8d0f447512945c3836ddd109eabeae0ffb7b6add brianlee Thu Sep 11 11:43:15 2025 -0700 Aligning ADGC1 & ADGC2 to Start Grant Year2, displaying all timelines at same base graph diff --git src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html index 1d7a76bb54e..077637a9fa1 100755 --- src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html +++ src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html @@ -25,32 +25,30 @@
     gantt
     dateFormat  YYYY-MM-DD
     axisFormat  %Y-Q%q
     title       ADGC1  UCLA
 
 
     section Grant Year                                                                           
     Start Grant Year 2     :milestone, m1, 2024-03-31, 0d                                       
     Start Grant Year 3     :milestone, m1, 2025-03-31, 0d                                       
     Start Grant Year 4     :milestone, m1, 2026-03-31, 0d                                        
     Start Grant Year 5     :milestone, m1, 2027-04-01, 0d         
     
     section AIM 1 
-    Generate stable clonal iPSC lines for 10 gene mutations in KOLF2.2J (Capstone; BATCH A)     :  t1, 2024-01-01, 2024-07-01
-    Generate stable clonal iPSC lines for 10 gene mutations in CIRM line (Capstone; BATCH A)    : t2, 2024-01-01, 2024-07-01
     Generate stable clonal iPSC lines for additional 25 gene mutations in KOLF2.2J and CIRM (BATCH B)    :        t3, 2024-04-01, 2024-09-30
     QC of Capstone  lines to date pending    : t4, 2024-04-01, 39w
     Generate and QC stable clonal iPSC lines for additional 65 gene mutations in KOLF2.2J and CIRM   :    t6, after t3, 52w
     QC of all generated lines to date pending   :   t7, after t3, 78w
     Share 20 BATCHA gene edited iPSC lines (10 NPD genes x 2 iPSC backgrounds)   :  t8, after t4, 26w
     Share  180 BATCH B+C  gene edited iPSC lines (90 NPD genes x 2 iPSC backgrounds)  : t10,  after t8, 39w
     Troubleshoot and perform 2nd attempt of difficult KO genes :  t11, after t10, 13w
 
     section AIM 2
     Quantify proliferation rates of NPCs from 10 Capstone iPSC clonal lines  : t5, after t1, 26w       
     Quantify proliferation rates of NPCs from all  iPSC clonal lines from all batches    : t9, after t4, 52w
     Bulk RNA-seq profiles (4 replicates per gene  x (10 NPD iPSC lines + 2 controls) x 1 background (KOLF2.2J) iPSC background lines; fastq))  :  t20, after t2, 52w
     Submit data from first capstone experiment (KOLF2.2J background)  :crit, t22, after t20, 13w
     Bulk RNA-seq profiles ((4 replicates per gene  x (10 NPD iPSC lines + 2 controls) x 1 background (CIRM line) iPSC background lines; fastq)) :  t21, after t3, 39w
     Submit data from first capstone experiment (CIRM background) :crit, t23, after t21, 13w
@@ -107,31 +105,31 @@
   
    
         gantt
         dateFormat  YYYY-MM-DD
         axisFormat  %Y-Q%q
         title       ADGC2  MiNND
 
         section Grant Year
         Start Grant Year 2     :milestone, m1, 2024-03-31, 0d
         Start Grant Year 3     :milestone, m1, 2025-03-31, 0d
         Start Grant Year 4     :milestone, m1, 2026-03-31, 0d
         Start Grant Year 5     :milestone, m1, 2027-04-01, 0d
 
         section Aim 1
-        Generated 217 new lines including 10 NTC (total 332 lines). We generated iNs from 180 lines.  :done, IIt1, 2024-01-01, 2025-04-01
+        Generated 217 new lines including 10 NTC (total 332 lines). We generated iNs from 180 lines.  :done, IIt1, 2024-04-01, 2025-04-01
         Production of 72 iPSC lines on average per quarter (3 batches of 23 gene mutations + 1 NTC) :   IIt2, after IIt1,13w
         Production of 72 iPSC lines on average per quarter (3 batches of 23 gene mutations + 1 NTC) :   IIt3, after IIt2,13w
         Production of 72 iPSC lines on average per quarter (3 batches of 23 gene mutations + 1 NTC) :   IIt4, after IIt3,13w
         Production of 72 iPSC lines on average per quarter (3 batches of 23 gene mutations + 1 NTC) :   IIt5, after IIt4,13w
 
         section Aim 2
         Submitted scRNA-seq data for 157 lines to the DRACC. : done, IIt6, 2024-04-01,52w
         Submit scRNA-seq data for 72 edited lines (3×23 gene mutations + 1 NTC) from last quarter. :crit,   IIt7, after IIt6,13w
         Submit scRNA-seq data for 72 edited lines (3×23 mutations + 1 NTC) & L1-L3 datasets (fastq, RDS, Excel) from last year. :crit,   IIt8, after IIt7,13w
         Submit scRNA-seq data for 72 edited lines (3×23 mutations + 1 NTC) & L1-L3 datasets (fastq, RDS, Excel) from last quarter. :crit,   IIt9, after IIt8,13w
         Submit scRNA-seq data for 72 edited lines (3×23 mutations + 1 NTC) & L1-L3 datasets (fastq, RDS, Excel) from last quarter.  :crit,   IIt10, after IIt9,13w
         Submitted 113 lines morphometrics imaging data. :done, IIt11, 2024-04-01,52w
         Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 :crit,   IIt12, after IIt11,13w
         Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 :crit,   IIt13, after IIt12,13w
         Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 :crit,   IIt14, after IIt13,13w