e4b550095f70e0d9b828dccaa740f9a49ecc3e15 brianlee Mon Jan 26 14:27:52 2026 -0800 Cutting Grant Year 2 off milestone, revamping Broads to have Spreadsheet mapping ADGC4_Aim3_year4_item2 -> ADGC4_Aim3_year4_D_16 diff --git src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html index f5ab9dbb9ce..62bd0836599 100755 --- src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html +++ src/hg/cirm/gateway/htdocs/sspsygeneTimeline.html @@ -1,437 +1,430 @@ <!DOCTYPE html> <!--#set var="TITLE" value="CIRM CESCG People and Labs" --> <!--#include virtual="setRoot.html" --> <!--#include virtual="${ROOT}inc/header.html" --> <head> <meta charset="UTF-8"> <title>Mermaid Gantt Chart</title> <script src="https://cdn.jsdelivr.net/npm/mermaid/dist/mermaid.min.js"></script> <script> mermaid.initialize({ startOnLoad: true }); </script> </head> <div class="cirm-page-body"> <div class="cirm-page-title back-dark-pink"> <h5 class="cirm-page-title-text">SSPsyGene Milestone Charts</h5> </div> <a name="ADGC1"></a> <!-- Start of ADGC1 Henry Gantt Chart--> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC1 UCLA Chart</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC1 UCLA [RM1MH132651] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, year3_ucla, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d click year3_ucla href "https://docs.google.com/spreadsheets/d/1Ml_UXDHE4UZo2kjLp1aZLa0KxLtLSnVi/edit?gid=1138387919#gid=1138387919&range=J1:M20" section AIM 1 section AIM 2 Quantify proliferation rates/IF/morphology of IPSC/NPC/Neurons from Capstone Lines 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_I_8, 2025-03-31, 0d Quantify proliferation rates/IF/morphology of IPSC/NPC/Neurons from BATCH B 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_JK_8, 2025-09-30, 0d Quantify proliferation rates/IF/morphology of IPSC/NPC/Neurons from BATCH C 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_LM_8, 2026-03-31, 0d Quantify proliferation rates/IF/morphology of IPSC/NPC/Neurons from BATCH D 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_NO_8, 2026-10-01, 0d Quantify proliferation rates/IF/morphology of IPSC/NPC/Neurons from BATCH E 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_P_8, 2026-12-31, 0d Quantify proliferation rates/IF/morphology of IPSC/NPC/Neurons from BATCH F 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_Q_8, 2027-03-31, 0d Submit L0-L1 from BATCH B, producing bulk RNA-seq profiles 3 tech reps, 4 bio reps/gene × (20 NPD + 2 ctrl) × 2 (KOLF2.2J/CIRM) iPSC lines; .fastq : crit, milestone, ADGC1_LM_111213, 2026-03-31, 0d Submit L0-L1 from BATCH C, producing bulk RNA-seq profiles 3 tech reps, 4 bio reps/gene × (20 NPD + 2 ctrl) × 2 (KOLF2.2J/CIRM) iPSC lines; .fastq : crit, milestone, ADGC1_NO_111213, 2026-10-01, 0d Submit L0-L1 from BATCH D, producing bulk RNA-seq profiles 3 tech reps, 4 bio reps/gene × (20 NPD + 2 ctrl) × 2 (KOLF2.2J/CIRM) iPSC lines; .fastq : crit, milestone, ADGC1_P_111213, 2026-12-31, 0d Submit L0-L1 from BATCH E-G, producing bulk RNA-seq profiles 3 tech reps, 4 