dc28e7eaba410716bba6a5f86c78a11b9e817a61 dschmelt Mon Oct 5 15:04:15 2020 -0700 Small link fixes for dbVar refs #25423 diff --git src/hg/makeDb/trackDb/human/dbVarCommon.html src/hg/makeDb/trackDb/human/dbVarCommon.html index e22e470..015acbf 100644 --- src/hg/makeDb/trackDb/human/dbVarCommon.html +++ src/hg/makeDb/trackDb/human/dbVarCommon.html @@ -1,102 +1,110 @@ <h2>Description</h2> <p> This track displays common copy number genomic variations from <a target=_blank href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186/">nstd186 (NCBI Curated Common Structural Variants)</a>, divided into subtracks according to population and source of original submission. </p> <p> This curated dataset of all structural variants in dbVar includes variants from <b>gnomAD</b>, <b>1000 Genomes Phase 3</b>, and <b>DECIPHER</b> (dbVar studies <a target=_blank href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd166/">nstd166</a>, <a target=_blank href="https://www.ncbi.nlm.nih.gov/dbvar/studies/estd219/">estd219</a>, and <a target=_blank href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd183/">nstd183</a>, respectively). </p> <p> It only includes copy number gain, copy number loss, copy number variation, duplications, and deletions (including mobile element deletions), that are part of a study with at least 100 samples, include allele frequency data, and have an allele frequency of >=0.01 in at least one population. </p> <p> For more information on the number of variant calls and latest statistics for nstd186 see <a target=_blank href="https://www.ncbi.nlm.nih.gov/dbvar/content/common_summary/">Summary of nstd186</a> (NCBI Curated Common Structural Variants). </p> <p> There are six subtracks in this track set: </p> <p> <ul> <li><b>NCBI Curated Common SVs: African -</b> <a href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186">Variants</a> with AF >= 0.01 for African Population.</li> <li><b>NCBI Curated Common SVs: European -</b> <a href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186">Variants</a> with AF >= 0.01 for European Population.</li> <li><b>NCBI Curated Common SVs: all populations -</b> <a href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186">Variants</a> with AF >= 0.01 for Global Population.</li> <li><b>NCBI Curated Common SVs: all populations from gnomAD - </b> <a href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186">Variants</a> with AF >= 0.01 from gnomAD Structural Variants.</li> <li><b>NCBI Curated Common SVs: all populations from 1000 Genomes - </b> <a href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186">Variants</a> with AF >= 0.01 from 1000 Genomes Consortium Phase 3 Integrated SV.</li> <li><b>NCBI Curated Common SVs: all populations from DECIPHER -</b> <a href="https://www.ncbi.nlm.nih.gov/dbvar/studies/nstd186">Variants</a> with AF >= 0.01 from DECIPHER Consensus CNVs.</li> </ul> </p> <h2>Display Conventions and Configuration</h2> Items in all subtracks follow the same conventions: items are colored by variant type, and are based on the dbVar colors described in the <a target="_blank" href="https://www.ncbi.nlm.nih.gov/dbvar/content/overview/">dbVar Overview page</a>. <b><font color="red">Red</font></b> for copy number loss or deletion, <b><font color="blue">blue</font></b> for copy number gain or duplication, and <b><font color="#662180">violet</font></b> for copy number variation. </p> <p> <b>Mouseover</b> on items indicates genes affected, size, variant type, and allele frequencies (AF). All tracks can be filtered according to the <b>Variant Size</b> and <b>Variant Type</b>. </p> <h2>Data Access</h2> The raw data can be explored interactively with the -<a href="https://genome.ucsc.edu/cgi-bin/hgTables">Table Browser</a>, or the -<a href="https://genome.ucsc.edu/cgi-bin/hgIntegrator">Data Integrator</a>. For automated analysis, +<a href="../../hgTables">Table Browser</a>, or the +<a href="../../hgIntegrator">Data Integrator</a>. For automated analysis, the data may be queried from our -<a href="https://genome.ucsc.edu/goldenPath/help/api.html">REST API</a>. The data can also be found -directly from the dbVar nstd186 <a target=_blank -href="https://www.ncbi.nlm.nih.gov/dbvar/content/common_summary/#data_access">data access</a>, as -well as in the <a href="https://genome.ucsc.edu/cgi-bin/hgHubConnect?hgsid=910263067_X3tU6DiJPhKMr71o1h9Zj2K5XQ4u" ->dbVar Track Hub</a>, where additional subtracks are included. For questions about dbVar track -data, please contact <em>dbvar@ncbi.nlm.nih.gov</em>. +<a href="../../goldenPath/help/api.html">REST API</a>. </p> +<p>The data can also be found directly from the <a target=_blank +href="https://www.ncbi.nlm.nih.gov/dbvar/content/common_summary/#data_access">dbVar +nstd186 data access</a>, as well as in the +<a href="hgHubConnect?hubUrl= +https://ftp.ncbi.nlm.nih.gov/pub/dbVar/sandbox/dbvarhub/hub.txt&hgHub_do_redirect=on"> +dbVar Track Hub</a>, where additional subtracks are included. For questions about +dbVar track data, please contact <A HREF="mailto:dbvar@ncbi. +nlm.nih.gov"> +dbvar@ncbi.nlm.nih.gov +</A>. +<!-- above address is dbvar at ncbi.nlm.nih.gov --> +</p> + <h2>Credits</h2> <p> Thanks to the dbVAR team at NCBI, especially John Lopez and Timothy Hefferon for technical coordination and consultation, and to Christopher Lee, Anna Benet-Pages, and Daniel Schmelter, of the Genome Browser team for engineering the track display. </p> <h2>References</h2> <p> Lappalainen I, Lopez J, Skipper L, Hefferon T, Spalding JD, Garner J, Chen C, Maguire M, Corbett M, Zhou G <em>et al</em>. <a href="https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/gks1213" target="_blank"> DbVar and DGVa: public archives for genomic structural variation</a>. <em>Nucleic Acids Res</em>. 2013 Jan;41(Database issue):D936-41. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/23193291" target="_blank">23193291</a>; PMC: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3531204/" target="_blank">PMC3531204</a> </p>