dd8d056c5e4d059305de5c9ab86441284efd845a brianlee Tue Jul 29 09:37:39 2025 -0700 Collapsing Yale Aim3 milestones [ADGC3_M_22 , ADGC3_N_23] for readability diff --git src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html index 2640b6dbc20..11553ec3756 100755 --- src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html +++ src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html @@ -1,16 +1,16 @@ - +\1;95;0c Mermaid Gantt Chart @@ -215,37 +215,37 @@ Submit data (L0, L1) Whole-brain structure and activity mapping (.LIF, .XLS), zebrafish, 5 NPD genes (ADNP - NRXN1) : crit, milestone, ADGC3_K_14, 2025-10-01, 0d Submit data (L0, L1) High-throughput quantitative behavioral profiling (.raw, .XLS), zebrafish, 20 NPD genes (AKAP11 - WAC) : crit, milestone, ADGC3_L_14, 2025-12-31, 0d Submit data (L0, L1) Whole-brain structure and activity mapping (.LIF, .XLS), zebrafish, 5 NPD genes (PPP2R5D - MBD5) : crit, milestone, ADGC3_M_14, 2026-03-31, 0d Submit L3/L4 data from 40 NPD gene manuscript : crit, milestone, ADGC3_K_15, 2025-10-01, 0d Submit data (L0, L1) High-throughput quantitative behavioral profiling (.raw, .XLS), zebrafish, 20 NPD genes (CASKIN1 - XPO7) : crit, milestone, ADGC3_N_15, 2027-04-01, 0d Submit data (L0, L1) Whole-brain RNA-seq, zebrafish, 10 NPD genes (CHD8 - SMARCC2) : crit, milestone, ADGC3_N_17, 2027-04-01, 0d section Aim 3 ONGOING - Optimize spatial transcriptomic and epigenomic analysis of larval zebrafish using DBiT-Seq : IIIv11, 2024-01-01,52w ONGOING - Submit 5 DBiT RNA-seq and 5 DBiT ATAC-seq profiles : crit, IIIv12, after IIIv11,13w Optimize spatial transcriptomic and epigenomic analysis of larval zebrafish using DBiT-Seq : III_v11_new1, 2025-04-01,26w Produce 5-10 DBiT RNA-seq profiles (fastq) and 5-10 DBiT ATAC-seq profiles (fastq). : III_v11_new2, after III_v11_new1,13w Submit another 5 DBiT RNA-seq and 5 DBiT ATAC-seq profiles : crit, IIIv13, after III_v11_new2,13w Submit data [10-20 DBiT RNA-seq profiles (fastq) and 10-20 DBiT ATAC-seq profiles (fastq)] : crit, IIIv13_new1, after IIIv13,52w Optimize multi-omic CRISPR screen of NPD genes in hiPSC-NPCs : IIIv14, 2024-04-01,78w - Produce 5-10 DBiT RNA-seq profiles (fastq) and 5-10 DBiT ATAC-seq profiles (fastq) : IIIv14_new1, after IIIv14,13w + Produce 5-10 DBiT RNA-seq profiles (fastq) and 5-10 DBiT ATAC-seq profiles : IIIv14_new1, after IIIv14,13w Submit data from multi-omic CRISPR screen of NPD genes in hiPSCs :crit, IIIv15, after IIIv14_new1,13w Submit data [10-20 DBiT RNA-seq profiles (fastq) and 10-20 DBiT ATAC-seq profiles (fastq)] : crit, IIIv16, after IIIv15,52w - ADGC3_M_22 Submit data (L0, L1) Transcriptomic and epigenomic analysis (5 DBiT RNA-seq profiles (fastq) and 5 DBiT ATAC-seq profiles (fastq)), zebrafish, one NPD gene (CHD8) : crit, milestone, ADGC3_M_22, 2026-03-31, 0d - ADGC3_N_22 Submit data (L0, L1) Transcriptomic and epigenomic analysis (10-20 DBiT RNA-seq profiles (fastq) and 10-20 DBiT ATAC-seq profiles (fastq)), zebrafish, two NPD genes (TBD, possibly SMARCC2, SHANK3) : crit, milestone, ADGC3_N_22, 2027-04-01, 0d - ADGC3_M_23 Submit data (L0, L1) CRISPRi organoid transcriptomic and epigenomic analysis (5-10 DBiT RNA-seq profiles (fastq) and 5-10 DBiT ATAC-seq profiles (fastq)), one NPD gene (CHD8) : crit, milestone, ADGC3_M_23, 2026-03-31, 0d - ADGC3_N_23 Submit data (L0, L1) CRISPRi organoid transcriptomic and epigenomic analysis (10-20 DBiT RNA-seq profiles (fastq) and 10-20 DBiT ATAC-seq profiles (fastq)), two NPD genes (TBD, possibly SMARCC2, SHANK3) : crit, milestone, ADGC3_N_23, 2027-04-01, 0d + Submit data (L0, L1) Transcriptomic and epigenomic analysis 5 DBiT RNA-seq, 5 DBiT ATAC-seq, zebrafish CHD8 : crit, milestone, ADGC3_M_22, 2026-03-31, 0d + Submit data (L0, L1) Transcriptomic and epigenomic analysis 10-20 DBiT RNA-seq and DBiT ATAC-seq profiles, zebrafish 2 TBD genes : crit, milestone, ADGC3_N_22, 2027-04-01, 0d + Submit data (L0, L1) CRISPRi organoid transcriptomic and epigenomic analysis 5-10 DBiT RNA-seq profiles and DBiT ATAC-seq profiles, CHD8 : crit, milestone, ADGC3_M_23, 2026-03-31, 0d + Submit data (L0, L1) CRISPRi organoid transcriptomic and epigenomic analysis 10-20 DBiT RNA-seq and DBiT ATAC-seq, two TBD genes : crit, milestone, ADGC3_N_23, 2027-04-01, 0d
ADGC4 Broad timeline
    
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         title       ADGC4  Broad