bio reps/gene × (20 NPD + 2 ctrl) × 2 (KOLF2.2J/CIRM) iPSC lines; .fastq : crit, milestone, ADGC1_Q_111213, 2027-03-31, 0d Complete villages - submit L0-L1 to DRACC : crit, milestone, ADGC1_JK_14, 2025-09-30, 0d Village Analysis - submit L0-L1 to DRACC : crit, milestone, ADGC1_LM_14, 2026-03-31, 0d Calcium Imaging Capstone Analysis 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_K_15, 2025-09-30, 0d Calcium Imaging analysis excitatory/inhibitory neurons - Capstone Analysis 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds : crit, milestone, ADGC1_M_15, 2026-03-31, 0d Calcium Imaging Experiments and analysis of future batches 10 genes, 22 iPSC lines (20 NPD + 2 ctrl) × 2 backgrounds (Submit L0-L4 to DRACC) : crit, milestone, ADGC1_NOPQ_15, 2027-03-31, 0d section AIM 3 Perform codex Capstone Lines (10 Genes, 20 NPD iPSC lines + 2 control lines) x 2 iPSC background lines; 4 well replicates/line; qptiff format) : crit, milestone, ADGC1_J_161718, 2025-07-01, 0d Spatial Proteomics Analysis Capstone Lines : crit, milestone, ADGC1_K_161718, 2025-09-30, 0d Perform codex BATCH B (10 Genes, 20 NPD iPSC lines + 2 control lines) x 2 iPSC background lines; 4 well replicates/line; qptiff format) : crit, milestone, ADGC1_L_161718, 2025-12-31, 0d Spatial Proteomics Analysis BATCH B : crit, milestone, ADGC1_M_161718, 2026-03-31, 0d Perform codex BATCH C (10 Genes, 20 NPD iPSC lines + 2 control lines) x 2 iPSC background lines; 4 well replicates/line; qptiff format) : crit, milestone, ADGC1_N_161718, 2027-03-31, 0d Spatial Proteomics Analysis BATCH C : crit, milestone, ADGC1_O_161718, 2027-03-31, 0d Perform codex and analysis for future batches : crit, milestone, ADGC1_Q_161718, 2027-03-31, 0d Organoid snRNAseq analysis for Capstone Genes : crit, milestone, ADGC1_J_1920, 2025-07-01, 0d Perform snRNAseq for BATCH B (10 Genes, 20 NPD iPSC lines + 2 control lines) x 2 iPSC background lines; 2-4 organoid replicates/line; tif format) : crit, milestone, ADGC1_K_1920, 2025-09-30, 0d Organoid snRNAseq analysis for BATCH B : crit, milestone, ADGC1_L_1920, 2025-12-31, 0d Perform snRNAseq for BATCH C (10 Genes, 20 NPD iPSC lines + 2 control lines) x 2 iPSC background lines; 2-4 organoid replicates/line; tif format) : crit, milestone, ADGC1_M_1920, 2026-03-31, 0d Organoid snRNAseq analysis C : crit, milestone, ADGC1_N_1920, 2027-03-31, 0d Perform Integrative analysis across first 30 genes and across experimental modalities (Spatial and snRNAseq). Submit L3-L4 level data by this time at the latest : crit, milestone, ADGC1_O_1920, 2027-03-31, 0d Perform snRNAseq for future batches : crit, milestone, ADGC1_P_1920, 2026-12-31, 0d Organoid snRNAseq Analysis for future batches : crit, milestone, ADGC1_Q_1920, 2027-03-31, 0d </pre> </div> </div> <a name="ADGC2"></a> <!