NOTE:
+ While the DECIPHER database is
+ open to the public, users seeking information about a personal medical or
+ genetic condition are urged to consult with a qualified physician for
+ diagnosis and for answers to personal questions.
+
Because the UCSC Genes mappings for CNVs are based on associations from + RefSeq and UniProt, they are dependent on any interpretations from those + sources. Furthermore, because many DECIPHER records refer to multiple gene + names, or syndromes not tightly mapped to individual genes, the associations + in this track should be treated with skepticism and any conclusions + based on them should be carefully scrutinized using independent + resources. +
+Data Display Agreement Notice
+ These data are only available for display in the Browser, and not for bulk
+ download. Access to bulk data may be obtained directly from DECIPHER
+ (https://www.deciphergenomics.org/about/data-sharing) and is subject to a
+ Data Access Agreement, in which the user certifies that no attempt to
+ identify individual patients will be undertaken. The same restrictions
+ apply to the public data displayed at UCSC in the UCSC Genome Browser;
+ no one is authorized to attempt to identify patients by any means.
+
These data are made available as soon as possible and may be a + pre-publication release. For information on the proper use of DECIPHER + data, please see https://www.deciphergenomics.org/about/data-sharing. +
+The DECIPHER consortium provides these data in good faith as a research + tool, but without verifying the accuracy, clinical validity, or utility of + the data. The DECIPHER consortium makes no warranty, express or implied, + nor assumes any legal liability or responsibility for any purpose for + which the data are used. +
++The +DECIPHER +database of submicroscopic chromosomal imbalance +collects clinical information about chromosomal +microdeletions/duplications/insertions, translocations and inversions, +and displays this information on the human genome map. +
+These tracks show genomic regions of reported cases and their +associated phenotype information. All data have passed the strict +consent requirements of the DECIPHER project and are approved for +unrestricted public release. Clicking the Patient View ID link +brings up a more detailed informational page on the patient at the +DECIPHER web site. + +
+The genomic locations of DECIPHER variants are labeled with the DECIPHER variant descriptions. +Mouseover on items shows variant details, clinical interpretation, and associated conditions. +Further information on each variant is displayed on the details page by a click onto any variant. +
+ ++For the CNVs track, the entries are colored by the type of variant: +
+A light-to-dark color gradient indicates the clinical significance of each variant, with +the lightest shade being benign, to the darkest shade being pathogenic. Detailed information on the +CNV color code is described here. +Items can be filtered according to the size of the variant, variant type, and clinical significance +using the track Configure options. +
+ ++For the SNVs track, the entries are colored according to the estimated clinical significance +of the variant: +
+Data provided by the DECIPHER project group are imported and processed +to create a simple BED track to annotate the genomic regions associated +with individual patients. +
+ + ++For more information on DECIPHER, please contact + +contact@deciphergenomics. +org +
+ ++Firth HV, Richards SM, Bevan AP, Clayton S, Corpas M, Rajan D, Van Vooren S, Moreau Y, Pettett RM, +Carter NP. + +DECIPHER: Database of Chromosomal Imbalance and Phenotype in Humans Using Ensembl Resources. +Am J Hum Genet. 2009 Apr;84(4):524-33. +PMID: 19344873; PMC: PMC2667985 +