098e7866ab59c5c6b0c4c77919350d637894d113 markd Wed Apr 28 00:38:42 2021 -0700 transMap V6 diff --git src/hg/makeDb/trackDb/transMapV6.html src/hg/makeDb/trackDb/transMapV6.html new file mode 100644 index 0000000..3fa6f12 --- /dev/null +++ src/hg/makeDb/trackDb/transMapV6.html @@ -0,0 +1,25 @@ +
+These tracks contain cDNA and gene alignments produced by +the TransMap cross-species alignment algorithm +from other vertebrate species in the UCSC Genome Browser. +For closer evolutionary distances, the alignments are created using +syntenically filtered LASTZ or BLASTZ alignment chains, resulting +in a prediction of the orthologous genes in $organism. For more distant +organisms, reciprocal best alignments are used. +
+ +TransMap maps genes and related annotations in one species to another +using synteny-filtered pairwise genome alignments (chains and nets) to +determine the most likely orthologs. For example, for the mRNA TransMap track +on the human assembly, more than 400,000 mRNAs from 25 vertebrate species were +aligned at high stringency to the native assembly using BLAT. The alignments +were then mapped to the human assembly using the chain and net alignments +produced using BLASTZ, which has higher sensitivity than BLAT for diverged +organisms. ++Compared to translated BLAT, TransMap finds fewer paralogs and aligns more UTR +bases. +
+