-- Start of ADGC2 Henry Gantt Chart--> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC2 MiNND timeline</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC2 MiNND [RM1MH133065] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, year3_minnd, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d click year3_minnd href "https://docs.google.com/spreadsheets/d/1GNrJaIjs6nPlFY4j2AlZSlTDf2-mi17d/edit?gid=1137576441#gid=1137576441&range=J1:M34" section Aim 1 section Aim 2 Submit scRNA-seq data for 72 edited lines (3×23 gene mutations + 1 NTC) from last quarter. : crit, milestone, ADGC2_J_11, 2025-06-30, 0d Submit scRNA-seq data for 72 edited lines (3×23 mutations + 1 NTC) & L1-L3 datasets (fastq, RDS, Excel) from last year. : crit, milestone, ADGC2_K_11, 2025-09-30, 0d Submit scRNA-seq data for 72 edited lines (3×23 mutations + 1 NTC) & L1-L3 datasets (fastq, RDS, Excel) from last quarter : crit, milestone, ADGC2_L_11, 2025-12-31, 0d Submit scRNA-seq data for 72 edited lines (3×23 mutations + 1 NTC) & L1-L3 datasets (fastq, RDS, Excel) from last quarter : crit, milestone, ADGC2_M_11, 2026-03-31, 0d Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 : crit, milestone, ADGC2_J_12, 2025-06-30, 0d Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 : crit, milestone, ADGC2_K_12, 2025-09-30, 0d Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 : crit, milestone, ADGC2_L_12, 2025-12-31, 0d Submit Imaging of 72 iPSC lines (3×23 mutations + 1 NTC) & prior quarter L1-L3 : crit, milestone, ADGC2_M_12, 2026-03-31, 0d CODEX 3x data to BIL, generate LoF variants in 1-2 new lines : crit, milestone, ADGC2_M_13, 2026-03-31, 0d section Aim 3 Submit Synaptic Optical Imaging of 72 iPSC (3×23 mutations + 1 NTC) : crit, milestone, ADGC2_J_19, 2025-06-30, 0d Submit Synaptic Optical Imaging of 72 iPSC (3×23 mutations + 1 NTC) : crit, milestone, ADGC2_K_19, 2025-09-30, 0d Begin to upload L1-L3 analysis for data from previous year : crit, milestone, ADGC2_K_20, 2025-09-30, 0d Submit Synaptic Optical Imaging of 72 iPSC (3×23 mutations + 1 NTC) : crit, milestone, ADGC2_L_19, 2025-12-31, 0d Continue upload L1-L3 analysis for data from previous year : crit, milestone, ADGC2_L_20, 2025-12-31, 0d Submit Synaptic Optical Imaging of 72 iPSC (3×23 mutations + 1 NTC) : crit, milestone, ADGC2_M_19, 2026-03-31, 0d Continue upload L1-L3 analysis for data from previous year : crit, milestone, ADGC2_M_20, 2026-03-31, 0d section Aim4 Submit PatchSeq data for 192 NTC lines L0 data : crit, milestone, ADGC2_J_27, 2025-06-30, 0d Submit PatchSeq data for 192 NTC lines L0 data : crit, milestone, ADGC2_K_27, 2025-09-30, 0d Submit PatchSeq data for 192 NTC lines L0 data : crit, milestone, ADGC2_L_27, 2025-12-31, 0d Submit PatchSeq data for 192 NTC lines L0 data : crit, milestone, ADGC2_M_27, 2026-03-31, 0d Submit PatchSeq data for 192 cells L1-L3 : crit, milestone, ADGC2_K_28, 2025-09-30, 0d Submit PatchSeq data for 192 cells L1-L3 : crit, milestone, ADGC2_L_28, 2025-12-31, 0d Submit PatchSeq data for 192 cells L1-L3 : crit, milestone, ADGC2_M_28, 2026-03-31, 0d </pre> </div> </div> <a name="ADGC3"></a> <!