1d8f618eb675164f82954223744046e2ea2bec3d jnavarr5 Tue Dec 29 15:02:37 2020 -0800 Replacing a word. refs #20314 diff --git src/hg/htdocs/goldenPath/history.html src/hg/htdocs/goldenPath/history.html index 57aa222..54b4c6d 100755 --- src/hg/htdocs/goldenPath/history.html +++ src/hg/htdocs/goldenPath/history.html @@ -26,31 +26,31 @@ <li><a href="#primer">UCSC Genome Research Primer</a></li> <ul class="gbsNoBullet"> <li><a href="#comparative">Comparative Genomics</a></li> <li><a href="#health">Possibilities for Health</a></li> </ul> </ul> <a name="overview"></a> <h2>Genome Browser Overview</h2> <p> The UCSC Genome Browser is a web-based tool serving as a multi-powered microscope that allows researchers to view all 23 chromosomes of the human genome at any scale from a full chromosome down to an individual nucleotide. The browser integrates the work of countless scientists in laboratories worldwide, including work generated at UCSC, in an interactive, graphical display.</p> <a name="genomic"></a> -<h3>The Genomic Kaleidoscope</h3> +<h3>The Genomic Microscope</h3> <p> Zoomed out, the coarse-level view of the genome shows early chromosome maps as determined by electron microscopy, then the browser drills down to levels of increasing detail, focusing first on chromosome bands. The next level detail zooms in on gene clusters, showing known and predicted genes near one another on the chromosome. Zooming in further to view a single gene shows the components of genes, the introns and exons. Finally, the browser allows researchers to view the nucleotides-the As, Cs, Gs, and Ts that make up the genome alphabet. Not only does the browser show the genome sequence, but it also delineates known areas of the genome and offers supplementary information about the genes-in effect, providing the word breaks and punctuation.</p> <p> Genome sequences are difficult to read because they consist of letter strings with no breaks or punctuation. The example below contains 7 different letters (genomes contain only 4). Can you understand what it is saying? (Line borrowed from the movie, <em><a href = "https://en.wikipedia.org/wiki/Charly" target = _blank>Charly</a></em>.)</p> <pre>