+We are pleased to announce a new track, RefSeq Select+MANE, for the GRCh37/hg19 and GRCh38/hg38 +human assemblies. This track is a combination of NCBI transcripts with the RefSeq Select +tag, as well as transcripts with the MANE Select tag. The result is a track with a +single representative transcript for every protein-coding gene. The track can be +found as part of the NCBI RefSeq composite track.
++RefSeq Select +transcripts are chosen by an NCBI pipeline to be representative of every protein-coding +gene. As part of the MANE project, however, RefSeq +Select transcripts that have a 100% identical match to a transcript in the +Ensembl annotation are given the MANE Select designation. In this way, MANE Select +is a subset of RefSeq Select. It should be noted, however, that there are +cases where RefSeq Select transcripts are replaced when a different MANE Select +transcript is chosen. Once the MANE project is complete, RefSeq Select and MANE +Select for human should be nearly the same.
++In summary, this track provides a functional canonical gene set until the MANE +set is complete. More information on this track and data can be found in the track description page, +NCBI's RefSeq Select +page, and the MANE page.
++We would like to thank NCBI for releasing the RefSeq Select data, as well as the NCBI and +Ensembl-GENCODE collaboration for MANE. We would also like to thank Max Haussler and Lou +Nassar for the development and release of these tracks.
+We are pleased to announce new GENCODE Gene annotation tracks, which correspond to Ensembl 99, for three assemblies: hg19/GRCh37, hg38/GRCh38, and mm10/GRCm38. For human, the GENCODE V33 annotations were mapped to hg38/GRCh38 and then back-mapped to the hg19/GRCh37 assembly. For all three assemblies, the gene sets contain the following tracks: