d8a34f168b65a616fb185dbff94af89c426668b6 angie Mon Jul 10 12:02:02 2023 -0700 Mask position 337 in BN.1.2.3 -- noisy. diff --git src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml index a7bd6b6..f79de9b 100644 --- src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml +++ src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml @@ -75,30 +75,36 @@ BA.2.75: # Inherits BA.2 masking but has so many problems with false reversions I'm adding a ton here. representative: India/WB-INSACOG-1931503209307/2022 reversions: [ # BA.2-level but not masked BA.2-wide to avoid messing up recombinants: G670T, T2790C, T3037C, T4321C, G9424A, T9534C, T9866C, T10029C, T10198C, G18163A, T19955C, G20055A, T21618C, G22200T, A22578G, T22674C, C22679T, T22686C, G22688A, A22775G, T22813G, A22992G, A22995C, C23013A, G23055A, T23063A, C23075T, G23403A, T23525C, G23599T, A23604C, T23948G, T24424A, A24469T, T25000C, T26270C, G26577C, T27807C, T28271A, C29510A, # BA.2.75-defining, very dropout-prone: T4586C, G22001A, C22016T, A22033C, G22190A, C22577G, G26275A, # BA.2.75-defining, bad but maybe not quite as bad: T3796C, T3927C, T5183C, G12444A, A15451G, G22190A, A22331G, A22898G, G22942T, C23013A ] +BN.1.2.3: + # Inherits from BA.2.75 + representative: England/QEUH-326228D4/2022 + sites: [ 337 # https://github.com/cov-lineages/pango-designation/issues/2016#issuecomment-1626159006 + ] + BA.4: # BA.4 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: SouthAfrica/NICD-N41664/2022 ranges: [ [ 686, 694 ], [ 21765, 21770 ] ] BA.5: # BA.5 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: England/PHEP-YYFJPAM/2022 ranges: [ [ 21765, 21770 ] ] # Some of these should be reverted in recombinants, but we're pretty much past the point of # simultaneous Delta/Omicron and the noise from false reversions is so intolerable that we'll # just have to watch out for missing reversions when working with recombinants. reversions: [ G670T, T2790C, T3037C, A4184G, T4321C, G9424A, T9534C, T10198C, A12160G, T15714C, T17410C, G18163A, T19955C, G20055A, T21618C, G22200T, A22578G, T22674C, C22679T, T22686C, G22688A, A22775G, T22813G, G22882T, G22917T,