03b614da15d6d8f07f0b974735e84d8fc42bf39c bnguy Fri Apr 3 14:25:45 2020 -0700 Update on projects and tools page regarding NS forest and pyle diff --git src/hg/cirm/gateway/htdocs/projects.html src/hg/cirm/gateway/htdocs/projects.html index 22d0cc5..0669822 100755 --- src/hg/cirm/gateway/htdocs/projects.html +++ src/hg/cirm/gateway/htdocs/projects.html @@ -1,1615 +1,1623 @@ <!DOCTYPE html> <!--#set var="TITLE" value="CIRM Stem Cell Hub Projects" --> <!--#include virtual="setRoot.html" --> <!--#include virtual="${ROOT}inc/header.html" --> <div class="cirm-page-body"> <div class="cirm-page-title back-light-blue" style="//background: #1E90FF;"> <h5 class="cirm-page-title-text">Projects initiated and funded by the CESCG</h5> </div> <br> <!--<div class="table-responsive scrollable-table" style="/*padding-right: 80px;*/">--> <div style="padding-right: 80px"> <table class="table table-hover table-header-rotated" style="overflow: visible"> <thead> <tr> <!-- <th style="width: 1%;" class="text-nowrap"> Research Theme </th> <th style="width: 1%;" class="text-nowrap"> Lab </th> <th style="width: 1%;" class="text-nowrap "> Data Set </th> --> <th colspan=3 rowspan=2 class="text-nowrap "></th> <th style="width: 1%;" class="text-dark-blue text-nowrap"> Single cell <a href="https://en.wikipedia.org/wiki/Single-cell_analysis" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="It is possible to assay individual cells from a population to learn more about the cells making up a community, also known as studying the <em>cellular heterogenetity</em>." data-content="Click the info icon to read more on Wikipedia."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> </th> <th style="width: 1%;" class="rotate-45 text-dark-pink"> <div> <span> <a href="https://en.wikipedia.org/wiki/Whole_genome_sequencing" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Whole genome sequencing." data-content="Click the info icon to read more on Wikipedia."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> WGS </span> </div> </th> <th style="width: 1%;" class="text-nowrap rotate-45 text-dark-pink"> <div> <span> <a href="https://www.illumina.com/techniques/sequencing/dna-sequencing/targeted-resequencing/amplicon-sequencing.html" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="A method for sequencing a specific region of interest. Similar to AMP-seq." data-content="Click the info icon to read more on the Illumina website."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> Amplicon-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-blue"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/19015660" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Some RNA-seq is done on bulk tissue, though for this project much of it is done on single cells. The icons in the single cell column indicate how the cells were handled to generate the RNA-seq data." data-content="Click info icon to read a review paper of RNA-seq (2009)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> RNA-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-blue"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/22081020" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Genotyping method. Based on capturing and sequencing specifc regions of the genome." data-content="Click info icon to read the Capture-seq paper (2011)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> Capture-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-blue"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/23783272" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="A method to distinguish RNA from different subcellular fractionations." data-content="Click info icon to read the Frac-seq paper (2013)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> Frac-seq </span> </div> </th> <th style="width: 1%;" class="text-nowrap rotate-45 text-light-green"> <div> <span> <a href="https://en.wikipedia.org/wiki/ChIP-sequencing" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Used to profile histone modifications." data-content="Click the info icon to read more on Wikipedia."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> broad-ChIP-seq </span> </div> </th> <th style="width: 1%;" class="text-nowrap rotate-45 text-light-green"> <div> <span> <a href="https://en.wikipedia.org/wiki/ChIP-sequencing" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Used to profile transcription factor (TF) binding sites." data-content="Click the info icon to read more on Wikipedia."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> narrow-ChIP-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-green"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/28973448" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Targeted chromatin ligation sequencing. Used in epigenetics to capture histone modification patterns low-cell count experiments." data-content="Click the info icon to read the TCL-seq paper (2017)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> TCL-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-green"> <div> <span> <a href="https://en.wikipedia.org/wiki/Whole_genome_bisulfite_sequencing" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Whole genome bisulfite sequencing. A method for looking at methylation throughout the genome." data-content="Click the info icon to read more on Wikipedia."