be4311c07e14feb728abc6425ee606ffaa611a58
markd
  Fri Jan 22 06:46:58 2021 -0800
merge with master

diff --git src/hg/makeDb/trackDb/human/trackDb.ra src/hg/makeDb/trackDb/human/trackDb.ra
index 1d9e9fb..7acb248 100644
--- src/hg/makeDb/trackDb/human/trackDb.ra
+++ src/hg/makeDb/trackDb/human/trackDb.ra
@@ -20,30 +20,33 @@
 # GeneHancer from Weizmann labs
 include trackDb.geneHancer.ra
 
 # NCBI ClinVar
 include trackDb.clinvar.ra
 
 # NCBI dbVar
 include trackDb.dbVar.ra
 
 # ClinGen
 include trackDb.clinGen.ra
 
 # Genome In a Bottle
 include trackDb.giab.ra
 
+# CADD scores
+include cadd.ra alpha
+
 track cytoBandIdeo
 shortLabel Chromosome Band (Ideogram)
 longLabel Chromosome Bands Localized by FISH Mapping Clones (for Ideogram)
 group map
 visibility dense
 type bed 4 +
 
 track cytoBand
 shortLabel Chromosome Band
 longLabel Chromosome Bands Localized by FISH Mapping Clones
 group map
 visibility hide
 type bed 4 +
 
 track hiSeqDepth
@@ -119,31 +122,30 @@
 visibility hide
 type bigBed 9 +
 itemRgb on
 tableBrowser off
 bigDataUrl /gbdb/$D/decipher/decipherCnv.bb
 url https://decipher.sanger.ac.uk/patient/$$
 urlLabel Decipher Patient View:
 filter.size 0
 filterByRange.size on
 filterLimits.size 2:170487333
 filterValues.variant_class Amplification,Copy-Number Gain,Deletion,Duplication,Duplication/Trip
 filterValues.pathogenicity Benign,Likely Benign,Likely Pathogenic,Pathogenic,Uncertain,Unknown
 mergeSpannedItems on
 searchIndex name
 mouseOverField _mouseOver
-pennantIcon Updated red ../goldenPath/newsarch.html#101320 "Updated Oct. 13, 2020"
 
 searchTable decipher
 searchMethod exact
 searchType bigBed
 release alpha,beta
 
 track decipherSnvs
 shortLabel DECIPHER SNVs
 longLabel DECIPHER: Chromosomal Imbalance and Phenotype in Humans (SNVs)
 group phenDis
 visibility hide
 color 0,0,0
 type bed 4
 tableBrowser off decipherSnvsRaw
 prevExonText Left edge
@@ -188,50 +190,30 @@
 
         track avada
         shortLabel Avada Variants
         longLabel Avada Variants extracted from full text publications
         visibility dense
         type bigBed 9 +
         bigDataUrl /gbdb/$D/bbi/avada.bb
         noScoreFilter on
         exonNumbers off
         #itemRgb on
         dataVersion release 1
         parent varsInPubs pack
         urls pmid="https://www.ncbi.nlm.nih.gov/pubmed/$$" doi="https://doi.org/$$" ensId="http://grch37.ensembl.org/Homo_sapiens/Gene/Summary?g=$$" entrezs="https://www.ncbi.nlm.nih.gov/gene/$$" refSeq="https://www.ncbi.nlm.nih.gov/nuccore/$$"
         mouseOverField _mouseOver
 
-track pathoPred
-type bigWig
-longLabel Pathogenicity predictions
-shortLabel Pathogenicity
-color 112,172,192
-visibility hide
-superTrack on
-group phenDis
-
-        track cadd
-        type bigWig
-        longLabel CADD scores version 1.4
-        viewLimits 0:30
-        color 100,130,160
-        bigDataUrl /gbdb/$D/bbi/CADD-v1.4.bw
-        viewLimitsMax 0:100
-        shortLabel CADD
-        visibility full
-        parent pathoPred on
-
 track caseControl
 compositeTrack on
 shortLabel Case Control
 longLabel Case Control Consortium
 group phenDis
 visibility hide
 type chromGraph
 minMax 0,15
 linesAt 5,10
 
