0c85ef2a7ae60b49c2ce4f3175a9f3a54cda412f
kate
  Mon Nov 9 13:56:11 2020 -0800
Restore lost Description section, and remove section about multi-region. refs #26351

diff --git src/hg/makeDb/trackDb/human/covidMuts.html src/hg/makeDb/trackDb/human/covidMuts.html
index 22cb9a3..fbf2275 100644
--- src/hg/makeDb/trackDb/human/covidMuts.html
+++ src/hg/makeDb/trackDb/human/covidMuts.html
@@ -1,22 +1,35 @@
-<h2>Display Conventions</h2>
+<h2>Description</h2>
+<p>
+This track shows variants associated with monogenic congenital defects of immunity to the <b>SARS-CoV-2</b> 
+virus identified by the <a target=_blank 
+href="https://www.covidhge.com/">COVID Human Genetic Effort</a>. This international consortium aims
+to detect rare or common monogenic inborn immunity errors (IEI) underlying severe forms of COVID-19
+in previously healthy individuals, as well as rare or common monogenic variations that make certain
+individuals resistant to infection by SARS-CoV2 virus despite repeated exposure.
+</p>
 <p>
-Unlike a regular genome browser track, the <b>COVID-19 Immunity Variants</b> track displays all
-affected genes in <a href="https://genome.ucsc.edu/goldenPath/help/multiRegionHelp.html">multi-region view</a>,
-showing the variants within the coordinates of the gene, but hiding all the intergenic bases. To
-return to the default Genome Browser view, click on the "-" button next to the "region" box.
+The major feature of the small set of  variants in this track is that they are functionally tested
+to be <b>deleterious</b> and genetically tested to be <b>disease-causing</b>. Specifically,
+rare variants were predicted to be loss-of-function (LOF) at 13 human loci known to govern
+TLR3- and IRF7-dependent type I interferon (IFN) immunity to influenza virus in patients with
+life-threatening COVID-19 pneumonia, relative to subjects with asymptomatic or benign infection.
+These genetic defects display incomplete penetrance for influenza respiratory distress and only
+manifested clinically upon infection with the more virulent SARS-CoV-2.
 </p>
+
+<h2>Display Conventions</h2>
 <p>
 Only eight genes and few variants are contained in this track. Use the links in the table to
 browse the gene of interest:
 </p>
 
 <table class="stdTbl">
   <tr>
     <th>Gene Name</th>
     <th>Human GRCh37/hg19 Assembly</th>
     <th>Human GRCh38/hg38 Assembly</th>
   </tr>
   <tr>
    <td>TLR3</td>
     <td><a href="../cgi-bin/hgTracks?db=hg19&covidHgeMuts=pack&position=chr4:186990309-187006252">
 chr4:186990309-187006252</a></td>