+ + Genome Browser screenshot of the DDG2P track with the mouseover tooltip on the BRCA1 gene. +
+You can sign-up to get these announcements via our Genome-announce email list. We send around one short announcement email every two weeks.
Smaller software changes are not announced here. A summary of the three-weekly release changes can be found here. For the full list of our daily code changes head to our GitHub page. Lastly, see our credits page for acknowledgments of the data we host.
+ ++We are pleased to announce the release of the Developmental Disorders Genotype-to-Phenotype (DDG2P) track for +hg19 and +hg38. The DDG2P +track displays genes associated with severe developmental disorders. The track can be used to +filter genomic sequencing data of people with genetic disorders to identify likely causative +variants and accelerate diagnosis. +
++Items in this track are colored according to the likelihood that the gene-disease +association is true:
+Each mouseover tooltip provides the following information:
+
+ + Genome Browser screenshot of the DDG2P track with the mouseover tooltip on the BRCA1 gene. +
++We would like to thank the G2P project for making this data publicly available. We would also like to thank +Jaidan Jenkins-Kiefer and Jairo Navarro Gonzalez for the creation and release of the Genome Browser +tracks.
We are excited to announce the release of the MaveDB Experiment Heatmaps and Alignment track for hg38. This release provides heatmaps of multiplexed assays of variant effects (MAVE) from MaveDB. Each heatmap presents the results of an experiment where many small substitutions were tested within a gene to examine their functional consequences. Accompanying tracks display alignments of each experiment sequence to the genome.
Please note that only a subset of MaveDB experiments could be displayed as heatmaps; the sequence alignments in this track only cover those experiments.