+We are pleased to announce the Genome +Aggregation Database (gnomAD) Constraint Metrics track, previously only on hg19, +is now also available on the human GRCh38/hg38 genome assembly.
++These data show various metrics of pathogenicity per-gene as predicted for gnomAD v2.1.1 and +identifies genes subject to strong selection against various classes of mutation. It is comprised +of four subtracks:
++More information on this track can be found in the track description page, as well as the +gnomAD site. We would like to thank the +Genome Aggregation Database Consortium for making these data available. We would also like to thank Lou +Nassar, Maximilian Haeussler, Anna Benet-Pages, and Gerardo Perez for their work in creating and releasing these +tracks.
+We are happy to announce an update to the GTEx cis-eQTL track for the human assembly (GRCh38/hg38). The track shows genetic variants likely affecting proximal gene expression in 49 human tissues from the Genotype-Tissue Expression (GTEx) V8 data release. With this update, we are introducing the DAP-G 95% credible set alongside the CAVIAR high-confidence set.
Hovering over items in the track display will show the variant ID (often a dbSNP rsID), the target gene, tissue, and posterior probablity (Causal Posterior Probability (CPP) for CAVIAR; SNP Posterior Inclusion Probability (PIP) for DAP-G). Clicking an item will show the details of that interaction