50d9c48ac1cbb26bfbbb5e132f69d5391d782f7d jnavarr5 Wed Mar 3 08:08:34 2021 -0800 Removing an 's' from deletions, refs #18492 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index 82263fa..9b7e655 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -48,31 +48,31 @@ </div> </div> </div> <!-- ============= 2021 archived news ============= --> <a name="2021"></a> <a name="030221"></a> <h2>Mar. 02, 2021 CADD Scores now available for hg19 and hg38</h2> <p> We are happy to announce the release of a new track for human assemblies, <a href="../cgi-bin/hgTrackUi?db=hg19&chr=chrX">hg19</a> and <a href="../cgi-bin/hgTrackUi?db=hg38&chr=chrX">hg38</a>. The new track shows <a href="https://cadd.gs.washington.edu/" target="_blank">Combined Annotation Dependent Depletion (CADD)</a> scores for each base in the genome and corresponds to the v1.6 developmental release. CADD is a tool for scoring the deleteriousness of single nucleotide variants as well as -insertion/deletions variants in the human genome. CADD scores strongly correlate with allelic +insertion/deletion variants in the human genome. CADD scores strongly correlate with allelic diversity, pathogenicity of both coding and non-coding variants, experimentally measured regulatory effects, and also highly rank causal variants within individual genome sequences. Finally, CADD scores of complex trait-associated variants from genome-wide association studies (GWAS) are significantly higher than matched controls and correlate with study sample size, likely reflecting the increased accuracy of larger GWAS.</p> <p>The supertrack consists of the following tracks:</p> <ul> <li><strong>CADD</strong> (composite track) <ul> <li>Mutation: A</li> <li>Mutation: C</li> <li>Mutation: G</li> <li>Mutation: T</li> </ul>