726a4c9c82592c662ae6b8c715e67b783c95beb3 angie Mon Nov 18 13:45:42 2019 -0800 Instead of dropping rs IDs that have incomplete frequency data, add two new ucscNotes: freqIncomplete and freqNotMapped. refs #23283 diff --git src/hg/lib/bigDbSnp.c src/hg/lib/bigDbSnp.c index 9fd0390..62b7548 100644 --- src/hg/lib/bigDbSnp.c +++ src/hg/lib/bigDbSnp.c @@ -319,33 +319,38 @@ "Variant is in ClinVar with reports of both benign and pathogenic significance." }, { bdsClinvarPathogenic, "Variant is in ClinVar with clinical significance of pathogenic and/or likely pathogenic." }, { bdsClusterError, "This variant has the same start, end and class as another variant; " "they probably should have been merged into one variant." }, { bdsCommonAll, "Variant is \"common\", i.e. has a Minor Allele Frequency of at least 1% " "in all projects reporting frequencies." }, { bdsCommonSome, "Variant is \"common\", i.e. has a Minor Allele Frequency of at least 1% " "in some, but not all, projects reporting frequencies." }, { bdsDiffMajor, "Different frequency sources have different major alleles " "(see table of allele frequencies above)." }, + { bdsFreqIncomplete, + "At least one project's frequency data is incomplete (only one allele reported)." }, { bdsFreqIsAmbiguous, "At least one allele reported by at least one project " "contains an IUPAC ambiguous base (e.g. 'R' for 'A or G')." }, + { bdsFreqNotMapped, + "At least one project reported frequencies on a different assembly, for which dbSNP does not " + "provide a mapping. The mapping on this assembly may have an issue." }, { bdsFreqNotRefAlt, "The reference genome allele is not the major allele in at least one project." }, { bdsMultiMap, "This variant has been mapped to more than one distinct genomic location." }, { bdsOtherMapErr, "Another mapping of this variant has illegal coordinates implying indel mapping error." }, { bdsOverlapDiffClass, "This variant overlaps another variant with a different type/class." }, { bdsOverlapSameClass, "This variant overlaps another with the same type/class but different start/end." }, { bdsRareAll, "Variant is \"rare\", i.e. has a Minor Allele Frequency of less than 1% " "in all projects reporting frequencies, or has no frequency data." }, { bdsRareSome, "Variant is \"rare\", i.e. has a Minor Allele Frequency of less than 1% "