8661e8f2fc9a3dd45c75a4efe96c2cfa8676c958 ceisenhart Fri Aug 25 11:50:08 2017 -0700 Documentation for the COSMIC track update, refs #19932 diff --git src/hg/lib/cosmicNew.as src/hg/lib/cosmicNew.as index 51ce0b4..a7b3325 100644 --- src/hg/lib/cosmicNew.as +++ src/hg/lib/cosmicNew.as @@ -1,41 +1,44 @@ table cosmicNew "Bed representation of the Catalog of Somatic Mutations in Cancer (COSMIC)" ( string chrom; "Reference sequence chromosome or scaffold" uint chromStart; "Start position in chromosome" uint chromEnd; "End position in chromosome" string name; "COSMIC mutation ID" + uint score; "Unused. A score between 0 and 1000" char[1] strand; "+ or - for strand. Use . if not applicable" + uint thickStart; "Start position in chromosome" + uint thickEnd; "End position in chromosome" string geneName; "Gene: HUGO symbol, mir-* ID, etc" string transcriptAcc; "ENST, NM_, XM_ or other transcript accession" int geneCdsLength; "Length of the gene (base pair) counts" int geneId; "If gene is in HGNC, this id helps linking it to HGNC" string sampleName; "A sample is an instance of a portion of a tumour being examined for mutations" int sampleId; "A sample id is used to identify a sample within the COSMIC database" int idTumor; "A number of samples can be taken from a single tumour and a number of tumours can be obtained from one individual" string primSite; "Primary site of organ or tissue from which tumor sample was taken" string siteSubtype1; "Subtype 1 site of organ or tissue from which tumor sample was taken" string siteSubtype2; "Subtype 2 site of organ or tissue from which tumor sample was taken" string siteSubtype3; "Subtype 3 site of organ or tissue from which tumor sample was taken" string primHistology; "Primary histology of organ or tissue from which tumor sample was taken" string histSubtype1; "Subtype 1 histology of organ or tissue from which tumor sample was taken" string histSubtype2; "Subtype 2 histology of organ or tissue from which tumor sample was taken" string histSubtype3; "Subtype 3 histology of organ or tissue from which tumor sample was taken" lstring ntChange; "Nucleotide sequence change" lstring aaChange; "Amino acid sequence change" string mutDescription; "Description of effect of variant on gene" string mutZygosity; "Information on whether the mutation was reported to be homozygous , heterozygous or unknown within the sample" string loh; "LOH Information on whether the gene was reported to have loss of heterozygosity in the sample, yes, no or unknown." char[1] snp; "All the known SNPs are flagged as 'y' defined by the 1000 genomes project, dbSNP and a panel of 378 normal (non-cancer) samples from Sanger CGP sequencing" string resMut; "Resistant mutation, mutation confers drug resistance" string fathmmPred; "FATHMM (Functional Analysis through Hidden Markov Models) prediction" float fathmmScore; "FATHMM score, a pvalue ranging from 0 to 1. Greater than .5 is signicant, less is benign" string mutSomStat; "Mutation somatic status" int pubmedId; "The PUBMED id for the paper the sample was noted in" string studyIds; "Lists the unique Ids of studies that have involved this sample." string samSource; "Describes where the sample has originated from" string tumSource; "Describes the tumor type" float age; "Age of the sample (if provided)" string cosmLabel; "COSMIC external name" string _mouseOver; "Mouseover label" )