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> WGBS </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-green"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/16224102" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Reduced-representation Bisulifite Sequencing to determine methylation of promoter sites" data-content="Click the info icon to read the RRBS paper (2005)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> RRBS </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-green"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/25559105" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Transposase-Accessible Chromatin with high throughput sequencing" data-content="Click the info icon to read the ATAC-seq paper (2015)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> ATAC-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-light-green"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/20461051" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Assay to determine spatial organization of chromatin" data-content="Click the info icon to read the Hi-C paper (2010)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> Hi-C </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-orange"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/25513782" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Genome-wide Unbiased Identifications of double strand breaks (DSBs) Evaluated by Sequencing." data-content="Click the info icon to read the GUIDE-seq paper (2014)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> GUIDE-seq </span> </div> </th> <th style="width: 1%;" class="rotate-45 text-dark-blue"> <div> <span> <a href="https://www.ncbi.nlm.nih.gov/pubmed/27365449" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="In this project, imaging is only used in the context of spatial transcriptomics where flourescent probes are used to measure both the relative expression of specific genes and where these genes are being activated." data-content="Click info icon to read the Spatial Transcriptomics paper (2016)."> <i class="fas fa-info-circle" aria-hidden="true"></i></a> Imaging </span> </div> </th> </tr> </thead> <tbody> <tr style="font-size: 75%"> <td colspan="3"></td> <td class="text-dark-blue text-nowrap"></td> <td colspan="2" class="text-dark-pink"></td> <td colspan="3" class="text-light-blue"></td> <td colspan="3" class="text-light-green text-center"> Histone modification </td> <td colspan="2" class="text-light-green text-center"> Methylome </td> <td colspan="2" class="text-light-green text-nowrap text-center"> Chromatin<br>modeling </td> <td colspan="1" class="text-orange text-nowrap text-center"> Gene editing<br>profiling </td> <td colspan="1" class="text-dark-blue"></td> </tr> <tr> <!-- <td colspan="3"></td> --> <td class="text-nowrap"> <b>Research Theme</b> </td> <td> <b>Lab</b> </td> <td> <b>Dataset</b> </td> <td class="text-dark-blue text-nowrap"></td> <td colspan="2" class="text-dark-pink text-center">Genomics</td> <td colspan="3" class="text-light-blue text-center">Transcriptomics</td> <td colspan="7" class="text-light-green text-center">Epigenomics</td> <td colspan="1" class="text-orange"></td> <td colspan="1" class="text-dark-blue"></td> </tr> <!-- EXAMPLE LAB AND DATASET ROW <tr> <td></td> <td class="lab text-nowrap"> Smith </td> <td class="datasetid"> labAssaySample </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-orange text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> </tr> --> <tr class="table-active"> <td colspan="100%">Blood stem cells</td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://baldwin.scripps.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Kristin Baldwin, Scripps" data-content="The Baldwin lab is studying a matched set of iPSC lines from patients with cardiovascular disease.">Baldwin</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid text-nowrap"> baldwin12PairedIpscCellLines1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="A study of the mutagenic effects of the induction process by comparing two different methods of induction using fribroblast-derived iPSC lines."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="https://cornlab.com/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Jacob Corn, UC Berkeley" data-content="The Corn lab is investigating fixing sickle cell anemia with CRISPR. Aim 1 of the Corn lab is to use RNA-seq to explore erythroid (red blood cell) maturation. Aim 2 is using boutique DNA-seq methods to investigate effets of using CRISPR.">Corn</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/cornErythroidMaturation">cornErythroidMaturation</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Investigating erythoid maturation with RNA-seq."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/cornOffTarget">cornOffTarget</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Investigating CRISPR off-target cleavage sites using GUIDE-seq, Amplicon-seq and Capture-seq."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> cornHspc <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Single cell RNA-seq of hematopoietic stem cells using 10X to identify hematopoietic stem and progenitor cells."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://www.crooks-lab.com/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Gay Crooks, UCLA" data-content="The Crooks Lab is working to create a comprehensive transcriptome and epigenome map of human hematopoetic stem cell (HSC) ontogeny by comparing human hematopoietic tissues and cells derived from embryonic stem cells (ESCs).">Crooks</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> crooksHsc <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="RNA-seq data from fetal liver."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://stemcellphd.stanford.edu/faculty/irv-weissman.html" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Irv Weissman, Stanford" data-content="The Weissman lab is working on identifying and characterizing the progression of discrete changes, genetic and epigenetic, that leads to the generation of cancer stem cells (CSCs) from a variety of blood and solid tissue cancers.">Weissman</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> weissmanHsc1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Single-cell RNA-seq of the rare, blood-forming haematopoietic stem cells (HSCs) in bone marrow. Bone marrow cells were separated using FACS with sorting on standard, in-house developed markers."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr class="table-active"> <td colspan="100%">Cardiac biology</td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://bruneaulab.gladstone.org/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Benoit Bruneau, UCSF" data-content="The Bruneau lab is investigating transcriptomic and epigenetic analysis of iPSC-derived cardiomyocytes at four stages of differentiation.">Bruneau</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> bruneauCardioEpigenetics1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="A study to discern basic gene regulating mechanisms of iPSC derived cardiomyocytes at four stages of differentiation."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> bruneauTbx5 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Using two different cardiac differentiation protocols, human gene expression programs are defined that are susceptible to TBX5 dosage at single cell resolution in iPSC-derived cardiomyocytes."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://cardiology.ucsd.edu/research/labs/chi-lab/Pages/default.aspx" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Neil Chi, UCSD" data-content="The Chi lab is generating human cardiac stem cells and functional cardiomyocytes for cardiac and vascular regenerative repairs.">Chi</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> chiCardiomyocyte1 <i class="fas fa-info-circle" aria-hidden="true" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Analysis of in vitro and in vivo human cardiovascular lineages" data-content="Discovery of gene regulatory networks that facilitate the differentiation of human pluripotent stem cells (hPSC) into ventricular and atrial cardiomyocyte (CM) lineages using single cell RNA-seq (scRNA-Seq) on cells derived from human hearts at different developmental stages."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fa fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> chiMouseCardiomyocyte <i class="fas fa-info-circle" aria-hidden="true" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="" data-content="To discover transcriptional networks that regulate the differentiation of mouse cardiovascular lineages."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://frazer.ucsd.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Kelly Frazer, UCSD" data-content="The Frazer lab is focused on performing high-throughput phenotypic characterization of iPSC-derived cardiomyocytes from a diverse set of ethnicities to enable further genetic studies investigating the segregation of traits.">Frazer</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i></td> <td class="datasetid"> frazerCardIps1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Generation of human iPSC and iPSC-derived cardiomyocytes from 222 individuals."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://www.salk.edu/scientist/katherine-jones/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Kathy Jones, The Salk Institute" data-content="The Jones lab is investigating the role of transcriptional regulators Yap1 and P-TEFb in human embryonic stem cell differentiation towards cardiomyocytes.">Jones</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> jonesYap1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Studying the role of Yap1 and P-TEFb in hESC Differentiation towards cardiomyocytes."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://snyderlab.stanford.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Mike Snyder, Stanford" data-content="The Snyder lab is investigating drug response of hypertrophic cardiomyopathy (HCM), dialated cardiomyopathy (DCM), and healthy (control) donors with a comprehensive survey combining iPSC-cardiac differentiation, drug treatment and genomic and transcriptomic analysis.">Snyder</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> / <a href="http://med.stanford.edu/wulab.html" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Joseph Wu, Stanford" data-content="The Wu lab is investigating patient-specific and disease-specific induced pluripotent stem cells (iPSCs) and their uses in drug discovery and clinical trials.">Wu</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/snyderCardIps1">snyderCardIps1</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="A comprehensive survey combining iPSC-cardiac differentiation, drug treatment, genomic, and transcriptomic analysis applied to these iPSC lines to assess the drug response of each individual patient."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr class="table-active"> <td colspan="100%">Molecular regulators of stem cells</td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://belmonte.salk.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Juan Carlos Izpisua-Belmonte, The Salk Insitute" data-content="The Belmonte lab is working to characterize the molecular dynamics of cells undergoing 4F-induced reprogramming in vivo in the mouse.">Belmonte</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> belmonteMouseDnmt3a <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Short-term reprogramming of mouse spleens in-vivo by low 4F induction using Doxycycline treatment, in DNMT3a deficient mice."