     track cccTrendPvalBd
     parent caseControl
     shortLabel CCC Bipolar Dis
     longLabel Case Control Consortium Bipolar Disorder Trend -log10 P-value
     priority 1
@@ -3158,78 +3140,78 @@
 shortLabel sno/miRNA
 longLabel C/D and H/ACA Box snoRNAs, scaRNAs, and microRNAs from snoRNABase and miRBase
 group genes
 visibility hide
 color 200,80,0
 type bed 8 +
 noScoreFilter .
 urlLabel Laboratoire de Biologie Moleculaire Eucaryote:
 url http://www-snorna.biotoul.fr/plus.php?id=$$
 url2Label miRBase:
 #url2 http://microrna.sanger.ac.uk/cgi-bin/sequences/mirna_entry.pl?id=$$
 url2 http://www.mirbase.org/cgi-bin/query.pl?terms=$$
 dataVersion miRBase Release 13.0 (March 2009) and snoRNABase Version 3
 
 track lrgBigPsl
-shortLabel LRG Transcripts (RM 24672)
-longLabel Locus Reference Genomic (LRG) Fixed Transcript Annotations (RedMine 24672)
+shortLabel LRG Transcripts
+longLabel Locus Reference Genomic (LRG) Fixed Transcript Annotations
 group genes
 visibility hide
 type bigPsl
-mouseOverField mouseOver
+html lrgTranscriptAli
+mouseOver ${name}: ${ncbiTranscript} ${ensemblTranscript} ${ncbiProtein} ${ensemblProtein} ${geneName}
 skipFields mouseOver
 skipEmptyFields on
 urls ncbiTranscript=https://www.ncbi.nlm.nih.gov/nuccore/$$ ensemblTranscript=http://www.ensembl.org/Multi/Search/Results?site=ensembl_all;q=$$ ncbiProtein=https://www.ncbi.nlm.nih.gov/protein/$$ ensemblProtein=http://www.ensembl.org/Multi/Search/Results?site=ensembl_all;q=$$
-cdsTable lrgCds
-cdnaTable lrgCdna
-pepTable lrgPep
 altColor 127,127,127
 baseColorDefault genomicCodons
 baseColorUseSequence lfExtra
-baseColorUseCds table lrgCds
 indelDoubleInsert on
 indelPolyA on
 indelQueryInsert on
 showDiffBasesAllScales .
 showDiffBasesMaxZoom 10000.0
 showCdsAllScales .
 showCdsMaxZoom 10000.0
 color 54,125,29
 urlLabel Link to LRG transcript:
 url http://ftp.ebi.ac.uk/pub/databases/lrgex/$$.xml#transcripts_anchor
+bigDataUrl /gbdb/$D/bbi/lrgBigPsl.bb
+release alpha
 
 track lrgTranscriptAli
 shortLabel LRG Transcripts
 longLabel Locus Reference Genomic (LRG) Fixed Transcript Annotations
 group genes
 visibility hide
 type psl .
 cdsTable lrgCds
 cdnaTable lrgCdna
 pepTable lrgPep
 baseColorDefault diffCodons
 baseColorUseCds table lrgCds
 baseColorUseSequence table lrgCdna
 indelDoubleInsert on
 indelQueryInsert on
 showDiffBasesAllScales .
 showDiffBasesMaxZoom 10000.0
 showCdsAllScales .
 showCdsMaxZoom 10000.0
 color 54,125,29
 urlLabel Link to LRG transcript:
 url http://ftp.ebi.ac.uk/pub/databases/lrgex/$$.xml#transcripts_anchor
+release beta,public
 
 track affyHuEx1
 shortLabel Affy HuEx 1.0
 longLabel Affymetrix Human Exon 1.0 Probe Sets
 group expression
 visibility hide
 url http://www.affymetrix.com/analysis/netaffx/exon/probe_set.affx?pk=1:$$
 urlLabel Netaffx Link:
 useScore 1
 type bed 6 .
 
