df66e5b7936616048e5503a03196ef1684a63a07 kate Wed Mar 16 12:07:50 2016 -0700 New schema for GTEX gene bed file. Removes bogus transcriptId and replaces transcriptClass with geneType. refs #15645 diff --git src/hg/lib/gtexGeneBed.c src/hg/lib/gtexGeneBed.c index 78e9239..02f773d 100644 --- src/hg/lib/gtexGeneBed.c +++ src/hg/lib/gtexGeneBed.c @@ -1,221 +1,252 @@ /* gtexGeneBed.c was originally generated by the autoSql program, which also * generated gtexGeneBed.h and gtexGeneBed.sql. This module links the database and * the RAM representation of objects. */ #include "common.h" #include "linefile.h" #include "dystring.h" #include "jksql.h" #include "gtexGeneBed.h" -char *gtexGeneBedCommaSepFieldNames = "chrom,chromStart,chromEnd,name,score,strand,geneId,transcriptId,transcriptClass,expCount,expScores"; +char *gtexGeneBedCommaSepFieldNames = "chrom,chromStart,chromEnd,name,score,strand,geneId,geneType,expCount,expScores"; + +struct gtexGeneBed *gtexGeneBedLoadByQuery(struct sqlConnection *conn, char *query) +/* Load all gtexGeneBed from table that satisfy the query given. + * Where query is of the form 'select * from example where something=something' + * or 'select example.* from example, anotherTable where example.something = + * anotherTable.something'. + * Dispose of this with gtexGeneBedFreeList(). */ +{ +struct gtexGeneBed *list = NULL, *el; +struct sqlResult *sr; +char **row; + +sr = sqlGetResult(conn, query); +while ((row = sqlNextRow(sr)) != NULL) + { + el = gtexGeneBedLoad(row); + slAddHead(&list, el); + } +slReverse(&list); +sqlFreeResult(&sr); +return list; +} + +void gtexGeneBedSaveToDb(struct sqlConnection *conn, struct gtexGeneBed *el, char *tableName, int updateSize) +/* Save gtexGeneBed as a row to the table specified by tableName. + * As blob fields may be arbitrary size updateSize specifies the approx size + * of a string that would contain the entire query. Arrays of native types are + * converted to comma separated strings and loaded as such, User defined types are + * inserted as NULL. This function automatically escapes quoted strings for mysql. */ +{ +struct dyString *update = newDyString(updateSize); +char *expScoresArray; +expScoresArray = sqlFloatArrayToString(el->expScores, el->expCount); +sqlDyStringPrintf(update, "insert into %s values ( '%s',%u,%u,'%s',%u,'%s','%s','%s',%u,'%s')", + tableName, el->chrom, el->chromStart, el->chromEnd, el->name, el->score, el->strand, el->geneId, el->geneType, el->expCount, expScoresArray ); +sqlUpdate(conn, update->string); +freeDyString(&update); +freez(&expScoresArray); +} struct gtexGeneBed *gtexGeneBedLoad(char **row) /* Load a gtexGeneBed from row fetched with select * from gtexGeneBed * from database. Dispose of this with gtexGeneBedFree(). */ { struct gtexGeneBed *ret; AllocVar(ret); -ret->expCount = sqlUnsigned(row[9]); +ret->expCount = sqlUnsigned(row[8]); ret->chrom = cloneString(row[0]); ret->chromStart = sqlUnsigned(row[1]); ret->chromEnd = sqlUnsigned(row[2]); ret->name = cloneString(row[3]); ret->score = sqlUnsigned(row[4]); safecpy(ret->strand, sizeof(ret->strand), row[5]); ret->geneId = cloneString(row[6]); -ret->transcriptId = cloneString(row[7]); -ret->transcriptClass = cloneString(row[8]); +ret->geneType = cloneString(row[7]); { int sizeOne; -sqlFloatDynamicArray(row[10], &ret->expScores, &sizeOne); +sqlFloatDynamicArray(row[9], &ret->expScores, &sizeOne); assert(sizeOne == ret->expCount); } return ret; } struct gtexGeneBed *gtexGeneBedLoadAll(char *fileName) /* Load all gtexGeneBed from a whitespace-separated file. * Dispose of this with gtexGeneBedFreeList(). */ { struct gtexGeneBed *list = NULL, *el; struct lineFile *lf = lineFileOpen(fileName, TRUE); -char *row[11]; +char *row[10]; while (lineFileRow(lf, row)) { el = gtexGeneBedLoad(row); slAddHead(&list, el); } lineFileClose(&lf); slReverse(&list); return list; } struct gtexGeneBed *gtexGeneBedLoadAllByChar(char *fileName, char chopper) /* Load all gtexGeneBed from a chopper separated file. * Dispose of this with gtexGeneBedFreeList(). */ { struct gtexGeneBed *list = NULL, *el; struct lineFile *lf = lineFileOpen(fileName, TRUE); -char *row[11]; +char *row[10]; while (lineFileNextCharRow(lf, chopper, row, ArraySize(row))) { el = gtexGeneBedLoad(row); slAddHead(&list, el); } lineFileClose(&lf); slReverse(&list); return list; } struct gtexGeneBed *gtexGeneBedCommaIn(char **pS, struct gtexGeneBed *ret) /* Create a gtexGeneBed out of a comma separated string. * This will fill in ret if non-null, otherwise will * return a new gtexGeneBed */ { char *s = *pS; if (ret == NULL) AllocVar(ret); ret->chrom = sqlStringComma(&s); ret->chromStart = sqlUnsignedComma(&s); ret->chromEnd = sqlUnsignedComma(&s); ret->name = sqlStringComma(&s); ret->score = sqlUnsignedComma(&s); sqlFixedStringComma(&s, ret->strand, sizeof(ret->strand)); ret->geneId = sqlStringComma(&s); -ret->transcriptId = sqlStringComma(&s); -ret->transcriptClass = sqlStringComma(&s); +ret->geneType = sqlStringComma(&s); ret->expCount = sqlUnsignedComma(&s); { int i; s = sqlEatChar(s, '{'); AllocArray(ret->expScores, ret->expCount); for (i=0; i<ret->expCount; ++i) { ret->expScores[i] = sqlFloatComma(&s); } s = sqlEatChar(s, '}'); s = sqlEatChar(s, ','); } *pS = s; return ret; } void gtexGeneBedFree(struct gtexGeneBed **pEl) /* Free a single dynamically allocated gtexGeneBed such as created * with gtexGeneBedLoad(). */ { struct gtexGeneBed *el; if ((el = *pEl) == NULL) return; freeMem(el->chrom); freeMem(el->name); freeMem(el->geneId); -freeMem(el->transcriptId); -freeMem(el->transcriptClass); +freeMem(el->geneType); freeMem(el->expScores); freez(pEl); } void gtexGeneBedFreeList(struct gtexGeneBed **pList) /* Free a list of dynamically allocated gtexGeneBed's */ { struct gtexGeneBed *el, *next; for (el = *pList; el != NULL; el = next) { next = el->next; gtexGeneBedFree(&el); } *pList = NULL; } void gtexGeneBedOutput(struct gtexGeneBed *el, FILE *f, char sep, char lastSep) /* Print out gtexGeneBed. Separate fields with sep. Follow last field with lastSep. */ { if (sep == ',') fputc('"',f); fprintf(f, "%s", el->chrom); if (sep == ',') fputc('"',f); fputc(sep,f); fprintf(f, "%u", el->chromStart); fputc(sep,f); fprintf(f, "%u", el->chromEnd); fputc(sep,f); if (sep == ',') fputc('"',f); fprintf(f, "%s", el->name); if (sep == ',') fputc('"',f); fputc(sep,f); fprintf(f, "%u", el->score); fputc(sep,f); if (sep == ',') fputc('"',f); fprintf(f, "%s", el->strand); if (sep == ',') fputc('"',f); fputc(sep,f); if (sep == ',') fputc('"',f); fprintf(f, "%s", el->geneId); if (sep == ',') fputc('"',f); fputc(sep,f); if (sep == ',') fputc('"',f); -fprintf(f, "%s", el->transcriptId); -if (sep == ',') fputc('"',f); -fputc(sep,f); -if (sep == ',') fputc('"',f); -fprintf(f, "%s", el->transcriptClass); +fprintf(f, "%s", el->geneType); if (sep == ',') fputc('"',f); fputc(sep,f); fprintf(f, "%u", el->expCount); fputc(sep,f); { int i; if (sep == ',') fputc('{',f); for (i=0; i<el->expCount; ++i) { fprintf(f, "%g", el->expScores[i]); fputc(',', f); } if (sep == ',') fputc('}',f); } fputc(lastSep,f); } /* -------------------------------- End autoSql Generated Code -------------------------------- */ void gtexGeneBedCreateTable(struct sqlConnection *conn, char *table) /* Create expression record format table of given name. */ { char query[1024]; sqlSafef(query, sizeof(query), "CREATE TABLE %s (\n" " chrom varchar(255) not null, # Reference sequence chromosome or scaffold\n" " chromStart int unsigned not null, # Start position in chromosome\n" " chromEnd int unsigned not null, # End position in chromosome\n" " name varchar(255) not null, # Gene symbol\n" " score int unsigned not null, # Score from 0-1000\n" " strand char(1) not null, # + or - for strand\n" " geneId varchar(255) not null, # Ensembl gene ID, referenced in GTEx data tables\n" -" transcriptId varchar(255) not null, # Ensembl ID of Canonical transcript; determines genomic position\n" -" transcriptClass varchar(255) not null, # GENCODE transcript class (coding, nonCoding, pseudo)\n" +" geneType varchar(255) not null, # GENCODE gene biotype\n" " expCount int unsigned not null, # Number of experiment values\n" " expScores longblob not null, # Comma separated list of experiment scores\n" "#Indices\n" " PRIMARY KEY(geneId)\n" ")\n", table); sqlRemakeTable(conn, table, query); } char *gtexVersionSuffix(char *table) /* Return version string for a GTEx track table. For now, just supporting V4 and V6 (default, no suffix )*/ { if (endsWith(table, "V4")) return("V4"); return(""); }