The SARS-CoV-2 coronavirus emerged in December 2019 as a novel human pathogen causing a severe acute respiratory syndrome (COVID-19). The disease spread rapidly worldwide and was declared a pandemic by the World Health Organization on March 11, 2020.
Genome sequencing of thousands of viral samples has helped researchers study mechanisms of infection, transmission and response of the human immune system. @@ -33,31 +33,33 @@ of COVID-19 annotations in our Human Genome Browsers. These annotations can further understanding of the human genetic determinants of infection susceptibility, disease severity, and outcomes.
Since the beginning of SARS-CoV-2 circulation in humans, the viral genome has been accummulating mutations. Mutations identified as important medically and epidemiologically are displayed in SARS-Cov-2 browser tracks Variants of Concern and Spike Mutations. Investigations of antibody resistance of viral mutations are available in the Antibody Escape track -collection. +collection. The alignment of the Pfizer and Moderna mRNA vaccine sequences to the SARS-CoV-2 genome +can be viewed using the +Vaccines track.
See our SARS-CoV-2 introduction page for an overview of the resources offered. A manuscript describing The UCSC SARS-CoV-2 Genome Browser was also published in the September 9, 2020 issue of Nature Genetics.
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