402499d2b0c1740a020abe56fd818e36da17df20
jnavarr5
  Mon Aug 12 16:00:31 2024 -0700
Announcing the SpliceAI tracks for hg38 and hg19, refs #27141

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 <p>You can sign-up to get these announcements via our 
 <a target=_blank href="https://groups.google.com/a/soe.ucsc.edu/g/genome-announce?hl=en">Genome-announce</a>
 email list. We send around one short announcement email every two weeks.</p>
 
 <p>Smaller software changes are not announced here.  A summary of the three-weekly release changes can be 
 found <a target=_blank href="https://genecats.gi.ucsc.edu/builds/versions.html">here</a>. 
 For the full list of our daily code changes head to our <a
 href="https://github.com/ucscGenomeBrowser/kent/commits/master"
 target=_blank>GitHub page</a>. Lastly, see our <a href="credits.html" target="_blank">
 credits page</a> for acknowledgments of the data we host.</p>
 
 <!-- ============= 2024 archived news ============= -->
 <a name="2024"></a>
 
+<a name="081224"></a>
+<h2>Aug. 12, 2024 &nbsp;&nbsp; Illumina SpliceAI tracks for human (hg38 and hg19)</h2>
+<p>
+We pleased to announce the release of the <b>Illumina SpliceAI</b> tracks for the
+<a href="/cgi-bin/hgTrackUi?db=hg38&position=default&g=spliceAI" target="_blank">hg38</a> and
+<a href="/cgi-bin/hgTrackUi?db=hg19&position=default&g=spliceAI" target="_blank">hg19</a>
+human assemblies. SpliceAI is an
+<a href="https://github.com/Illumina/SpliceAI" target="_blank">open-source</a> deep
+learning splicing prediction algorithm that can predict splicing alterations caused by DNA
+variations. Such variants may activate nearby cryptic splice sites, leading to abnormal transcript
+isoforms. SpliceAI was developed at Illumina; a <a href="https://spliceailookup.broadinstitute.org"
+target="_blank">lookup tool</a> is provided by the Broad institute.</p>
+<p>
+<b>Important</b>: The SpliceAI data on the UCSC Genome Browser is directly from
+Illumina. However, since SpliceAI refers to the algorithm, and not the
+computed dataset, the data on the Broad server or other sources may have some differences between
+them. The SpliceAI scores are made available by Illumina only for academic or not-for-profit
+research only. By accessing the SpliceAI data, you acknowledge and agree that you may only use this
+data for your own personal academic or not-for-profit research only, and not for any other purposes.
+You may not use this data for any for-profit, clinical, or other commercial purpose without
+obtaining a commercial license from Illumina, Inc.
+</p>
+<p>
+We would like to thank Illumina for making this data available on the UCSC Genome Browser. We would
+also like to thank Luis Nassar and Jairo Navarro for the creation and release of the tracks.
+</p>
+
 <a name="073124"></a>
 <h2>Jul. 31, 2024 &nbsp;&nbsp; GENCODE &quot;KnownGene&quot; v45lift37 release for human (hg19)</h2>
 <p>
 We are excited to announce the release of the
 <a href="/cgi-bin/hgTrackUi?db=hg19&position=default&g=knownGene" target="_blank">GENCODE
 &quot;KnownGene&quot; v45lift37</a> gene track for hg19. With this release, the previous 2013 UCSC
 Genes track will be frozen and made available in the
 <a href="/cgi-bin/hgTrackUi?db=hg19&position=default&g=knownGeneArchive"
 target="_blank">GENCODE/UCSC Genes Archive</a> superTrack for reproducibility.
 As new GENCODE tracks are made available, previous versions will also be available in the archive.
 Beginning with this update, the &quot;KnownGene&quot; track will use GENCODE v45 gene models
 lifted to hg19, which replaces the old UCSC transcript IDs with the official GENCODE IDs.
 </p>
 <p>
 The following is an example of some GENCODE IDs that will replace the UCSC IDs in the update: