41e0c6eca3423830e7bb7601fc1a3d45c3deb72d gperez2 Tue Mar 26 12:32:58 2024 -0700 Fixing typos, refs #33084 #32916 diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index d90f2d5..bbf2309 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -84,32 +84,32 @@ level for three different types of variation: missense, synonymous, and predicted loss of function.</li> <li><b>Transcript Missense Constraint track</b>: The missense constraint tracks are built similarly to the LoF constraint tracks, however the items displayed are based on missense Z scores. All items are colored black, and individual Z scores can be seen on mouseover. </ol> <p> The GRCh37/hg19 Exome Variants v2.1.1 and the hg38/GRCh38 Genome Variants v3.1.1 tracks now have a non-cancer filter that allows the option to exclude/include variants from samples of individuals who were not ascertained for having cancer in a cancer study. These non-cancer subsets follow the new guidelines for clinical variant testing of BRCA1 and BRCA2 genes and are used for the assessment of breast cancer patients.</p> <p> We would like to thank the <a href="https://gnomad.broadinstitute.org/about" target="_blank">Genome Aggregation Database Consortium</a> for making these data available. We would also like to thank -Chris Lee, Ana Benet-Pagès, Gerardo Perez, and Jairo Navarro for the creation and release of thee -tracks.</p> +Chris Lee, Ana Benet-Pagès, Gerardo Perez, and Jairo Navarro for the creation and release of +these tracks.</p> <a name="030724"></a> <h2>Mar. 07, 2024 New Prediction Scores super track and BayesDel track for hg19</h2> <p> We are happy to announce the new Human Prediction Scores super track for the <a href="/cgi-bin/hgTrackUi?db=hg19&g=predictionScoresSuper">GRCh37/hg19</a> assembly. This super track currently includes the <a href="/cgi-bin/hgTrackUi?db=hg19&g=bayesDel">BayesDel track</a>, which can be used for clinical variant classification research. <a href="https://fenglab.chpc.utah.edu/BayesDel/BayesDel.html" target="_blank">BayesDel</a> is a deleteriousness meta-score for coding and non-coding variants, single nucleotide variants, and small insertion/deletions. The range of the score is from -1.29334 to 0.75731. The higher the score, the more likely the variant is pathogenic. There are eight subtracks for the BayesDel track: four include pre-computed MaxAF-integrated BayesDel scores for missense variants, one for each base. The other four are of the same format, but scores are not MaxAF-integrated.</p> <p>