9ee755e1977934400656229a22c6aaa369eb1c4e max Thu Dec 12 02:08:06 2019 -0800 adding a section gene FAQ, refs #24624 diff --git src/hg/htdocs/FAQ/FAQgenes.html src/hg/htdocs/FAQ/FAQgenes.html index 6fbc91b..8ade084 100755 --- src/hg/htdocs/FAQ/FAQgenes.html +++ src/hg/htdocs/FAQ/FAQgenes.html @@ -2,30 +2,31 @@ <!--#set var="TITLE" value="Genome Browser FAQ" --> <!--#set var="ROOT" value=".." --> <!-- Relative paths to support mirror sites with non-standard GB docs install --> <!--#include virtual="$ROOT/inc/gbPageStart.html" --> <h1>Frequently Asked Questions: Gene tracks</h1> <h2>Topics</h2> <ul> <li><a href="#gene">What is a gene?</a></li> <li><a href="#genestrans">What is a transcript and how is it related to a gene?</a></li> <li><a href="#genename">What is a gene name?</a></li> <li><a href="#mostCommon">What are the most common gene transcript tracks?</a></li> +<li><a href="#wrong">I think this transcript looks strange, what shall I do?</a></li> <li><a href="#ens">What are Ensembl and GENCODE and is there a difference?</a></li> <li><a href="#ensRefseq">What are the differences among GENCODE, Ensembl and RefSeq?</a></li> <li><a href="#hg19">For the human assembly hg19/GRCh37: What is the difference between "UCSC Genes" track, the "GENCODE" track and the "Ensembl Genes" track?</a></li> <li><a href="#hg38">For the human assembly hg38/GRCh38: What are the differences between the "GENCODE" and "All GENCODE" tracks?</a></li> <li><a href="#gencode">What is the difference between GENCODE comprehensive and basic?</a></li> <li><a href="#ncbiRefseq">What is the difference between "NCBI RefSeq" and "UCSC RefSeq"?</a></li> <li><a href="#report">How shall I report a gene transcript in a manuscript?</a></li> <li><a href="#ccds">What is CCDS?</a></li> <li><a href="#justsingle">How can I show a single transcript per gene?</a></li> <li><a href="#singledownload">How can I download a file with a single transcript per gene?</a></li> <li><a href="#whatdo">This is rather complicated. Can you tell me which gene transcript track I should use?</a></li> </ul> @@ -167,30 +168,41 @@ </tr> <tr> <td>UCSC RefSeq (Curated)</td> <td>80,694</td> </tr> <tr> <td>NCBI RefSeq Curated</td> <td>73,080</td> </tr> <tr> <td>CCDS</td> <td>32,506</td> </tr> </table> +<a name="wrong"></a> +<h6>I think this transcript looks strange, what shall I do?</h6> + +<p>The Genome Browser Group only displays transcripts provided by others. +But both RefSeq and Gencode have dedicated staff that look manually at each and every transcript and they +know everything there is to know about gene models. +They are happy to answer your questions and they can change the transcript annotation. Submit your questions +via the <a href="https://www.ncbi.nlm.nih.gov/projects/RefSeq/update.cgi" target=_blank>RefSeq contact form</a> +or the <a href="https://www.gencodegenes.org/pages/contact.html" target=_blank>Gencode context form.</a> +</p> + <a name="ens"></a> <h2>The differences</h2> Some of our gene tracks look similar and contain very similar information which can be confusing. <h6>What are Ensembl and GENCODE and is there a difference?</h6> <p> Officially, the Ensembl and GENCODE gene models are the same. On the latest human and mouse genome assemblies (hg38 and mm10), the identifiers, transcript sequences, and exon coordinates are almost identical between equivalent Ensembl and GENCODE versions (excluding <a target=_blank href="FAQdownloads.html#downloadAlt">alternative sequences</a> or <a target=_blank href="FAQdownloads.html#downloadFix">fix sequences</a>).</p>