40afe6a0c034dd7d9d7c8c2f929c420f447067ee abenetpa Mon Oct 19 07:38:36 2020 -0700 corrected sentence dec page refs #26330 diff --git src/hg/makeDb/trackDb/human/clinvar.html src/hg/makeDb/trackDb/human/clinvar.html index 6adefd8..ff5b936 100644 --- src/hg/makeDb/trackDb/human/clinvar.html +++ src/hg/makeDb/trackDb/human/clinvar.html @@ -75,34 +75,34 @@ </p> <p> Entries in the <b>ClinVar SNVs and ClinVar Interpretations tracks</b> are colored by <b>clinical significance</b>: <ul> <li><b><font color="d20000">red for pathogenic</font></b></li> <li><b><font color="000088">dark blue for variant of uncertain significance</font></b></li> <li><B><font color="#00d200">green for benign</font></b></li> <li><B><font color="#888">dark grey for not provided</font></b></li> <li><B><font color="#8979D4">light blue for conflicting</font></b></li> </ul> </p> <p> -Variants in the <b>ClinVar Interpretations track</b> are sorted out according to the variant -classification of each single submission (P: Pathogenic, LP: Likely Pathogenic, VUS: Variant of +The variants in the <b>ClinVar Interpretations track</b> are sorted by the variant +classification of each submission (P: Pathogenic, LP: Likely Pathogenic, VUS: Variant of Unknown Significance, LB: Likely Benign, B: Benign, OTH: Others), the size of the bead represents -the submissions count at that genomic position. +the number of submissions at that genomic position. Hovering on the track items shows the genomic variations which start at that position and the number of individual submissions with that classification. The details page lists all rated submissions from ClinVar, with specific details to the interpretation of the clinical or functional significance of each variant in relation to a condition. Interpretation is at variant-level, not at case (or patient-specific) level. </p> <p> More information about using and understanding the ClinVar data can be found <a target="_blank" href="https://www.ncbi.nlm.nih.gov/clinvar/docs/faq/">here</a>. </p> <p> For the human genome version hg19: the hg19 genome released by UCSC in 2009 had a mitochondrial genome "chrM" that was not the same as the one later used for most