34f7d6002403040f75eb892b9a67a436503a1a36
lrnassar
  Mon Jan 13 15:04:08 2025 -0800
Relating gnomAD constraints to the constraints metric superTrack, refs #29043

diff --git src/hg/makeDb/trackDb/relatedTracks.ra src/hg/makeDb/trackDb/relatedTracks.ra
index 24ef95e..d565092 100644
--- src/hg/makeDb/trackDb/relatedTracks.ra
+++ src/hg/makeDb/trackDb/relatedTracks.ra
@@ -1,28 +1,31 @@
-# A space delimited file of track relatedness, format:
+# A space delimited file of track relatedness. All entries must be reciprocal. Format:
 # ucscDb track trackLinkingTo reason
 
 # hg38:
 hg38 knownGene knownGeneArchive View previous versions of GENCODE Genes
 hg38 knownGeneArchive knownGene View the latest GENCODE Genes version
 
 hg38 miRnaAtlas nonCodingRNAs View associated precursor miRnas
 hg38 nonCodingRNAs miRnaAtlas View expression of cleaved miRnas
 
 hg38 caddSuper gnomad View associated variants
 hg38 gnomad caddSuper View CADD scores for this variant and region
 
+hg38 constraintSuper gnomadPLI Predicted constraint metrics from gnomAD
+hg38 gnomadPLI constraintSuper Container track of various constraint scores
+
 hg38 revel liftHg38 Revel is based on hg19 and lifted to hg38. liftOver "chain" alignment from hg19 to hg38
 hg38 liftHg38 revel Revel scores were lifted using UCSC liftOver chains from hg38
 
 hg38 revel caddSuper CADD, a similar deleteriousness score, and not used as an input by REVEL
 hg38 caddSuper revel REVEL, a similar deleteriousness score
 
 hg38 liftHg19 grcIncidentDb GRC Incident database, to explore reasons why the assembly was changed
 hg38 grcIncidentDb liftHg19 LiftOver for hg38, explores how incident regions aligned between human assemblies
 
 hg38 ReMap liftHg19 NCBI ReMap, even though it has the same name, is a liftOver-like hg19/hg38 alignment, and unrelated to the ReMap database
 hg38 liftHg19 ReMap ReMap, even though it has the same name, is a database of transcription factor binding sites, unrelated to NCBI ReMap
 
 hg38 ReMap jaspar JASPAR is a database of predicted TF binding sites, based on short DNA matches. Unlike ReMap, the data is purely computational.
 
 hg38 jaspar ReMap ReMap is a database of TF binding sites inferred from ChIP-Seq Data. Unlike JASPAR predictions, these sites are supported by functional assay
@@ -48,19 +51,22 @@
 hg19 fixSeqLiftOverPsl liftHg38 Investigate how patches affect the whole-genome alignment used for liftOver
 hg19 liftHg38 fixSeqLiftOverPsl Investigate how assembly patches affect the liftOver alignment
 
 hg19 liftHg38 hg38ContigDiff Hg38 Diff shows contigs that were changed from hg19 to hg38
 hg19 hg38ContigDiff liftHg38 Investigate how contig changes affect the liftOver alignments
 
 hg19 jaspar ReMap ReMap is a database of TF binding sites inferred from ChIP-Seq Data. Unlike JASPAR predictions, these sites are supported by functional assay
 hg19 ReMap jaspar JASPAR is a database of predicted TF binding sites, based on short DNA matches. Unlike ReMap, the data is purely computational.
 
 hg19 ReMap liftHg38 NCBI ReMap, even though it has the same name, is a liftOver-like hg19/hg38 alignment, and unrelated to the ReMap database
 hg19 liftHg38 ReMap ReMap, even though it has the same name, is a database of transcription factor binding sites, unrelated to NCBI ReMap
 
 hg19 refSeqComposite pseudoYale60 NCBI RefSeq Curated and RefSeq Other contains pseudogenes, but the Yale annotation should be more comprehensive for this transcript type
 hg19 pseudoYale60 refSeqComposite NCBI RefSeq Curated and RefSeq Other also contain some transcribed and untranscribed pseudogenes, respectively.
 
+hg19 constraintSuper gnomadPLI Predicted constraint metrics from gnomAD
+hg19 gnomadPLI constraintSuper Container track of various constraint scores
+
 # mm39:
 
 mm39 knownGene knownGeneArchive View previous versions of GENCODE Genes
 mm39 knownGeneArchive knownGene View the latest GENCODE Genes version