cde60ba0f1009a6bccbe1d0da148100dccd12468 ccpowell Tue Oct 8 14:49:50 2019 -0700 Releasing crisprAllTargets for hg38, refs #24172 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index ac1e76b..032b692 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -38,30 +38,51 @@ </ul> </div> <div class="col-sm-3"> <ul> <li><a href="#2004">2004 News</a></li> <li><a href="#2003">2003 News</a></li> <li><a href="#2002">2002 News</a></li> <li><a href="#2001">2001 News</a></li> </ul> </div> </div> </div> <!-- ============= 2019 archived news ============= --> <a name="2019"></a> + +<a name="100919"></a> +<h2>Oct. 9, 2019 Expanded CRISPR track released for human (hg38/GRCh38)</h2> +<p> +We are pleased to announce the release of an expanded + <a href="../cgi-bin/hgTracks?db=hg38&hideTracks=1&knownGene=pack&crisprAllTargets=pack&position=chr7:116397500-116398000" target="_blank">CRISPR Targets track</a> for the human +hg38/GRCh38 assembly. This track shows the DNA sequences targetable by CRISPR RNA guides +using the Cas9 enzyme from S. pyogenes (PAM: NGG) over the entire human genome. CRISPR target +sites were annotated with predicted specificity (off-target effects) and predicted efficiency +(on-target cleavage) by various algorithms through the tool +<a href="http://crispor.tefor.net/" target="_blank">CRISPOR</a>. The target sequence of the guide +is shown with a thick (exon) bar. The PAM motif match (NGG) is shown with a thinner bar. +</p> +<p class="text-center"> + <img class='text-center' src="../images/crisperAllTargetsHg38.png" width='850' alt="CrisprAllTargets track"> +</p> + +<p> +We would like to thank Maximilian Haeussler, Hiram Clawson, and Conner Powell for their effort +creating and releasing this data track.</p> + <a name="09172019"></a> <h2>Sep. 17, 2019 New GRC Incident track for Chicken (galGal6) and Zebrafish (danRer11) </h2> <p> We are pleased to announce the release of a GRC Incident track for both the Chicken (<a href="../cgi-bin/hgTrackUi?&db=galGal6&g=grcIncidentDb" target="_blank">galGal6</a>) and Zebrafish (<a href="../cgi-bin/hgTrackUi?&db=danRer11&g=grcIncidentDb" target="_blank">danRer11</a>) assemblies. These tracks show locations in the Chicken and Zebrafish assemblies where assembly problems have been noted or resolved, as reported by the <a href="https://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/index.shtml" target="_blank"> Genome Reference Consortium (GRC)</a>. <ul> <li> <a href="../cgi-bin/hgTracks?db=galGal6&hideTracks=1&grcIncidentDb=pack&refSeqComposite=squish&knownGene_sel=1&position=chr1%3A81414-19700000" target="_blank">Chicken (galGal6) GRC Incident Database track</a></li>