The SARS-CoV-2 coronavirus emerged in December 2019 as a novel human pathogen causing a severe acute respiratory syndrome (COVID-19). In the following months, the disease spread internationally and was declared a pandemic by the World Health Organization on March 11, 2020.
- ++Genome sequencing of the SARS-CoV-2 coronavirus has helped researchers study mechanisms of +transmission and infection and the reaction of the human immune system. Compared to other RNA viruses, the genome mutates little, but enough variants are known to determine how samples cluster into +groups and how they are related (as illustrated by the accompanying COVID-19 transmission map). +COVID-19 related datasets in the human genome are also beginning to become publicly available in +sufficient volume to merit meta-analysis and summarization, and can shed light on, for example, +genetic influences on infection susceptibility, disease severity, and outcomes. +
We at the UC Santa Cruz Genomics Institute are responding to the urgency of supporting biomedical research aimed at -developing therapeutics and a vaccine for this devastating illness by fast-tracking the -UCSC Genome Browser for SARS-Cov-2 -and incorporating relevant biomedical datasets such as single-cell lung gene expression into the -UCSC Cell Browser. +developing therapeutics and a vaccine for this devastating illness by fast-tracking our +visualization of the SARS-CoV-2 genome sequences and analyses, the +UCSC Genome Browser for SARS-Cov-2, +by incorporating relevant biomedical datasets such as single-cell lung gene expression into the +UCSC Cell Browser, and by creating data tracks +of +COVID-19 annotations in our Human Genome Browsers.
-A manuscript describing this work, +A manuscript describing The UCSC SARS-CoV-2 Genome Browser, was published in the September 9 issue of Nature Genetics.
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