6091558bab452de0ba020f3e08a9d20ef9aa3d81
hiram
  Wed Mar 18 19:09:58 2020 -0700
lastz runs for 12-way alignment on danRer10 per research request no redmine

diff --git src/hg/makeDb/doc/danRer10/lastzRuns.txt src/hg/makeDb/doc/danRer10/lastzRuns.txt
index 19863a2..484d18d 100644
--- src/hg/makeDb/doc/danRer10/lastzRuns.txt
+++ src/hg/makeDb/doc/danRer10/lastzRuns.txt
@@ -1,362 +1,584 @@
 #########################################################################
 # SWAP lastz zebrafish danRer10 (DONE - 2015-09-18 - Hiram)
     # the primary alignment on mm10
     cd /hive/data/genomes/mm10/bed/lastzDanRer10.2015-09-11
     cat fb.mm10.chainDanRer10Link.txt
     #	73464192 bases of 2652783500 (2.769%) in intersection
 
     #	and for the swap
     mkdir /hive/data/genomes/danRer10/bed/blastz.mm10.swap
     cd /hive/data/genomes/danRer10/bed/blastz.mm10.swap
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/mm10/bed/lastzDanRer10.2015-09-11/DEF \
         -workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
         -swap -chainMinScore=5000 -chainLinearGap=loose) > swap.log 2>&1 &
     #	real    16m8.387s
 
     cat  fb.danRer10.chainMm10Link.txt
     #	71611488 bases of 1369683683 (5.228%) in intersection
 
     time (doRecipBest.pl -buildDir=`pwd` danRer10 mm10) > rbest.log 2>&1
     #    real    7m34.259s
 
 #########################################################################
 # LASTZ Xenopus xenTro7 (DONE - 2017-02-09 - Hiram)
     mkdir /hive/data/genomes/danRer10/bed/lastzXenTro7.2017-02-09
     cd /hive/data/genomes/danRer10/bed/lastzXenTro7.2017-02-09
 
     printf '# zebrafish vs. X. tropicalis
 BLASTZ=/cluster/bin/penn/lastz-distrib-1.03.66/bin/lastz
 BLASTZ_M=254
 
 BLASTZ_H=2000
 BLASTZ_Y=3400
 BLASTZ_L=6000
 BLASTZ_K=2200
 BLASTZ_Q=/scratch/data/blastz/HoxD55.q
 
 # TARGET: Zebrafish danRer10
 SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
 SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
 SEQ1_CHUNK=20000000
 SEQ1_LAP=10000
 SEQ1_LIMIT=5
 
 # QUERY: X. tropicalis xenTro7
 SEQ2_DIR=/hive/data/genomes/xenTro7/xenTro7.2bit
 SEQ2_LEN=/hive/data/genomes/xenTro7/chrom.sizes
 SEQ2_CHUNK=10000000
 SEQ2_LAP=0
 SEQ2_LIMIT=40
 
 BASE=/hive/data/genomes/danRer10/bed/lastzXenTro7.2017-02-09
 TMPDIR=/dev/shm
 ' > DEF
 
     #	establish a screen to control this job
     screen
     time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
         -chainMinScore=5000 -chainLinearGap=loose \
           -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
             -bigClusterHub=ku) > do.log 2>&1
     #	lost tty connection
 
     time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
         -chainMinScore=5000 -chainLinearGap=loose \
           -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
             -continue=cat -bigClusterHub=ku) > cat.log 2>&1
     # real    136m6.704s
 
     cat fb.danRer10.chainXenTro7Link.txt
     #	90862965 bases of 1369683683 (6.634%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` danRer10 xenTro7) \
           > rbest.log 2>&1 &
     # real    387m16.949s
 
     # and for the swap:
     mkdir /hive/data/genomes/xenTro7/bed/blastz.danRer10.swap
     cd /hive/data/genomes/xenTro7/bed/blastz.danRer10.swap
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/danRer10/bed/lastzXenTro7.2017-02-09/DEF \
 	-chainMinScore=5000 -chainLinearGap=loose \
 	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
 	-syntenicNet -swap) > swap.log 2>&1
     #	real    30m3.142s
 
     cat fb.xenTro7.chainDanRer10Link.txt
     #	96433154 bases of 1365936747 (7.060%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` xenTro7 danRer10) \
           > rbest.log 2>&1
     # real    408m19.596s
 
