0214da4a034d28253fffea4589e25600c5505348 jnavarr5 Tue Jan 26 16:02:30 2021 -0800 Adding a link to the Single Cell Browser as per Jim's request, refs #20314 diff --git src/hg/htdocs/goldenPath/history.html src/hg/htdocs/goldenPath/history.html index 0c320b7..6327567 100755 --- src/hg/htdocs/goldenPath/history.html +++ src/hg/htdocs/goldenPath/history.html @@ -100,30 +100,32 @@ fully understanding the workings of the human genome, a project that will occupy science and medicine for many years. The browser platform has multiple potential uses that can aid in disease prevention, diagnostics, and the search for cures. The usefulness of the UCSC Genome Browser lead to spin-offs, or Genome Browser mirrors, such as the following:</p> <ul> <li><a href="https://news.ucsc.edu/2008/05/2242.html" target="_blank">The HIV Data Browser</a></li> <li><a href="https://xena.ucsc.edu/welcome-to-ucsc-xena/" target="_blank">The UCSC Cancer Genomics Browser</a></li> <li><a href="../ENCODE/" target="_blank">The data collection center for the international ENCODE project</a></li> <li><a href="../ebolaPortal/" target="_blank">The UCSC Ebola Virus Genome Browser</a></li> <li><a href="../covid19.html" target="_blank">The UCSC SARS-CoV-2 coronavirus Browser</a></li> + <li><a href="../singlecell.html" + target="_blank">The Single Cell Browser</a></li> </ul> <a name="race"></a> <h2>Human Genome Project — The Race</h2> <p> In December 1999, the <a href="https://www.genome.gov/human-genome-project" target="_blank">International Human Genome Project (IHGP)</a> came to UC Santa Cruz when Eric Lander, the director of the Whitehead sequencing center (Whitehead Institute/MIT Center for Genome Research), invited David Haussler to help annotate the human genome. In particular, Lander wanted help in discovering the locations of the genes, which make up only approximately 1.5% of the sequence. Haussler had previously applied a mathematical technique known as hidden Markov models (HMMs) to the task of computer gene-finding. This application of HMMs had quickly become the dominant gene-finding methodology and was used successfully on the <i>Drosophila melanogaster</i> (fruit fly) genome. But the process requires intact long-range genomic sequence to find the genes and the human genome sequence was in many small pieces.</p>