05d4d7daf863400e820ccc217118ffddc52cc86c
jnavarr5
  Fri Mar 14 16:18:00 2025 -0700
Announcing the denovo-db track for hg19, refs #28790

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 email list. We send around one short announcement email every two weeks.</p>
 
 <p>Smaller software changes are not announced here.  A summary of the three-weekly release changes can be 
 found <a target=_blank href="https://genecats.gi.ucsc.edu/builds/versions.html">here</a>. 
 For the full list of our daily code changes head to our <a
 href="https://github.com/ucscGenomeBrowser/kent/commits/master"
 target=_blank>GitHub page</a>. Lastly, see our <a href="credits.html" target="_blank">
 credits page</a> for acknowledgments of the data we host.</p>
 
 <!-- ============= 2025 archived news ============= -->
 <a name="2025"></a>
 
+<a name="031425"></a>
+<h2>Mar. 14, 2025 &nbsp;&nbsp; denovo-db tracks for hg19 now available</h2>
+<p>
+We are excited to announce the release of two
+<a href="/cgi-bin/hgTrackUi?db=hg19&c=chr7&g=denovoDbComposite" target="_blank">denovo-db V.1.6.1</a>
+tracks for the hg19/GRCh37 genome assembly. The
+<a href="https://denovo-db.gs.washington.edu/denovo-db/index.jsp" target="_blank">denovo-db
+(version 1.6.1)</a> is a curated database of germline de novo variants in the human genome, defined
+as variants present in children but absent in their parents. With advancements in whole-exome and
+whole-genome sequencing, denovo-db consolidates data from extensive genetic studies, including those
+on neurodevelopmental disorders, but is not restricted to specific phenotypes. This database
+provides essential resources for researchers investigating variant characteristics, mutability, and
+associated phenotypes.</p>
+<p>
+The denovo-db V.1.6.1 composite track contains <a href="https://www.sfari.org/resource/simons-simplex-collection/"
+target="_blank">Simons Simplex Collection (SSC)</a> samples and non-ssc samples. The use of Simons
+Simplex Collection (SSC) is limited to projects related to advancing the field of autism and related
+developmental disorder research. Questions on SSC consents should be directed to
+collections@sfari.org. If you have questions or comments about the denovo-db, please write to
+denovo-db@uw.edu.</p>
+<p>
+We would like to thank denovo-db and the Simons Simplex Collection for making this data available.
+We would also like to thank Megna Chalamala, Gerardo Perez, Ana Benet-Pag&#232;s, and Jairo
+Navarro for the creation and release of these tracks on the UCSC Genome Browser.</p>
+
+
 <a name="030625"></a>
 <h2>Mar. 06, 2025 &nbsp;&nbsp; New MITOMAP track for hg38 and hg19</h2>
 <p>
 We are pleased to announce the release of the MITOMAP track for the
 <a target="_blank" href="/cgi-bin/hgTrackUi?db=hg38&c=chrM&g=mitoMap">hg38/GRCh38</a>
 and <a target="_blank"
 href="/cgi-bin/hgTrackUi?db=hg19&c=chrMT&g=mitoMap">hg19/GRCh37</a> human assemblies.
 <a target="_blank" href="https://www.mitomap.org/foswiki/bin/view/MITOMAP/WebHome">MITOMAP</a>
 is a database of human mitochondrial DNA (mtDNA) information containing a compilation of mtDNA
 variation, allowing users to look up human mitochondrial gene loci, search public mitochondrial
 sequences, and browse or search for reported nucleotide variants in both the general population and
 clinical disease studies.
 </p>
 <p>
 This release includes two tracks within the MITOMAP composite track: