fe83e4d06fbda0328582179c72c789b1552cea52 angie Fri Feb 23 15:25:04 2024 -0800 More requested masked sites/ranges/reversions for BA.2.86. diff --git src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml index af269da..c31b082 100644 --- src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml +++ src/hg/utils/otto/sarscov2phylo/branchSpecificMask.yml @@ -97,34 +97,38 @@ BN.1.2.3: # Inherits from BA.2.75 representative: England/QEUH-326228D4/2022 sites: [ 337 # https://github.com/cov-lineages/pango-designation/issues/2016#issuecomment-1626159006 ] BA.2.86: # Inherits from BA.2 # @Over-There-Is requested 21610 - very messy indeed. # https://github.com/sars-cov-2-variants/lineage-proposals/issues/606#issuecomment-1801095482 # @aviczhl2 pointed out some recurring reversions: # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1072 representative: OY747147.1 ranges: [ [ 21765, 21770 ], # https://github.com/sars-cov-2-variants/lineage-proposals/issues/606 - [ 21610, 21624 ] ] # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1347 - sites: [ 21302, 21304, 21305, # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1190 + [ 21610, 21624 ], # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1347 + [ 21625, 21631 ], # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1380 + [ 22194, 22196 ] ] # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1380 + sites: [ 58, 59, # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1089 + 13427, # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1313 + 21302, 21304, 21305, # https://github.com/sars-cov-2-variants/lineage-proposals/issues/1190 ] - reversions: [ T21711C, C22032T, A22033C, G22034A, A23012G, G26610A ] + reversions: [ T21711C, C22032T, A22033C, G22034A, A22770G, A23012G, G26610A ] BA.4: # BA.4 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: SouthAfrica/NICD-N41664/2022 ranges: [ [ 686, 694 ], [ 21765, 21770 ] ] BA.5: # BA.5 is placed on the BA.2 branch so it inherits all the BA.2 sites. representative: England/PHEP-YYFJPAM/2022 ranges: [ [ 21765, 21770 ] ] # Some of these should be reverted in recombinants, but we're pretty much past the point of # simultaneous Delta/Omicron and the noise from false reversions is so intolerable that we'll # just have to watch out for missing reversions when working with recombinants. # False muts in recombinants that were later re-placed in BA.2.75: # XBD: G12160A, T22917G, T23018G