72411c72feeb19cb6a06bab7089900c49119456d
lrnassar
  Wed Feb 26 11:33:47 2020 -0800
News release for RefSeq Select + MANE track refs #24787

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 <!-- ============= 2020 archived news ============= -->
 <a name="2020"></a>
 
+<a name="022720"></a>
+<h2>Feb. 27, 2020 &nbsp;&nbsp; New NCBI RefSeq Select + MANE track for Human (hg19/hg38)</h2>
+<p>
+We are pleased to announce a new track, RefSeq Select+MANE, for the <a target="_blank" 
+href="../../cgi-bin/hgTrackUi?db=hg19&c=chr1&g=refSeqComposite">GRCh37/hg19</a> and <a 
+target="_blank" href="../../cgi-bin/hgTrackUi?db=hg38&c=chr1&g=refSeqComposite">GRCh38/hg38</a> 
+human assemblies. This track is a combination of NCBI transcripts with the <em>RefSeq Select</em> 
+tag, as well as transcripts with the <em>MANE Select</em> tag. The result is a track with a 
+single representative transcript for every protein-coding gene. The track can be 
+found as part of the NCBI RefSeq composite track.</p>
+<p>
+<a target="_blank" href="https://www.ncbi.nlm.nih.gov/refseq/refseq_select/">RefSeq Select</a> 
+transcripts are chosen by an NCBI pipeline to be representative of every protein-coding 
+gene. As part of the <a target="_blank" 
+href="https://www.ncbi.nlm.nih.gov/refseq/MANE/">MANE project</a>, however, RefSeq 
+Select transcripts that have a 100% identical match to a transcript in the 
+Ensembl annotation are given the MANE Select designation. In this way, MANE Select 
+is a subset of RefSeq Select. It should be noted, however, that there are 
+cases where RefSeq Select transcripts are replaced when a different MANE Select 
+transcript is chosen. Once the MANE project is complete, RefSeq Select and MANE 
+Select for human should be nearly the same.</p>
+<p>
+In summary, this track provides a functional canonical gene set until the MANE 
+set is complete. More information on this track and data can be found in the <a target="_blank" 
+href="../../cgi-bin/hgTrackUi?db=hg19&c=chr1&g=refSeqComposite">track description page</a>, 
+NCBI's <a target="_blank" href="https://www.ncbi.nlm.nih.gov/refseq/refseq_select/">RefSeq Select 
+page</a>, and the <a target="_blank" href="https://www.ncbi.nlm.nih.gov/refseq/MANE/">MANE page</a>.</p>
+<p>
+We would like to thank NCBI for releasing the RefSeq Select data, as well as the NCBI and
+Ensembl-GENCODE collaboration for MANE. We would also like to thank Max Haussler and Lou 
+Nassar for the development and release of these tracks.</p>
+
 <a name="021120"></a>
 <h2>Feb. 11, 2020 &nbsp;&nbsp; New GENCODE gene tracks: Human V33 (hg19/hg38) - Mouse M24 
 (mm10)</h2>
 <p>
 We are pleased to announce new GENCODE Gene annotation tracks, which correspond
 to <a href="http://www.ensembl.info/2019/10/17/whats-coming-up-in-ensembl-release-99/"
 target="_blank">Ensembl 99</a>, for three assemblies: <a target="_blank" 
 href="../../cgi-bin/hgTrackUi?db=hg19&c=chr21&g=wgEncodeGencodeV33lift37">hg19/GRCh37</a>, 
 <a target="_blank" href="../../cgi-bin/hgTrackUi?db=hg38c=chr1&g=wgEncodeGencodeV33">hg38/GRCh38</a>, 
 and <a target="_blank" href="../../cgi-bin/hgTrackUi?db=mm10&c=chr12&g=wgEncodeGencodeVM24">mm10/GRCm38</a>.
 For human, the GENCODE V33 annotations were mapped to hg38/GRCh38 and then back-mapped 
 to the hg19/GRCh37 assembly. For all three assemblies, the gene sets contain the following 
 tracks:</p>
 <ul>
   <li>Basic - a subset of the <em>Comprehensive set</em>.</li>