 ########################################################################
 # LASTZ green spotted puffer tetNig2 (DONE - 2017-02-09 - Hiram)
     screen -S danRer10TetNig2
     mkdir /hive/data/genomes/danRer10/bed/lastzTetNig2.2017-02-09
     cd /hive/data/genomes/danRer10/bed/lastzTetNig2.2017-02-09
 
     printf '# zebrafish vs. green spotted puffer
 BLASTZ=/cluster/bin/penn/lastz-distrib-1.03.66/bin/lastz
 BLASTZ_M=254
 
 BLASTZ_H=2000
 BLASTZ_Y=9400
 BLASTZ_L=3000
 BLASTZ_K=3000
 BLASTZ_Q=/scratch/data/blastz/HoxD55.q
 
 # TARGET: Zebrafish danRer10
 SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
 SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
 SEQ1_CHUNK=20000000
 SEQ1_LAP=10000
 SEQ1_LIMIT=1
 
 # QUERY: green spotted puffer tetNig2
 SEQ2_DIR=/hive/data/genomes/tetNig2/tetNig2.2bit
 SEQ2_LEN=/hive/data/genomes/tetNig2/chrom.sizes
 SEQ2_CHUNK=10000000
 SEQ2_LAP=0
 SEQ2_LIMIT=1
 
 BASE=/hive/data/genomes/danRer10/bed/lastzTetNig2.2017-02-09
 TMPDIR=/dev/shm
 ' > DEF
 
     #	establish a screen to control this job
     screen
     time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
         -chainMinScore=2000 -chainLinearGap=medium \
           -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
             -bigClusterHub=ku) > do.log 2>&1
     #	real    97m22.745s
 
     cat fb.danRer10.chainTetNig2Link.txt
     #	83044644 bases of 1369683683 (6.063%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` danRer10 tetNig2) \
           > rbest.log 2>&1 &
     # real    254m45.837s
 
     mkdir /hive/data/genomes/tetNig2/bed/blastz.danRer10.swap
     cd /hive/data/genomes/tetNig2/bed/blastz.danRer10.swap
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/danRer10/bed/lastzTetNig2.2017-02-09/DEF \
 	-chainMinScore=2000 -chainLinearGap=medium \
 	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
 	-swap) > swap.log 2>&1
     #	real    6m59.881s
 
     cat fb.tetNig2.chainDanRer10Link.txt
     #	70573446 bases of 302314788 (23.344%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` tetNig2 danRer10) \
           > rbest.log 2>&1
     # real    228m19.188s
 
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/danRer10/bed/lastzTetNig2.2017-02-09/DEF \
 	-chainMinScore=2000 -chainLinearGap=medium \
 	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
 	-continue=syntenicNet -syntenicNet -swap) > synNet.log 2>&1
     # real    0m43.708s
 
 ########################################################################
 # LASTZ fugu fr3 (DONE - 2017-02-09 - Hiram)
     screen -S danRer10Fr3
     mkdir /hive/data/genomes/danRer10/bed/lastzFr3.2017-02-09
     cd /hive/data/genomes/danRer10/bed/lastzFr3.2017-02-09
 
     printf '# zebrafish vs. fugu
 BLASTZ=/cluster/bin/penn/lastz-distrib-1.03.66/bin/lastz
 BLASTZ_M=254
 
 BLASTZ_H=2000
 BLASTZ_Y=9400
 BLASTZ_L=3000
 BLASTZ_K=3000
 BLASTZ_Q=/scratch/data/blastz/HoxD55.q
 
 # TARGET: Zebrafish danRer10
 SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
 SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
 SEQ1_CHUNK=20000000
 SEQ1_LAP=10000
 SEQ1_LIMIT=6
 
 # QUERY: fugu fr3
 SEQ2_DIR=/hive/data/genomes/fr3/fr3.2bit
 SEQ2_LEN=/hive/data/genomes/fr3/chrom.sizes
 SEQ2_CHUNK=10000000
 SEQ2_LAP=0
 SEQ2_LIMIT=30
 
 BASE=/hive/data/genomes/danRer10/bed/lastzFr3.2017-02-09
 TMPDIR=/dev/shm
 ' > DEF
 
     #	establish a screen to control this job
     screen
     time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
         -chainMinScore=2000 -chainLinearGap=medium \
           -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
             -bigClusterHub=ku) > do.log 2>&1
     #	real    133m18.224s
 
     cat fb.danRer10.chainFr3Link.txt
     #	96978660 bases of 1369683683 (7.080%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` danRer10 fr3) \
           > rbest.log 2>&1 &
     # real    200m15.132s
 
     mkdir /hive/data/genomes/fr3/bed/blastz.danRer10.swap
     cd /hive/data/genomes/fr3/bed/blastz.danRer10.swap
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/danRer10/bed/lastzFr3.2017-02-09/DEF \
 	-chainMinScore=2000 -chainLinearGap=medium \
 	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
 	-syntenicNet -swap) > swap.log 2>&1
     #	real    9m31.601s
 
     cat fb.fr3.chainDanRer10Link.txt
     #	79663999 bases of 350961831 (22.699%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` fr3 danRer10) \
           > rbest.log 2>&1
     # real    181m55.550s
 
 ########################################################################
 # LASTZ medaka oryLat2 (DONE - 2017-02-09 - Hiram)
     screen -S oryLat2DanRer10
     mkdir /hive/data/genomes/danRer10/bed/lastzOryLat2.2017-02-09
     cd /hive/data/genomes/danRer10/bed/lastzOryLat2.2017-02-09
 
     printf '# zebrafish vs. medaka
 BLASTZ=/cluster/bin/penn/lastz-distrib-1.03.66/bin/lastz
 BLASTZ_M=254
 
 BLASTZ_H=2000
 BLASTZ_Y=9400
 BLASTZ_L=3000
 BLASTZ_K=3000
 BLASTZ_Q=/scratch/data/blastz/HoxD55.q
 
 # TARGET: Zebrafish danRer10
 SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
 SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
 SEQ1_CHUNK=20000000
 SEQ1_LAP=10000
 SEQ1_LIMIT=6
 
 # QUERY: medaka oryLat2
 SEQ2_DIR=/hive/data/genomes/oryLat2/oryLat2.2bit
 SEQ2_LEN=/hive/data/genomes/oryLat2/chrom.sizes
 SEQ2_CHUNK=10000000
 SEQ2_LAP=0
 SEQ2_LIMIT=30
 
 BASE=/hive/data/genomes/danRer10/bed/lastzOryLat2.2017-02-09
 TMPDIR=/dev/shm
 ' > DEF
 
     #	establish a screen to control this job
     screen
     time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
         -chainMinScore=2000 -chainLinearGap=medium \
           -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
             -bigClusterHub=ku) > do.log 2>&1
     #	real    202m52.634s
 
     cat fb.danRer10.chainOryLat2Link.txt
     #	132042172 bases of 1369683683 (9.640%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` danRer10 oryLat2) \
           > rbest.log 2>&1 &
     # real    388m46.359s
 
     mkdir /hive/data/genomes/oryLat2/bed/blastz.danRer10.swap
     cd /hive/data/genomes/oryLat2/bed/blastz.danRer10.swap
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/danRer10/bed/lastzOryLat2.2017-02-09/DEF \
 	-chainMinScore=2000 -chainLinearGap=medium \
 	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
 	-syntenicNet -swap) > swap.log 2>&1
     #	real    18m21.238s
 
     cat fb.oryLat2.chainDanRer10Link.txt
     #	123853592 bases of 700386597 (17.684%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` oryLat2 danRer10) \
           > rbest.log 2>&1
     # real    370m26.030s
 
 ########################################################################
 # LASTZ stickleback gasAcu1 (DONE - 2017-02-09 - Hiram)
     screen -S gasAcu1DanRer10
     mkdir /hive/data/genomes/danRer10/bed/lastzGasAcu1.2017-02-09
     cd /hive/data/genomes/danRer10/bed/lastzGasAcu1.2017-02-09
 
     printf '# zebrafish vs. stickleback
 BLASTZ=/cluster/bin/penn/lastz-distrib-1.03.66/bin/lastz
 BLASTZ_M=254
 
 BLASTZ_H=2000
 BLASTZ_Y=9400
 BLASTZ_L=3000
 BLASTZ_K=3000
 BLASTZ_Q=/scratch/data/blastz/HoxD55.q
 