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="https://fan.genetics.ucla.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Guoping Fan, UCLA" data-content="The Fan lab is working on identifying convergent target genes and signaling pathways perturbed in human overgrowth syndrome.">Fan</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/fanIcf1">fanIcf1</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="WGBS, RRBS, WGS, ChIP-seq, and RNA-seq on iPSCs generated from patients with human overgrowth syndrome."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="https://sanfordlab.mcdb.ucsc.edu/Sanford_Lab/Welcome.html" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Jeremy Sanford, UCSC" data-content="The Sanford lab is studying how alternative pre-mRNA splicing contributes to the regulation of gene expression and protein diversity.">Sanford</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> sanfordRnaRegulation1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="CLIP-seq and RNA-seq on human stem cells and human neural progenitor cells."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://aprilpylelab.com/" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="April Pyle, UCLA" - data-content="The Sanford lab is studying Human Developmental Somitogenesis and Myogenesis.">Pyle</a> + data-content="The Pyle lab is studying Human Developmental Somitogenesis and Myogenesis.">Pyle</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> pyleSkeletalMuscle + <i class="fas fa-info-circle popoveradjust" aria-hidden="true" + data-toggle="popover" data-trigger="hover" + data-placement="top" data-container="body" data-html="true" + title="" + data-content=" + RNA-seq on embryonic, fetal, and postnatal cells."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> - <td class="text-light-blue text-center"></td> + <td class="text-light-blue text-center"> + <i class="fas fa-square" aria-hidden="true"></i> + </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr class="table-active"> <td colspan="100%">Neurobiology</td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://baldwin.scripps.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Kristin Baldwin, Scripps" data-content="The Baldwin lab is studying a matched set of iPSC lines from patients with cardiovascular disease.">Baldwin</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid text-nowrap"> baldwinMouseNeurons <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content=""></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="https://www.uclahealth.org/daniel-geschwind" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Daniel Geschwind, UCLA" data-content="The Geschwind lab is exploring how multiple distinct mutations lead to the convergent pathology of autism spectrum disorder. They are analyzing the iPSC organoids from the Pasca lab.">Geschwind</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> / <a href="http://www.pascalab.org/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Sergiu Pasca, Stanford" data-content="The Pasca lab is growing brain organoids with neurological disorders including deletions, duplications and triplications of 16p11.2, Timothy syndrome, epilepsy and mental retardation limited to female (EFMR).">Pasca</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> geschwindNeurospheres1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Using iPSC-based models and neurosphere RNA-seq data to study autism spectrum disorder."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="https://kriegsteinlab.ucsf.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Arnold Kriegstein, UCSF" data-content="The Kriegstein lab is using single-cell RNA profiling to learn about the diverse population of cortical neurons.">Kriegstein</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/kriegsteinBrainOrganoids1">kriegsteinBrainOrganoids1</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="Single-cell Brain Organoids" data-content="874 iPSC-derived brain organoid samples processed via single-cell RNA-seq."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/kriegsteinBrainOrganoids2">kriegsteinBrainOrganoids2</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="Single-cell Brain Organoids" data-content="Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution"></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/kriegsteinRadialGliaStudy1" >kriegsteinRadialGliaStudy1</a> <i class="fas fa-info-circle" aria-hidden="true" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Single-cell Study of Brain Development" data-content="376 primary samples of fetal radial glial cells that were processed via single-cell RNA-seq."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/kriegstein6k">kriegstein6k</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="RNA-seq from 6,000 primary cells at UCSF."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <!-- <tr> <td></td> <td class="lab text-nowrap"> <a href="https://med.stanford.edu/stemcell/about/Laboratories/clarke.html" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Michael F. Clarke, Stanford" data-content="The Clarke lab is collaborating with the Quake lab in exploring chromatin landscapes.">Clarke</a> </td> <td class="datasetid"></td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> </tr> --> <tr> <td></td> <!-- <a href="#" title="Dismissible popover" data-toggle="popover" data-trigger="focus" data-content="C">Click me</a> --> <td class="lab text-nowrap"> <a href="https://quakelab.stanford.