d9535c7a71dcab75772ae9e1bb900f1f32fbfd38 brianlee Thu Oct 10 16:10:09 2019 -0700 Adding group auto-scale setting announcement refs #3420 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index 1494bd0..d9a4c2d 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -39,30 +39,61 @@ </div> <div class="col-sm-3"> <ul> <li><a href="#2004">2004 News</a></li> <li><a href="#2003">2003 News</a></li> <li><a href="#2002">2002 News</a></li> <li><a href="#2001">2001 News</a></li> </ul> </div> </div> </div> <!-- ============= 2019 archived news ============= --> <a name="2019"></a> +<a name="101119"></a> +<h2>Oct. 11, 2019 New "group auto-scale" option</h2> +<p> +A new "group auto-scale" option is now available for signal tracks +collected together in composites. The original auto-scale setting, which is still +available, acts to auto-scale each track individually inside a composite group. +With the new "group auto-scale" setting, all of the tracks within the +composite will scale to the track with the highest auto-scale value viewed in the region.</p> +<p> +For example, below is a side-by-side image of two views of the same data from +a selection of cell lines within a composite of related RNA-seq experiments. On +the left is the original "auto-scale to data view" setting, where each track is +auto-scaled to appear at each track's highest value. And on the right is +the new "group auto-scale" setting for the same RNA-seq data where all tracks +are scaled against the one track that has the highest value (67215 for IMR9 cell TAP + 1) +in the region.</p> +<p class="text-center"> + <img class='text-center' src="../images/groupAutoScale.png" width='800' alt="Auto-scale comparison"> +</p> +<p> +While the original auto-scale setting on the left has the advantage of showing any +available data calibrated to each track's maximum, the new "group auto-scale" +setting on the right quickly draws attention to the track with the highest signal +within the composite group.</p> +<p> +The new "group auto-scale" setting can be found for signal tracks within a +composite under the "Data viewing scaling:" options. +<p class="text-center"> + <img class='text-center' src="../images/groupAutoSetting.png" width='800' alt="Scaling options"> +</p> + <a name="100919"></a> <h2>Oct. 9, 2019 Expanded CRISPR track released for human (hg38/GRCh38)</h2> <p> We are pleased to announce the release of an expanded <a href="../cgi-bin/hgTracks?db=hg38&hideTracks=1&knownGene=pack&crisprAllTargets=pack&position=chr7:116397500-116398000" target="_blank">CRISPR Targets track</a> for the human hg38/GRCh38 assembly. This track shows the DNA sequences targetable by CRISPR RNA guides using the Cas9 enzyme from S. pyogenes (PAM: NGG) over the entire human genome. CRISPR target sites were annotated with predicted specificity (off-target effects) and predicted efficiency (on-target cleavage) by various algorithms through the tool <a href="http://crispor.tefor.net/" target="_blank">CRISPOR</a>. The target sequence of the guide is shown with a thick (exon) bar. The PAM motif match (NGG) is shown with a thinner bar. </p> <p class="text-center"> <img class='text-center' src="../images/crisperAllTargetsHg38.png" width='800' alt="CrisprAllTargets track"> </p>