41e0c6eca3423830e7bb7601fc1a3d45c3deb72d gperez2 Tue Mar 26 12:32:58 2024 -0700 Fixing typos, refs #33084 #32916 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index d90f2d5..bbf2309 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -84,32 +84,32 @@ level for three different types of variation: missense, synonymous, and predicted loss of function.
  • Transcript Missense Constraint track: The missense constraint tracks are built similarly to the LoF constraint tracks, however the items displayed are based on missense Z scores. All items are colored black, and individual Z scores can be seen on mouseover.

    The GRCh37/hg19 Exome Variants v2.1.1 and the hg38/GRCh38 Genome Variants v3.1.1 tracks now have a non-cancer filter that allows the option to exclude/include variants from samples of individuals who were not ascertained for having cancer in a cancer study. These non-cancer subsets follow the new guidelines for clinical variant testing of BRCA1 and BRCA2 genes and are used for the assessment of breast cancer patients.

    We would like to thank the Genome Aggregation Database Consortium for making these data available. We would also like to thank -Chris Lee, Ana Benet-Pagès, Gerardo Perez, and Jairo Navarro for the creation and release of thee -tracks.

    +Chris Lee, Ana Benet-Pagès, Gerardo Perez, and Jairo Navarro for the creation and release of +these tracks.

    Mar. 07, 2024    New Prediction Scores super track and BayesDel track for hg19

    We are happy to announce the new Human Prediction Scores super track for the GRCh37/hg19 assembly. This super track currently includes the BayesDel track, which can be used for clinical variant classification research. BayesDel is a deleteriousness meta-score for coding and non-coding variants, single nucleotide variants, and small insertion/deletions. The range of the score is from -1.29334 to 0.75731. The higher the score, the more likely the variant is pathogenic. There are eight subtracks for the BayesDel track: four include pre-computed MaxAF-integrated BayesDel scores for missense variants, one for each base. The other four are of the same format, but scores are not MaxAF-integrated.