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Stephen Quake, Stanford University" data-content="The Quake lab is working on characterizing cell subpopulations of healthy and pathological tissues of the brain and pancreas. He is also looking at gene and epigenetic properties of organ lineages to compare stem cell differentiation hierarchy to normal tissues to elucidate mechanisms of pathogenesis.">Quake</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/quakeBrainGeo1">quakeBrainGeo1</a> <i class="fas fa-info-circle" aria-hidden="true" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="" data-content="Examination of cell types in healthy human brain samples."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square text-light-blue" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/quakeGlioblastomaGeo1">quakeGlioblastomaGeo1</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Characterizing the effects of glioblastoma on normal brain."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-s text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="http://yeolab.github.io/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Gene Yeo, UCSD" data-content="The Yeo lab is exploring how RNA localizes in certain parts of the cell, effecting differentiation, stress and neurodegeneration, particularly with regards to ALS (amytrophic lateral sclerosis).">Yeo</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> yeoAlsRna <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="Yeo Lab ALS RNA pateint RNA-seq" data-content="RNA sequence from cells derived from ALS patients and controls. The RNA is separated into various compartments including cytoplasmic and total cellular."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> yeoCorticalOrganoid <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="Yeo Lab single cell RNA-seq of cortical organoids" data-content="Single cell 10x platform RNA-seq data from cortical organoids derived from patients with Myotonic Dystrophy and controls."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> yeoRnaLocalization1 <i class="fas fa-info-circle popoveradjust" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="Investigating ALS with Frac-seq" data-content="Global subcellular mRNA localization in differentiation, stress, and neurodegeneration."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr class="table-active"> <td colspan="100%">Pancreas</td> </tr> <tr> <td></td> <td class="lab text-nowrap"> <a href="https://quakelab.stanford.edu/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Stephen Quake, Stanford University" data-content="The Quake lab is working on characterizing cell subpopulations of healthy and pathological tissues of the brain and pancreas. They are also looking at gene and epigenetic properties of organ lineages to compare stem cell differentiation hierarchy to normal tissues to elucidate mechanisms of pathogenesis.">Quake</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/quakeAdultAgingPancreas1">quakeAdultAgingPancreas1</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Single cell transcriptome analysis of human pancreas reveals transcriptional signatures of aging and somatic mutation patterns."></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <!-- <td class="datasetid"> FYI the following SSI command comment was disabled to avoid nesting comments. replace ~~ with dash dash to restore it <a href="<!~~ #echo var='ROOT'~~>d/quakeFetalPancreasSpatial">quakeFetalPancreasSpatial</a>--> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/quakeFetalPancreasSpatial">quakeFetalPancreasSpatial</a> <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Analysis of the spatial distribution of single mRNA molecules measured by in situ sequencing on human fetal pancreas at three developmental time points–80, 87 and 117 days post-fertilization"></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> </tr> <tr> <td></td> <td class="lab text-nowrap"></td> <td class="datasetid"> <a href="<!--#echo var='ROOT'-->d/quakeTumorProfiling1">quakeTumorProfiling1</a> <i class="fas fa-info-circle popoveradjust" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="Quake lab tumours RNA-seq" data-content="Profiling tumor cells with single cell RNA-seq"></i> </td> <td class="text-dark-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> </tr> <tr class="table-active"> <td colspan="100%">Therapeutics</td> </tr> <tr class="last-row"> <td></td> <td class="lab text-nowrap"> <a href="http://www.scripps.edu/loring/" target="_blank" data-toggle="popover" data-trigger="hover" class="popoveradjust" data-placement="top" data-container="body" data-html="true" title="Jeanne Loring, Scripps" data-content="The Loring lab is carrying out preclinical studies to develop an autologous cell therapy for Parkinson's disease.">Loring</a> <i class="fas fa-external-link-alt icon-sm" aria-hidden="true"></i> </td> <td class="datasetid"> loringParkinsons1 <i class="fas fa-info-circle popoveradjust" aria-hidden="true" data-toggle="popover" data-trigger="hover" data-placement="top" data-container="body" data-html="true" title="" data-content="Genomics-based assays to determine if cells remain genomically-intact during differentiation for transplantation."></i> </td> <td class="text-dark-blue text-center"></td> <td class="text-dark-pink text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-dark-pink text-center"></td> <td class="text-light-blue text-center"> <i class="fas fa-square" aria-hidden="true"></i> </td> <td class="text-light-blue text-center"></td> <td class="text-light-blue text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-light-green text-center"></td> <td class="text-orange text-center"></td> <td class="text-dark-blue text-center"></td> 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