5068f9fb8a6f15e6f71834e20db77e65e85528cf mspeir Wed Jul 16 11:16:59 2025 -0700 slightly tweaking name so that bitly link continues to work diff --git src/hg/htdocs/goldenPath/newsarch.html src/hg/htdocs/goldenPath/newsarch.html index 6c52af82c06..390f976f4e6 100755 --- src/hg/htdocs/goldenPath/newsarch.html +++ src/hg/htdocs/goldenPath/newsarch.html @@ -52,31 +52,31 @@ <p>You can sign-up to get these announcements via our <a target=_blank href="https://groups.google.com/a/soe.ucsc.edu/g/genome-announce?hl=en">Genome-announce</a> email list. We send around one short announcement email every two weeks.</p> <p>Smaller software changes are not announced here. A summary of the three-weekly release changes can be found <a target=_blank href="https://genecats.gi.ucsc.edu/builds/versions.html">here</a>. For the full list of our daily code changes head to our <a href="https://github.com/ucscGenomeBrowser/kent/commits/master" target=_blank>GitHub page</a>. Lastly, see our <a href="credits.html" target="_blank"> credits page</a> for acknowledgments of the data we host.</p> <!-- ============= 2025 archived news ============= --> <a name="2025"></a> -<a name="071525b"></a> +<a name="071525"></a> <h2>July 15, 2025 New pathogenicity prediction scores for human: MutScore and M-CAP</h2> <p> We have two new pathogenicity prediction score tracks available in our <a href="/cgi-bin/hgTrackUi?db=hg19&position=default&g=predictionScoresSuper" target="_blank">Deleteriousness Predictions</a> super track.</p> <ul> <li><a href="/cgi-bin/hgTrackUi?db=hg19&position=default&g=mutScore" target="_blank">MutScore</a> (hg19/hg38) - MutScore is a pathogenicity predictor that integrates unsupervised features of single DNA variants with information derived from such clusters. The predictive model for MutScore was trained with a random forest approach on medically-relevant mutations and subsequently tested against various genomic databases for both hereditary conditions and cancer (ClinVar, HGMD, and DoCM) to achieve high performance.</li> <li><a href="/cgi-bin/hgTrackUi?db=hg19&position=default&g=mcap" target="_blank">M-CAP</a> (hg19) - M-CAP is a pathogenicity classifier for rare missense variants tuned to the high sensitivity required in the clinic. By combining previous