 track affyHumanExon
 shortLabel Affy All Exon
 longLabel Affymetrix All Exon Chips
 group expression
@@ -3689,31 +3671,30 @@
         type bigBed 12 +
         release alpha
         bigDataUrl /gbdb/$D/bbi/cancerMutations/BRCA.bb
         urls case_id=https://portal.gdc.cancer.gov/cases/$$
         parent cancerMutations
 
 track lovdComp
 shortLabel LOVD Variants
 longLabel Leiden Open Variation Database Public Variants
 group phenDis
 visibility hide
 compositeTrack on
 type bigBed 4 +
 tableBrowser off lovdComp
 html lovdComp
-pennantIcon Updated red ../goldenPath/newsarch.html#101320 "Updated Oct. 13, 2020"
 
         track lovdShort
         shortLabel LOVD Variants < 50 bp
         longLabel Leiden Open Variation Database, short < 50 bp variants
         group phenDis
         visibility hide
         urls id="http://varcache.lovd.nl/redirect/$$"
         noScoreFilter on
         bigDataUrl /gbdb/$D/lovd/lovd.$D.short.bb
         parent lovdComp
 
         track lovdLong
         type bigBed 9 +
         shortLabel LOVD Variants >= 50 bp
         longLabel Leiden Open Variation Database Public Variants, long >= 50 bp variants
@@ -3726,30 +3707,31 @@
         mergeSpannedItems on
 
 track hgmd
 shortLabel HGMD Variants
 longLabel Human Gene Mutation Database Public Variants
 group phenDis
 visibility hide
 itemRgb on
 type bigBed 9 .
 url http://www.hgmd.cf.ac.uk/ac/gene.php?gene=$P&accession=$p
 urlLabel Link to HGMD
 mouseOverField variantType
 tableBrowser off hgmd
 noScoreFilter on
 maxItems 1000
+pennantIcon Updated red
 
 track snpedia
 shortLabel SNPedia
 longLabel SNPedia
 group phenDis
 visibility hide
 color 50,0,100
 type bed 4
 compositeTrack on
 
     track snpediaText
     parent snpedia
     shortLabel SNPedia with text
     longLabel SNPedia pages with manually typed text
     color 50,0,100
@@ -4064,36 +4046,45 @@
 searchType bed
 termRegex Hs\.[0-9]+
 searchPriority 20
 
 searchTable uniGene_3
 searchType psl
 termRegex Hs\.[0-9]+
 searchPriority 20
 
 searchTable HInvGeneMrna
 searchMethod exact
 searchType psl
 termRegex HIT[0-9]{9,9}
 searchPriority 50
 
+searchTable lrgBigPsl
+searchMethod exact
+searchType bigBed
+termRegex LRG_[0-9]+t[0-9]+
+semiShortCircuit 1
+searchPriority 50
+release alpha
+
 searchTable lrgTranscriptAli
 searchMethod exact
 searchType psl
 termRegex LRG_[0-9]+t[0-9]+
 semiShortCircuit 1
 searchPriority 50
+release beta,public
 
 searchName lrgTranscriptAliNoTNum
 searchTable lrgTranscriptAli
 query select tName, tStart, tEnd, qName from %s where qName like '%st%%'
 termRegex LRG_[0-9]+
 dontCheck LRG_[0-9]+t[0-9+]
 semiShortCircuit 1
 searchPriority 50
 
 searchTable acescan
 searchMethod fuzzy
 searchType genePred
 termRegex .*_pred\.[0-9]+
 searchPriority 50
 
@@ -5082,31 +5073,30 @@
 include decode.rmap.ra
 
 #geneReviews track
 track geneReviews
 shortLabel GeneReviews
 longLabel GeneReviews
 group  phenDis
 visibility hide
 color 0, 80, 0
 type bigBed 9 +
 bigDataUrl /gbdb/$D/geneReviews/geneReviews.bb
 mouseOver $name disease(s): $diseases
 html geneReviews
 url https://www.ncbi.nlm.nih.gov/books/NBK1116/?term=$$
 noScoreFilter on
-pennantIcon Updated red ../goldenPath/newsarch.html#101320 "Updated Oct. 13, 2020"
 
 searchName geneReviews
 searchTable geneReviews
 searchType bed
 searchPriority 50
 xrefTable geneReviewsDetail
 xrefQuery select geneSymbol,grTitle from %s where grTitle like '%%%s%%'
 searchBoth on
 
 searchTable dgv
 searchType bed
 searchPriority 50
 termRegex (dgv_|[en]ss?v)[0-9]+
 
 searchTable coriellDelDup