48578d7724625cda2499bd11f8b6ce19463a1279 braney Fri Sep 2 15:24:25 2022 -0700 HGNC track is ready for QA. diff --git src/hg/makeDb/trackDb/human/hgnc.html src/hg/makeDb/trackDb/human/hgnc.html new file mode 100644 index 0000000..a90d2d1 --- /dev/null +++ src/hg/makeDb/trackDb/human/hgnc.html @@ -0,0 +1,36 @@ +<h2>Description</h2> +<p> +The <a href="https://www.genenames.org/tools/search" target="_blank">HGNC</a> is responsible for approving unique symbols and names for human loci, including protein coding genes, ncRNA genes and pseudogenes, to allow unambiguous scientific communication. +<p> +For each known human gene the HGNC approves a gene name and symbol (short-form abbreviation). All approved symbols are stored in the HGNC database, www.genenames.org, a curated online repository of HGNC-approved gene nomenclature, gene groups and associated resources including links to genomic, proteomic and phenotypic information. Each symbol is unique and we ensure that each gene is only given one approved gene symbol. It is necessary to provide a unique symbol for each gene so that we and others can talk about them, and this also facilitates electronic data retrieval from publications and databases. In preference each symbol maintains parallel construction in different members of a gene family and can also be used in other species, especially other vertebrates including mouse. + +<h2>Data Access</h2> +<p> +The raw data can be explored interactively with the <a href="../cgi-bin/hgTables" +target="_blank">Table Browser</a>, or the <a href="../cgi-bin/hgIntegrator" +target="_blank">Data Integrator</a>. For computational analysis, genome annotations are stored in +a bigBigFile file that can be downloaded from the +<a href="http://hgdownload.soe.ucsc.edu/gbdb/$db/hgnc/hgnc.bb" target="_blank">download +server</a>. Regional or genome-wide annotations can be converted from binary data to human readable +text using our command line utility <em>bigBedToBed</em> which can be compiled from source code or +downloaded as a precompiled binary for your system. Files and instructions can be found in the +<a href="http://hgdownload.soe.ucsc.edu/admin/exe/" target="_blank">utilities directory</a>. + +The utility can be used to obtain features within a given range, for example:</p> +<code>bigBedToBed -chrom=chr6 -start=0 -end=1000000 http://hgdownload.soe.ucsc.edu/gbdb/hg38/hgnc/hgnc.bb stdout</code> + +<p> + +<p> +Please refer to our <a href="../FAQ/FAQdownloads.html#download36" target="_blank">Data Access FAQ</a> +for more information or our <a href="https://groups.google.com/a/soe.ucsc.edu/forum/#!forum/genome" +target="_blank">mailing list</a> for archived user questions.</p> + +<h2>Credits</h2> +<p> +HGNC Database, HUGO Gene Nomenclature Committee (HGNC), European Molecular Biology Laboratory, European Bioinformatics Institute (EMBL-EBI), Wellcome Genome Campus, Hinxton, Cambridge CB10 1SD, United Kingdom <a href="/">www.genenames.org</a>. + +<h2>References</h2> +<p> +Tweedie S, Braschi B, Gray KA, Jones TEM, Seal RL, Yates B, Bruford EA. <strong>Genenames.org: the HGNC and VGNC resources in 2021.</strong> Nucleic Acids Res. PMID: <a href="https://www.ncbi.nlm.nih.gov/pubmed/33152070">33152070</a> PMCID: <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7779007/">PMC7779007</a> DOI: <a href="https://dx.doi.org/10.1093%2Fnar%2Fgkaa980">10.1093/nar/gkaa980</a> +</p>