 # TARGET: Zebrafish danRer10
 SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
 SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
 SEQ1_CHUNK=20000000
 SEQ1_LAP=10000
 SEQ1_LIMIT=6
 
 # QUERY: stickleback gasAcu1
 #  30,000,000 is enough to work with the biggest chrom as one item
 SEQ2_DIR=/hive/data/genomes/gasAcu1/gasAcu1.2bit
 SEQ2_LEN=/hive/data/genomes/gasAcu1/chrom.sizes
 SEQ2_CHUNK=30000000
 SEQ2_LAP=0
 SEQ2_LIMIT=30
 
 BASE=/hive/data/genomes/danRer10/bed/lastzGasAcu1.2017-02-09
 TMPDIR=/dev/shm
 ' > DEF
 
     #	establish a screen to control this job
     screen
     time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
         -chainMinScore=2000 -chainLinearGap=medium \
           -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
             -bigClusterHub=ku) > do.log 2>&1
     #	real    766m31.436s
 
     cat fb.danRer10.chainGasAcu1Link.txt
     #	134422269 bases of 1369683683 (9.814%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` danRer10 gasAcu1) \
           > rbest.log 2>&1 &
     # real    466m55.498s
 
     mkdir /hive/data/genomes/gasAcu1/bed/blastz.danRer10.swap
     cd /hive/data/genomes/gasAcu1/bed/blastz.danRer10.swap
     time (doBlastzChainNet.pl -verbose=2 \
 	/hive/data/genomes/danRer10/bed/lastzGasAcu1.2017-02-09/DEF \
 	-chainMinScore=2000 -chainLinearGap=medium \
 	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
 	-syntenicNet -swap) > swap.log 2>&1
     #	real    26m37.898s
 
     cat fb.gasAcu1.chainDanRer10Link.txt
     #	123076224 bases of 446627861 (27.557%) in intersection
 
     time (doRecipBest.pl -workhorse=hgwdev -buildDir=`pwd` gasAcu1 danRer10) \
           > rbest.log 2>&1
     # real    441m12.898s
 
