2451a31c5dda55d37d1a5b2aa74d47679a5e232e
jnavarr5
  Thu May 20 17:07:09 2021 -0700
Making changes to vaccines announcement from code review, CR #27574

diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html
index 6b1ec91..863f305 100755
--- src/hg/htdocs/goldenPath/newsarch.html
+++ src/hg/htdocs/goldenPath/newsarch.html
@@ -60,32 +60,34 @@
 to the coronavirus genome:
 </p>
 <ol>
   <li>
     The BioNTech/Pfizer BNT-162b2 sequence as published by the World Health Organization (WHO)</li>
   <li>
     The reconstructed BioNTech/Pfizer BNT-162b2 RNA as sequenced by the
     <a href="https://firelab.sites.stanford.edu/" target="_blank">Andrew Fire lab</a>, Stanford
     University School of Medicine</li>
   <li>
     The Moderna mRNA-1273 sequence as sequenced by the
     <a href="https://firelab.sites.stanford.edu/" target="_blank">Andrew Fire lab</a>, Stanford
     University School of Medicine</li>
 </ol>
 <p>
-The protein encoded by the three sequences has two AA substitutions compared to the SARS-CoV-2 S
-glycoprotein. Variations: S:K986P and S:V987P in the vaccine sequence. See also:
+The protein encoded by the three sequences has two amino acid substitutions compared to the
+SARS-CoV-2 S glycoprotein. These vaccines include two variations compared to the reference Spike
+sequence to stabilize the shape into a pre-infection structure that delivers a better immune
+response, S:K986P and S:V987P. See also:
 <a href="https://cen.acs.org/pharmaceuticals/vaccines/tiny-tweak-behind-COVID-19/98/i38"
 target="_blank">The tiny tweak behind COVID-19 vaccines</a>. More information about this track can
 be found on the <a href="../cgi-bin/hgTrackUi?db=wuhCor1&c=NC_045512v2&g=vaccines">description
 page</a>.
 <p>
 We want to thank the <a href="https://twitter.com/Fire__Lab" target="_blank">Andrew Fire lab</a>,
 Stanford University School of Medicine for providing the sequencing data of these vaccines. We also
 want to thank Hiram Clawson and Jairo Navarro for the creation and release of this track.</p>
 
 <a name="050421"></a>
 <h2>May. 04, 2021 &nbsp;&nbsp; New Genome Browser: Rat, rn7 (<em>Rattus norvegicus</em>)</h2>
 <p>
 A genome browser is now available for the <em>Rattus norvegicus</em> assembly released in Nov. 2020 by the
 <a href="https://www.darwintreeoflife.org/" target="_blank"> Darwin Tree of Life Project</a> at the
 <a href="https://www.sanger.ac.uk/" target="_blank"> Wellcome Sanger Institute</a> (mRatBN7.2).