+These tracks represent the experimentally validated promoters generated by +the Eukaryotic Promoter Database. +
+ ++Each item in the track is a representation of the promoter +sequence identified by EPD. +The "thin" part of the element represents the 49 bp upstream of the annotated transcription +start site (TSS) whereas the "thick" part represents the TSS plus +10 bp downstream. The relative position of the thick and thin parts +define the orientation of the promoter. +
++Note that the EPD team has created a +public track hub containing promoter and supporting annotations for human, mouse, +and other vertebrate and model organism genomes. +
+ ++For a description of the methodology and principles used by EPD to +predict TSSs, refer to Dreos et al. (2013) in the References +section below. A more detailed description of how this data was +generated can be found at the following links: + +
+Data was generated by the EPD team at the +Swiss Institute of Bioinformatics +For inquiries, contact the EPD team using this on-line form +or email + +philipp. +bucher@epfl. +ch + +. +
+ ++Dreos R, Ambrosini G, Perier RC, Bucher P. + +EPD and EPDnew, high-quality promoter resources in the +next-generation sequencing era. Nucleic Acids +Res. 2013 Jan 1;41(D1):D157-64. PMID: 23193273. +
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