height, fillColorIx, lineColorIx);
x1 = x1 + barWidth + graphPadding;
}
+
// mark gene extent
int yGene = yZero + gtexGeneMargin() - 1;
#ifdef NO_GENE
// underline
int start = max(geneBed->chromStart, winStart);
int end = min(geneBed->chromEnd, winEnd);
if (start > end)
return;
int xStart = round((start - winStart) * scale)+xOff;
int width = round((end-start)*scale);
hvGfxBox(hvg, xStart, yGene, width, gtexGeneHeight(), lineColorIx);
//uglyf("DRAW: xStart=%d, yGene=%d, width=%d, height=%d
", xStart, yGene, width, gtexGeneHeight());
#endif
// load & draw gene model
char query[1024];
char **row;
sqlSafef(query, sizeof query, "select * from gtexGeneModel where name='%s'", geneBed->geneId);
struct sqlConnection *conn = hAllocConn(database);
if (conn == NULL)
return;
-uglyf("query: %s
", query);
+//uglyf("query: %s
", query);
struct sqlResult *sr = sqlGetResult(conn, query);
struct genePred *geneModel = NULL;
if (sr != NULL)
{
if ((row = sqlNextRow(sr)) != NULL)
geneModel = genePredLoad(row);
sqlFreeResult(&sr);
}
if (geneModel == NULL)
return;
struct linkedFeatures *lf = linkedFeaturesFromGenePred(tg, geneModel, FALSE);
tg->heightPer = gtexGeneHeight()+1;
lf->filterColor = statusColor;
linkedFeaturesDrawAt(tg, lf, hvg, xOff, yGene, scale, font, color, tvSquish);
tg->heightPer = heightPer;
hFreeConn(&conn);
}
static void gtexGeneMapItem(struct track *tg, struct hvGfx *hvg, void *item, char *itemName,
char *mapItemName, int start, int end, int x, int y, int width, int height)
/* Create a map box for each tissue (bar in the graph) */
{
-uglyf("map item: itemName=%s, mapItemName=%s, start=%d, end=%d, x=%d, y=%d, width=%d, height=%d, insideX=%d
",
- itemName, mapItemName, start, end, x, y, width, height, insideX);
+//uglyf("map item: itemName=%s, mapItemName=%s, start=%d, end=%d, x=%d, y=%d, width=%d, height=%d, insideX=%d
",
+ //itemName, mapItemName, start, end, x, y, width, height, insideX);
struct gtexTissue *tissues = getGtexTissues();
struct gtexTissue *tissue = NULL;
struct gtexGeneBed *gtex = item;
int barWidth = gtexBarWidth();
int padding = gtexGraphPadding();
double maxExp = ((struct gtexGeneExtras *)tg->extraUiData)->maxExp;
int graphX = gtexGraphX((struct gtexGeneBed *)item);
if (graphX < 0)
return;
// x1 is at left of graph
int x1 = insideX + graphX;
int i = 0;
int yZero = gtexGraphHeight() + y - 1;
for (tissue = tissues; tissue != NULL; tissue = tissue->next, i++)
{
double expScore = gtex->expScores[i];
int yMedian = valToY(expScore, maxExp, gtexGraphHeight()) + y;
int height = yZero - yMedian;
// TODO: call genericMapItem
//genericMapItem(tg, hvg, item, itemName, tissue->description, start, end, x1, y, barWidth, height);
mapBoxHc(hvg, start, end, x1, yMedian+1, barWidth, height, tg->track, mapItemName, tissue->description);
- if (i==0) uglyf("MAP: expScore=%.2f, maxExp=%.2f, graphHeight=%d, y=%d
", expScore, maxExp, gtexGraphHeight(), y);
- if (i==0) uglyf("MAP: x=%d, x1=%d, y=%d, yZero=%d
", x, x1, y, yZero);
- if (i==0) uglyf("MAP: yZero=%d, yMedian=%d, height=%d
", yZero, yMedian, height);
+ //if (i==0) uglyf("MAP: expScore=%.2f, maxExp=%.2f, graphHeight=%d, y=%d
", expScore, maxExp, gtexGraphHeight(), y);
+ //if (i==0) uglyf("MAP: x=%d, x1=%d, y=%d, yZero=%d
", x, x1, y, yZero);
+ //if (i==0) uglyf("MAP: yZero=%d, yMedian=%d, height=%d
", yZero, yMedian, height);
x1 = x1 + barWidth + padding;
}
}
static struct gtexGeneBed *loadGtexGeneBed(char **row)
{
return gtexGeneBedLoad(row);
}
static void gtexGeneLoadItems(struct track *track)
{
bedLoadItem(track, track->table, (ItemLoader)loadGtexGeneBed);
double maxExp = 0.0;
int i;
struct gtexGeneBed *geneBed;
for (geneBed = track->items; geneBed != NULL; geneBed = geneBed->next)
for (i=0; iexpCount; i++)
maxExp = (geneBed->expScores[i] > maxExp ? geneBed->expScores[i] : maxExp);
struct gtexGeneExtras *extras;
AllocVar(extras);
extras->maxExp = maxExp;
track->extraUiData = extras;
}
static int gtexGeneItemHeight(struct track *track, void *item)
{
if ((item == NULL) || (track->visibility == tvSquish) || (track->visibility == tvDense))
return 0;
return gtexGraphHeight() + + gtexGeneMargin() + gtexGeneHeight();
}
static int gtexTotalHeight(struct track *track, enum trackVisibility vis)
/* Figure out total height of track */
{
int height;
if (track->visibility == tvSquish || track->visibility == tvDense)
height = 10;
else
height = gtexGraphHeight() + gtexGeneMargin() + gtexGeneHeight();
return tgFixedTotalHeightOptionalOverflow(track, vis, height, height, FALSE);
}
void gtexGeneMethods(struct track *track)
{
track->drawItemAt = gtexGeneDrawAt;
track->loadItems = gtexGeneLoadItems;
track->mapItem = gtexGeneMapItem;
track->itemHeight = gtexGeneItemHeight;
track->totalHeight = gtexTotalHeight;
}