0017a306a24829adbd860a5deb7e9d4ece131df9 gperez2 Tue Jun 1 09:56:54 2021 -0700 Updating news for GenArk and Dynamic BLAT, refs #27556 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index 863f305..9d6c262 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -39,30 +39,130 @@
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Jun. 1, 2021    Genome Archive (GenArk) hubs and Dynamic BLAT

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+Do you have a favorite species or a research organism for which you'd like to visualize +the genomic sequence? With the recent addition of genomic assemblies for more than 1,300 +species, it's possible that your favorite is now available in the UCSC Genome Browser. +Check this list of new assemblies +to see if yours is a click away. Each of these Genome Browser assembly hubs comes pre-loaded +with several annotation tracks, gene models, and the ability to align genomic sequence to +the reference assembly using the BLAT +alignment tool. You can add your own data to your view of the assembly hub by uploading a +custom track +or creating a track hub.

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+We call this group of assembly hubs, the +Genome Archive (GenArk). The genomes in the GenArk are sourced from +NCBI RefSeq, +the Vertebrate Genomes Project (VGP) +and other projects. See the complete list of assembly hubs here.

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+GenArk assemblies can be found by searching the common name (e.g. + American Beaver) or GCA/GCF accession +(e.g. GCF_001984765.1) directly on the +Genome Browser Gateway page. +A full list can also be seen on the GenArk portal which +is organized by phylogenetic groups and projects:
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PrimatesAssembly statisticsTrack statistics
MammalsAssembly statisticsTrack statistics
BirdsAssembly statisticsTrack statistics
FishesAssembly statisticsTrack statistics
VertebratesAssembly statisticsTrack statistics
InvertebratesAssembly statisticsTrack statistics
FungiAssembly statisticsTrack statistics
PlantsAssembly statisticsTrack statistics
VGPAssembly statisticsTrack statistics
LegacyAssembly statisticsTrack statistics
Global Reference
Mouse Strains

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+The number of NCBI RefSeq assemblies has been increasing each year, and we expect the trend to continue as assemblies +from VGP, and other projects are released. Our next step is to add additional clades to GenArk including archaea, +viruses, and bacteria.

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+As mentioned above, assembly hubs in the GenArk allow for sequence alignment using the BLAT tool. We extended our traditional +BLAT tool to accommodate these assembly hubs and we call it +Dynamic BLAT. Dynamic BLAT +pre-computes index genomes files, which allows assemblies to have a BLAT server without needing it to be resident in the +computer's memory. Dynamic BLAT allows us to offer BLAT services on nearly all of our GenArk assemblies, with a few exceptions +due to excessive genome size.

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+We would like to thank NCBI RefSeq and Vertebrate Genome Project (VGP) for making these assemblies available. We would also +like to thank Hiram Clawson, Mark Diekhans, Galt Barber, Lou Nassar, and Gerardo Perez, and the rest of the Browser team +for their work on building the assembly hubs, creating GenArk, and extending BLAT to include these new assembly hubs.

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May. 11, 2021    Vaccines track available for the SARS-CoV-2 Genome Browser

We are happy to announce the release of the Vaccines track for the UCSC SARS-CoV-2 Genome Browser. This track shows the alignment of three different mRNA vaccine sequences to the coronavirus genome:

  1. The BioNTech/Pfizer BNT-162b2 sequence as published by the World Health Organization (WHO)
  2. The reconstructed BioNTech/Pfizer BNT-162b2 RNA as sequenced by the Andrew Fire lab, Stanford University School of Medicine