7a7f7a92a1f0b41c59cf266efddd36a5202b4324 gperez2 Fri Dec 20 15:57:50 2024 -0800 Adding a link to the description page on how NCBI calculates orthologs, refs #30262 diff --git src/hg/makeDb/trackDb/human/refSeqComposite.html src/hg/makeDb/trackDb/human/refSeqComposite.html index 95d6387..5d940ee 100644 --- src/hg/makeDb/trackDb/human/refSeqComposite.html +++ src/hg/makeDb/trackDb/human/refSeqComposite.html @@ -73,32 +73,35 @@ Gene Mutation Database. This track is only available on the human genomes hg19 and hg38. It is the most restricted RefSeq subset, targeting clinical diagnostics. </li> <li> <em>RefSeq Historical</em> – previous RefSeq transcript versions, including NM_ accessions and HGVS searches. This track is only available on hg38. </li> <li> <em>NCBI Orthologs</em> – Orthologous genes were identified by <a target="_blank" href="https://www.ncbi.nlm.nih.gov/refseq/annotation_euk/process/"> NCBI's Eukaryotic Genome Annotation Pipeline</a> for the NCBI Gene dataset using a combination of protein sequence similarity and local synteny analysis. Orthology is determined between the genome being annotated and a reference genome, such as human or zebrafish, and pairs of orthologs are grouped together. Transitive relationships are inferred within each group, for example, zebrafish <-> - human <-> mouse. This track is available for the following assemblies: hg38, mm39, - danRer11, canFam6, and bosTau9. + human <-> mouse. For more information on how NCBI calculates orthologs, see the details + provided + <a target="_blank" href="https://www.ncbi.nlm.nih.gov/kis/info/how-are-orthologs-calculated/"> + here</a>. This track is available for the following assemblies: hg38, mm39, danRer11, canFam6, + and bosTau9. </li> </ul> </dl> <p> The <em>RefSeq All</em>, <em>RefSeq Curated</em>, <em>RefSeq Predicted</em>, <em>RefSeq HGMD</em>, <em>RefSeq Select/MANE</em> and <em>UCSC RefSeq</em> tracks follow the display conventions for <a href="../goldenPath/help/hgTracksHelp.html#GeneDisplay" target="_blank">gene prediction tracks</a>. The color shading indicates the level of review the RefSeq record has undergone: predicted (light), provisional (medium), or reviewed (dark), as defined by <a target=_blank href="https://www.ncbi.nlm.nih.gov/books/NBK21091/table/ch18.T.refseq_status_codes/?report=objectonly">RefSeq</a>. </p> <p> <table> <thead>