 ########################################################################
+# LASTZ Coelacanth latCha1 (DONE - 2020-02-25 - Hiram)
+    mkdir /hive/data/genomes/danRer10/bed/lastzLatCha1.2020-02-25
+    cd /hive/data/genomes/danRer10/bed/lastzLatCha1.2020-02-25
+
+    printf '# zebrafish vs. Coelacanth
+BLASTZ=/cluster/bin/penn/lastz-distrib-1.04.00/bin/lastz
+BLASTZ_M=254
+
+BLASTZ_H=2000
+BLASTZ_Y=9400
+BLASTZ_L=3000
+BLASTZ_K=3000
+BLASTZ_Q=/cluster/data/blastz/HoxD55.q
+
+# TARGET: Zebrafish danRer10
+SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
+SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
+SEQ1_CHUNK=20000000
+SEQ1_LAP=10000
+SEQ1_LIMIT=6
+
+# QUERY: Coelacanth latCha1
+#  14,000,000 is enough to work with the biggest chrom as one item
+SEQ2_DIR=/hive/data/genomes/latCha1/latCha1.2bit
+SEQ2_LEN=/hive/data/genomes/latCha1/chrom.sizes
+SEQ2_CHUNK=14000000
+SEQ2_LAP=0
+SEQ2_LIMIT=30
+
+BASE=/hive/data/genomes/danRer10/bed/lastzLatCha1.2020-02-25
+TMPDIR=/dev/shm
+' > DEF
+
+    #	establish a screen to control this job
+    screen
+    time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
+        -chainMinScore=5000 -chainLinearGap=loose \
+          -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
+            -bigClusterHub=ku) > do.log 2>&1
+    #	real    177m11.851s
+
+    cat fb.danRer10.chainLatCha1Link.txt
+    #	86552427 bases of 1369683683 (6.319%) in intersection
+    cat fb.danRer10.chainSynLatCha1Link.txt
+    #	15892801 bases of 1369683683 (1.160%) in intersection
+
+    time (doRecipBest.pl -load -workhorse=hgwdev -buildDir=`pwd` \
+          danRer10 latCha1) > rbest.log 2>&1 &
+    # real    71m59.526s
+
+    cat fb.danRer10.chainRBest.LatCha1.txt
+    #    56607816 bases of 1369683683 (4.133%) in intersection
+
+    mkdir /hive/data/genomes/latCha1/bed/blastz.danRer10.swap
+    cd /hive/data/genomes/latCha1/bed/blastz.danRer10.swap
+    time (doBlastzChainNet.pl -verbose=2 \
+	/hive/data/genomes/danRer10/bed/lastzLatCha1.2020-02-25/DEF \
+	-chainMinScore=5000 -chainLinearGap=loose \
+	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
+	-syntenicNet -swap) > swap.log 2>&1
+    #	real    12m58.361s
+
+    cat fb.latCha1.chainDanRer10Link.txt
+    #	98338936 bases of 2183592768 (4.504%) in intersection
+    cat fb.latCha1.chainSynDanRer10Link.txt
+    #   13550035 bases of 2183592768 (0.621%) in intersection
+
+    time (doRecipBest.pl -load -workhorse=hgwdev -buildDir=`pwd` \
+          latCha1 danRer10) > rbest.log 2>&1
+    # real    67m29.683s
+    cat fb.latCha1.chainRBest.DanRer10.txt
+    # 56742837 bases of 2183592768 (2.599%) in intersection
+
+########################################################################
+# LASTZ spotted gar lepOcu1 (DONE - 2020-02-25 - Hiram)
+    mkdir /hive/data/genomes/danRer10/bed/lastzLepOcu1.2020-02-25
+    cd /hive/data/genomes/danRer10/bed/lastzLepOcu1.2020-02-25
+
+    printf '# zebrafish vs. spotted gar
+BLASTZ=/cluster/bin/penn/lastz-distrib-1.04.00/bin/lastz
+BLASTZ_M=254
+
+BLASTZ_H=2000
+BLASTZ_Y=9400
+BLASTZ_L=3000
+BLASTZ_K=3000
+BLASTZ_Q=/cluster/data/blastz/HoxD55.q
+
+# TARGET: Zebrafish danRer10
+SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
+SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
+SEQ1_CHUNK=20000000
+SEQ1_LAP=10000
+SEQ1_LIMIT=6
+
+# QUERY: spotted gar lepOcu1
+SEQ2_DIR=/hive/data/genomes/lepOcu1/lepOcu1.2bit
+SEQ2_LEN=/hive/data/genomes/lepOcu1/chrom.sizes
+SEQ2_CHUNK=20000000
+SEQ2_LAP=0
+SEQ2_LIMIT=30
+
+BASE=/hive/data/genomes/danRer10/bed/lastzLepOcu1.2020-02-25
+TMPDIR=/dev/shm
+' > DEF
+
+    #	establish a screen to control this job
+    screen
+    time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
+        -chainMinScore=5000 -chainLinearGap=loose \
+          -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
+            -bigClusterHub=ku) > do.log 2>&1
+    #	real    118m59.600s
+
+    cat fb.danRer10.chainLepOcu1Link.txt
