1eb778792659124aa071876e2c5541bc8e3d6b3d
max
  Tue Nov 4 01:54:21 2025 -0800
adding a link to more updated ancient dna tracks, refs #36592

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+<html><head>

+<meta http-equiv="content-type" content="text/html; charset=UTF-8"></head>

+ <body>

+<p><span style="font-size: 12pt;"><strong>Description</strong> </span></p>

+<p>The NCBI <strong>AL</strong>lele <strong>F</strong>requency <strong>A</strong>ggregator (<a href="https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/">ALFA</a>)

+ pipeline is developed to compute allele frequency for variants in dbGaP

+ across approved un-restricted studies and to provide the data as 

+open-access to the public through dbSNP. The goal of the ALFA project is

+ to make frequency data from over 1M dbGaP subjects open-access in 

+future releases to facilitate discoveries and interpretations of common 

+and rare variants with biological impacts or causing diseases.</p>

+<p>The R4 release of 408,709 subjects included allele 

+counts and frequency for 15.5 million rs site including 959,966 ClinVar RS IDs. More information about ALFA can 

+be found at https://www.ncbi.nlm.nih.gov/snp/docs/gsr/alfa/ and any 

+questions about ALFA track data should be forwarded to 

+&lt;mailto:snp-admin@ncbi.nlm.nih.gov&gt;.</p>

+<p><span style="font-size: 12pt;"><strong>Subtracks</strong></span></p>

+<p>This track contains data from 12 populations:</p>

+<p>* ALFA data for African population</p>

+<p>* ALFA data for African American population</p>

+<p>* ALFA data for African Others population</p>

+<p>* ALFA data for Asian population</p>

+<p>* ALFA data for East Asian population</p>

+<p>* ALFA data for European population</p>

+<p>* ALFA data for Global population</p>

+<p>* ALFA data for Latin American 1 population</p>

+<p>* ALFA data for Latin American 2 population</p>

+<p>* ALFA data for Other population</p>

+<p>* ALFA data for Other Asian population</p>

+<p>* ALFA data for South Asian population</p>

+<h2>&nbsp;</h2>

+<h2>Display Conventions and Configuration</h2>

+<h3>Labels</h3>

+<p>The variant label is the dbSNP reference SNP ID (rsid).</p>

+<h3>Mouseover</h3>

+<p>The mouseover (displayed when the mouse is hovered over a variant) shows the following:</p>

+<ul>

+<li>Chromosome</li>

+<li>position</li>

+<li>Reference allele and frequency</li>

+<li>Alternate allele and frequency</li>

+</ul>

+<h3>&nbsp;</h3>

+<h3>Detail Page</h3>

+<p>The detail page contains the following:</p>

+<ul>

+<li><a>link to the dbSNP RS Page of the variation</a></li>

+<li><a>chromosome position</a></li>

+<li><a>mouseover label (allele frequencies)</a></li>

+<li><a>track hub date last updated</a></li>

+</ul>

+<p>&nbsp;&nbsp;</p>

+<h3>Variant Colors</h3>

+<p><a>The colors indicate the alternate allele frequencies</a><a>. </a></p>

+<ul>

+<li style="color: #ff0000;"><strong>red: alternate allele frequency falls in [0.5, 1]<br></strong></li>

+</ul>

+<ul>

+<li style="color: #0000ff;"><strong>blue: alternate allele frequency falls in [0.4, 0.5)<br></strong></li>

+</ul>

+<ul>

+<li style="color: #ee82ee;"><strong>violet: alternate allele frequency falls in [0.3, 0.4)<br></strong></li>

+</ul>

+<ul>

+<li style="color: #9c6597;"><strong>light violet: alternate allele frequency falls in [0.2, 0.3)<br></strong></li>

+</ul>

+<ul>

+<li style="color: #007fff;"><strong>light azure: alternate allele frequency falls in [0.1, 0.2)<br></strong></li>

+</ul>

+<ul>

+<li style="color: #a52a2a;"><strong>brown: alternate alelle frequency falls in [0, 0.1)<br></strong></li>

+</ul>

+ 

+

+</body></html>
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