b84011815ab7d9c53d637875c56551bde573870b jnavarr5 Thu Jun 20 15:13:50 2019 -0700 Announcing the GDC Cancer track for hg38, refs #22742 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index 9253a81..360fa8e 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -39,30 +39,64 @@ </div> <div class="col-sm-3"> <ul> <li><a href="#2004">2004 News</a></li> <li><a href="#2003">2003 News</a></li> <li><a href="#2002">2002 News</a></li> <li><a href="#2001">2001 News</a></li> </ul> </div> </div> </div> <!-- ============= 2019 archived news ============= --> <a name="2019"></a> +<a name="062019"></a> +<h2> Jun. 20, 2019 New GDC Cancer variants track and lollipop display for human +(GRCh38/hg38)</h2> +<p> +We are pleased to announce the +<a href="../cgi-bin/hgTrackUi?db=hg38&position=chr1%3A11102837-11267747&g=gdcCancer" target="_blank"> +GDC Cancer mutations</a> track for human (<em>GRCh38/hg38</em>). This +track shows the genomic positions of somatic variants found through whole genome sequencing of +tumors as part of +<a href="https://www.cancer.gov/about-nci/organization/ccg/research/structural-genomics/tcga" +target="_blank">The Cancer Genome Atlas (TCGA)</a> by the National Cancer Institute, made available +through the <a href="https://portal.gdc.cancer.gov/" taret="_blank">Genomic Data Commons Portal</a>. +The data shown is sometimes called the "Pan-Cancer dataset", a collection of +thirty-three TCGA projects processed in a uniform way. +</p> +<p> +With the release of the GDC Cancer track, we are introducing a new lollipop display mode, available +when this track is in 'full' or 'squish' mode. These variants can be shown in two display +modes: +<ul> + <li>Lollipop Mode: variants are shown with circles, the y-axis represents the number of samples + within the cohort. (<em>Available in 'full' or 'squish' modes</em>.)</li> + <li>BED Mode: variants are shown as normal genomic features. + (<em>Available in 'pack' or 'dense' modes</em>.)</li> +</ul></p> +<p class="text-center"> + <img class='text-center' src="../images/gdcCancerLollipop.jpg" width='699' alt="GDC Cancer lollipop display"> +</p> +<p> +We would like to thank the <a href="https://portal.gdc.cancer.gov/" target="_blank">Genomic Data +Commons Portal</a> for making the TCGA data available on their web site. We would also like to thank +Brian Raney and Jairo Navarro at the UCSC Genome Browser for creating and testing this track and +the new lollipop display mode.</p> + <a name="061719"></a> <h2> Jun. 17, 2019 New ENCODE 3 transcription factor binding site track sets for human (<em>GRCh37/hg19, GRCh38/hg38</em>)</h2> <p> We are pleased to announce two new ENCODE 3 transcription factor binding site track sets for human (GRCh37/hg19, GRCh38/hg38). These track sets show regions of transcription factor binding derived from a large collection of ChIP-seq experiments performed by the ENCODE project between February 2011 and November 2018. </p> <p> The ENCODE TF ChIP-seq data were processed using the <a href="https://www.encodeproject.org/chip-seq/transcription_factor/" target="_blank" >ENCODE Transcription Factor ChIP-seq Processing Pipeline</a> to generate peaks of TF binding. Peaks from 1264 experiments (1256 in hg38) representing 338 transcription factors (340 in hg38) in