+    #	115180491 bases of 1369683683 (8.409%) in intersection
+    cat fb.danRer10.chainSynLepOcu1Link.txt
+    #    58800217 bases of 1369683683 (4.293%) in intersection
+
+    time (doRecipBest.pl -load -workhorse=hgwdev -buildDir=`pwd` danRer10 \
+	lepOcu1) > rbest.log 2>&1 &
+    # real    88m25.172s
+
+    cat fb.danRer10.chainRBest.LepOcu1.txt
+    #	78985057 bases of 1369683683 (5.767%) in intersection
+
+    mkdir /hive/data/genomes/lepOcu1/bed/blastz.danRer10.swap
+    cd /hive/data/genomes/lepOcu1/bed/blastz.danRer10.swap
+    time (doBlastzChainNet.pl -verbose=2 \
+	/hive/data/genomes/danRer10/bed/lastzLepOcu1.2020-02-25/DEF \
+	-chainMinScore=5000 -chainLinearGap=loose \
+	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
+	-syntenicNet -swap) > swap.log 2>&1
+    #	real    7m34.876s
+
+    cat fb.lepOcu1.chainDanRer10Link.txt
+    #	98189747 bases of 869414361 (11.294%) in intersection
+    cat fb.lepOcu1.chainSynDanRer10Link.txt
+    #   47688590 bases of 869414361 (5.485%) in intersection
+
+    time (doRecipBest.pl -load -workhorse=hgwdev -buildDir=`pwd` \
+          lepOcu1 danRer10) > rbest.log 2>&1
+    # real    83m11.208s
+
+    cat fb.lepOcu1.chainRBest.DanRer10.txt
+    #	78000762 bases of 869414361 (8.972%) in intersection
+
+########################################################################
+# LASTZ Elephant shark calMil1 (DONE - 2020-02-25 - Hiram)
+    mkdir /hive/data/genomes/danRer10/bed/lastzCalMil1.2020-02-25
+    cd /hive/data/genomes/danRer10/bed/lastzCalMil1.2020-02-25
+
+    printf '# zebrafish vs. Elephant shark
+BLASTZ=/cluster/bin/penn/lastz-distrib-1.04.00/bin/lastz
+BLASTZ_M=254
+
+BLASTZ_H=2000
+BLASTZ_Y=9400
+BLASTZ_L=3000
+BLASTZ_K=3000
+BLASTZ_Q=/cluster/data/blastz/HoxD55.q
+
+# TARGET: Zebrafish danRer10
+SEQ1_DIR=/hive/data/genomes/danRer10/danRer10.2bit
+SEQ1_LEN=/hive/data/genomes/danRer10/chrom.sizes
+SEQ1_CHUNK=20000000
+SEQ1_LAP=10000
+SEQ1_LIMIT=6
+
+# QUERY: Elephant shark calMil1
+SEQ2_DIR=/hive/data/genomes/calMil1/calMil1.2bit
+SEQ2_LEN=/hive/data/genomes/calMil1/chrom.sizes
+SEQ2_CHUNK=20000000
+SEQ2_LAP=0
+SEQ2_LIMIT=100
+
+BASE=/hive/data/genomes/danRer10/bed/lastzCalMil1.2020-02-25
+TMPDIR=/dev/shm
+' > DEF
+
+    #	establish a screen to control this job
+    screen
+    time (doBlastzChainNet.pl -verbose=2 `pwd`/DEF \
+        -chainMinScore=5000 -chainLinearGap=loose \
+          -syntenicNet -workhorse=hgwdev -smallClusterHub=ku \
+            -bigClusterHub=ku) > do.log 2>&1
+    #	real    48m39.821s
+
+    cat fb.danRer10.chainCalMil1Link.txt
+    #	76690714 bases of 1369683683 (5.599%) in intersection
+    cat fb.danRer10.chainSynCalMil1Link.txt
+    #   18240388 bases of 1369683683 (1.332%) in intersection
+
+    time (doRecipBest.pl -load -workhorse=hgwdev -buildDir=`pwd` danRer10 \
+	calMil1) > rbest.log 2>&1 &
+    # real    466m55.498s
+
+    cat fb.danRer10.chainRBest.CalMil1.txt
+    # 48435763 bases of 1369683683 (3.536%) in intersection
+
+    mkdir /hive/data/genomes/calMil1/bed/blastz.danRer10.swap
+    cd /hive/data/genomes/calMil1/bed/blastz.danRer10.swap
+    time (doBlastzChainNet.pl -verbose=2 \
+	/hive/data/genomes/danRer10/bed/lastzCalMil1.2020-02-25/DEF \
+	-chainMinScore=5000 -chainLinearGap=loose \
+	-workhorse=hgwdev -smallClusterHub=ku -bigClusterHub=ku \
+	-syntenicNet -swap) > swap.log 2>&1
+    #	real    7m34.876s
+
+    cat fb.calMil1.chainDanRer10Link.txt
+    #	66411165 bases of 936953458 (7.088%) in intersection
+    cat fb.calMil1.chainSynDanRer10Link.txt
+    #   15359860 bases of 936953458 (1.639%) in intersection
+
+    time (doRecipBest.pl -load -workhorse=hgwdev -buildDir=`pwd` \
+          calMil1 danRer10) > rbest.log 2>&1
+    # real    57m38.923s
+
+    cat fb.calMil1.chainRBest.DanRer10.txt
+    #   47381650 bases of 936953458 (5.057%) in intersection
+
+########################################################################