bb81d6d10b9c22486ee6745375383d9a8d136230 max Fri Aug 19 03:10:28 2022 -0700 documenting refseqgene alias for lrg, very confusing, refs #29891 diff --git src/hg/makeDb/trackDb/human/lrgTranscriptAli.html src/hg/makeDb/trackDb/human/lrgTranscriptAli.html index 1521f67..56c96c7 100644 --- src/hg/makeDb/trackDb/human/lrgTranscriptAli.html +++ src/hg/makeDb/trackDb/human/lrgTranscriptAli.html @@ -1,30 +1,37 @@

Description

This track shows the fixed (unchanging) transcript(s) associated with each Locus Reference Genomic (LRG) sequence. LRG sequences are manually curated, stable DNA sequences that surround a locus (typically a gene) and provide an unchanging coordinate system for reporting sequence variants. They are not necessarily identical to the corresponding sequence in a particular reference genome assembly (such as $date), but can be mapped to each version of a reference genome assembly in order to convert between the stable LRG variant coordinates and the various assembly coordinates. +

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+We import the data from the LRG database at the EBI. +The NCBI RefSeqGene database is almost identical to LRG, +but it may contain a few more sequences. See the NCBI documentation.

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The LRG Regions track, in the Mapping and Sequencing Tracks section, includes more information about the LRG including the HGNC gene symbol for the gene at that locus, source of the LRG sequence, and summary of differences between LRG sequence and the genome assembly.

Methods

LRG sequences are suggested by the community studying a locus (for example, Locus-Specific Database curators, research laboratories, mutation consortia). LRG curators then examine the submitted transcript as well as other known transcripts at the locus, in the context of alignment and public expression data. For more information on the selection and annotation process, see the