bb81d6d10b9c22486ee6745375383d9a8d136230 max Fri Aug 19 03:10:28 2022 -0700 documenting refseqgene alias for lrg, very confusing, refs #29891 diff --git src/hg/makeDb/trackDb/human/lrg.html src/hg/makeDb/trackDb/human/lrg.html index 93ce4db..cdb5d11 100644 --- src/hg/makeDb/trackDb/human/lrg.html +++ src/hg/makeDb/trackDb/human/lrg.html @@ -1,27 +1,35 @@ <H2>Description</H2> <P> <A HREF="http://www.lrg-sequence.org/" TARGET=_BLANK>Locus Reference Genomic (LRG)</A> sequences are manually curated, stable DNA sequences that surround a locus (typically a gene) and provide an unchanging coordinate system for reporting sequence variants. They are not necessarily identical to the corresponding sequence in a particular reference genome assembly (such as $date), but can be mapped to each version of a reference genome assembly in order to convert between the stable LRG variant coordinates and the various assembly coordinates. </P> + +<P> +We import the data from the LRG database at the EBI. +The NCBI RefSeqGene database is almost identical to LRG, +but it may contain a few more sequences. See <a target=_blank +href="https://www.ncbi.nlm.nih.gov/refseq/rsg/lrg/">the NCBI documentation</a>. +</P> + <P> Each LRG record also includes at least one stable transcript on which variants may be reported. These transcripts appear in the LRG Transcripts track in the Gene and Gene Predictions track section.</P> <H2>Methods</H2> <P> LRG sequences are suggested by the community studying a locus (for example, Locus-Specific Database curators, research laboratories, mutation consortia). LRG curators then examine the submitted transcript as well as other known transcripts at the locus, in the context of alignment and public expression data. For more information on the selection and annotation process, see the <A HREF="http://www.lrg-sequence.org/faq/" TARGET=_BLANK>LRG FAQ</A>,