35bbdbb24ededa5368e4f3570af0b92d4c5ef6fb jnavarr5 Tue May 11 10:07:35 2021 -0700 Adding the release of the Vaccines track to the COVID landing page, refs #27312 diff --git src/hg/htdocs/covid19.html src/hg/htdocs/covid19.html index 4a9e48e..6a1cd30 100755 --- src/hg/htdocs/covid19.html +++ src/hg/htdocs/covid19.html @@ -1,24 +1,24 @@ <!DOCTYPE html> <!--#set var="TITLE" value="COVID-19 Research at UCSC" --> <!--#set var="ROOT" value="." --> <!--#include virtual="$ROOT/inc/gbPageStart.html"--> <h1>COVID-19 Research at UCSC <span> <font size=-1 style="padding-left: 10px; padding-right: 10px; margin-left: 15px;"> -<a href="#news">Updated: March 11, 2021</a></font></span></h1> +<a href="#news">Updated: May 11, 2021</a></font></span></h1> <div class="row"> <div class="col-md-6"> <p> The SARS-CoV-2 coronavirus emerged in December 2019 as a novel human pathogen causing a severe acute respiratory syndrome (COVID-19). The disease spread rapidly worldwide and was <A TARGET="_BLANK" HREF="https://www.who.int/dg/speeches/detail/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-19---11-march-2020"> declared a pandemic by the World Health Organization</a> on March 11, 2020. </p> <p> Genome sequencing of thousands of viral samples has helped researchers study mechanisms of infection, transmission and response of the human immune system. @@ -33,31 +33,33 @@ of <a target="_blank" href="#covidHgiGwas">COVID-19 annotations in our Human Genome Browsers</a>. These annotations can further understanding of the human genetic determinants of infection susceptibility, disease severity, and outcomes. </p> <p> Since the beginning of SARS-CoV-2 circulation in humans, the viral genome has been accummulating mutations. Mutations identified as important medically and epidemiologically are displayed in SARS-Cov-2 browser tracks <a target="_blank" href="/cgi-bin/hgTrackUi?db=wuhCor1&g=variantMuts">Variants of Concern</a> and <a target="_blank" href="/cgi-bin/hgTrackUi?db=wuhCor1&g=spikeMuts">Spike Mutations</a>. Investigations of antibody resistance of viral mutations are available in the <a target="_blank" href="/cgi-bin/hgTrackUi?db=wuhCor1&g=abEscape">Antibody Escape</a> track -collection. +collection. The alignment of the Pfizer and Moderna mRNA vaccine sequences to the SARS-CoV-2 genome +can be viewed using the +<a target="_blank" href="/cgi-bin/hgTrackUi?db=wuhCor1&c=NC_045512v2&g=vaccines">Vaccines</a> track. </p> <p> See our <a href="/goldenPath/help/covidBrowserIntro.html" target="_blank"> SARS-CoV-2 introduction page</a> for an overview of the resources offered. A manuscript describing <a href="https://www.nature.com/articles/s41588-020-0700-8" target="_blank"> The UCSC SARS-CoV-2 Genome Browser</a> was also published in the September 9, 2020 issue of <em>Nature Genetics</em>. </p> </div> <div class="col-md-6"> <img class="text-center" alt="COVID-19 transmission as of May 30, 2020, from Nextstrain" src="/images/covid19/covid19-transmission.may30_2020.nextstrain.png" style="margin-bottom: 5px !important"> @@ -165,30 +167,36 @@ style="margin-bottom: 5px !important"> </a> <div style="text-align: right; line-height: 1"> <font SIZE=-1><em>Example UShER results displayed using <a href="https://nextstrain.org/" target=_blank>Nextstrain</a>. Sequences representing a hypothetical outbreak are yellow; previously sampled sequences are blue. Branches are labeled by nucleotide mutations.</em><BR> </font> </div> </div> </div> <h2 id="news">News</h2> <ul> +<li><b>May 11, 2021</b>: +Release of SARS-Cov-2 +<a href="/cgi-bin/hgTrackUi?db=wuhCor1&c=NC_045512v2&g=vaccines" target="_blank"> +Vaccines</a> track, displaying the alignment of three different mRNA vaccine sequences to the +coronavirus genome: the BioNTech/Pfizer BNT-162b2 sequence, the reconstructed BioNTech/Pfizer +BNT-162b2 RNA sequence, and the Moderna mRNA-1273 sequence. <li><b>February 17, 2021</b>: Release of SARS-Cov-2 <a href="/cgi-bin/hgTrackUi?db=wuhCor1&g=variantMuts" target="_blank"> Variants of Concern</a> track, displaying amino acid and nucelotide mutations in three "Variants of Concern" (B.1.1.7, B.1.351, and P.1) and one "Variant of Interest" (B.1.429, first identified in California), as defined in late January 2021. <li><b>January 29, 2021</b>: <a target="_blank" href="goldenPath/newsarch.html#012921"> January 29th SARS-CoV-2 update</a> - This update includes new data on sequence variants and phylogeny, spike protein amino-acid mutations, and antibody escape.</li> <li><b>January 8, 2021</b>: <a target="_blank" href="goldenPath/newsarch.html#010821"> January 8th SARS-CoV-2 update</a> - This update includes an updated track as well as three new tracks for the <a href="/cgi-bin/hgTracks?db=wuhCor1" target="_blank">coronavirus genome browser</a>, and a track for the <a