2065b8b9a610a9fe59fdb593aabe88c76962c168 jnavarr5 Thu Feb 25 14:30:45 2021 -0800 Replacing double quotes with the HTML entity, refs #18492 diff --git src/hg/makeDb/trackDb/human/caddSuper.html src/hg/makeDb/trackDb/human/caddSuper.html index d159e19..cbc05cc 100644 --- src/hg/makeDb/trackDb/human/caddSuper.html +++ src/hg/makeDb/trackDb/human/caddSuper.html @@ -22,37 +22,37 @@ Finally, CADD scores of complex trait-associated variants from genome-wide association studies (GWAS) are significantly higher than matched controls and correlate with study sample size, likely reflecting the increased accuracy of larger GWAS.

Display Conventions and Configuration

There are six subtracks of this track: four for every possible single nucleotide mutation, one for insertions and one for deletions. All subtracks show the CADD Phred score on mouseover.

Single nucleotide variants (SNV): For SNVs, at every genome position, there are three values per position, one for every possible -nucleotide mutation. The fourth value, "no mutation", e.g. A to A, is always +nucleotide mutation. The fourth value, "no mutation", e.g. A to A, is always set to zero.
When using this track, please zoom in until you can see every basepair at the top of the display. Otherwise, there are several nucleotides under your mouse cursor per pixel and instead of an actual score, the tooltip text can only show the average score of all nucleotides under the cursor, which is indicated by -the prefix "~" in the mouseover and averages of scores are not useful for any +the prefix "~" in the mouseover and averages of scores are not useful for any application of CADD.

Insertions and deletions:: Scores are also shown on mouseover for a set of insertions and deletions. On hg38, the set has been obtained from Gnomad3. On hg19, the set of indels has been obtained from various sources (gnomAD2, ExAC, 1000 Genomes, ESP). If your insertion or deleletion of interest is not in the track, you will need to use CADD's Online scoring tool to obtain them.

Data access

CADD scores are freely available for all non-commercial applications from the CADD website. For commercial applications, see the license instructions there.