-- Start of ADGC3 Henry Gantt Chart--> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC3 Yale timeline</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC3 Yale [RM1MH132648] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, year3_yale, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d click year3_yale href "https://docs.google.com/spreadsheets/d/10xWymZXsDlDQ9uwU5YPAKwyflUMzpDS4/edit?gid=1305684354#gid=1305684354&range=J1:M25" section Aim 1 Submit initial data (L0, L1) CRISPRi MEA and calcium imaging of 15 ASD genes in iGLUTs and/or iGABAs (ARID1B - SHANK3) : crit, milestone, ADGC3_N_5, 2027-03-31, 0d Submit initial data (L0, L1) CRISPRi ECCITEseq, KOLF2.2J and CW20107 in iGLUTs (fastq), 10 capstone genes (ARID1B - SMARCC2) : crit, milestone, ADGC3_K_6, 2025-09-30, 0d Submit initial data (L0, L1) CRISPRi organoid models ECCITEseq of 10 capstone genes (ARID1B - SMARCC2) genes in KOLF2.2J : crit, milestone, ADGC3_N_6, 2027-03-31, 0d Submit ECCITEseq data (L0, L1) to DRACC for 29 NDD genes (ANK3 - WAC) in induced NPCs, glutamatergic neurons, and GABAergic neurons; iGLUT 3182-3-clone5 (iNPC, d7 iGLUT and d21 iGLUT) and iGABA 553-3-clone34 (d36 iGABA) : done, milestone, ADGC3_I_7, 2025-03-31, 0d Submit L3/L4 data from iGLUT manuscript : crit, milestone, ADGC3_K_7, 2025-09-30, 0d section Aim 2 Submit data (L0, L1) High-throughput quantitative behavioral profiling (.raw, .XLS), zebrafish, 10 stable mutant lines (ADNP - SYNGAP1) : crit, milestone, ADGC3_I_12, 2025-03-31, 0d Submit data (L0, L1) High-throughput quantitative behavioral profiling (.raw, .XLS), zebrafish, 20 NPD genes (ANK2 - SMARCC2) : crit, milestone, ADGC3_J_14, 2025-07-01, 0d Submit data (L0, L1) Whole-brain structure and activity mapping (.LIF, .XLS), zebrafish, 5 NPD genes (ADNP - NRXN1) : crit, milestone, ADGC3_K_14, 2025-09-30, 0d Submit data (L0, L1) High-throughput quantitative behavioral profiling (.raw, .XLS), zebrafish, 20 NPD genes (AKAP11 - WAC) : crit, milestone, ADGC3_L_14, 2025-12-31, 0d Submit data (L0, L1) Whole-brain structure and activity mapping (.LIF, .XLS), zebrafish, 5 NPD genes (PPP2R5D - MBD5) : crit, milestone, ADGC3_M_14, 2026-03-31, 0d Submit L3/L4 data from 40 NPD gene manuscript : crit, milestone, ADGC3_K_15, 2025-09-30, 0d Submit data (L0, L1) High-throughput quantitative behavioral profiling (.raw, .XLS), zebrafish, 20 NPD genes (CASKIN1 - XPO7) : crit, milestone, ADGC3_N_15, 2027-03-31, 0d Submit data (L0, L1) Whole-brain RNA-seq, zebrafish, 10 NPD genes (CHD8 - SMARCC2) : crit, milestone, ADGC3_N_17, 2027-03-31, 0d section Aim 3 Submit data (L0, L1) Transcriptomic and epigenomic analysis 5 DBiT RNA-seq, 5 DBiT ATAC-seq, zebrafish CHD8 : crit, milestone, ADGC3_M_22, 2026-03-31, 0d Submit data (L0, L1) Transcriptomic and epigenomic analysis 10-20 DBiT RNA-seq and DBiT ATAC-seq profiles, zebrafish 2 TBD genes : crit, milestone, ADGC3_N_22, 2027-03-31, 0d Submit data (L0, L1) CRISPRi organoid transcriptomic and epigenomic analysis 5-10 DBiT RNA-seq profiles and DBiT ATAC-seq profiles, CHD8 : crit, milestone, ADGC3_M_23, 2026-03-31, 0d Submit data (L0, L1) CRISPRi organoid transcriptomic and epigenomic analysis 10-20 DBiT RNA-seq and DBiT ATAC-seq, two TBD genes : crit, milestone, ADGC3_N_23, 2027-03-31, 0d </pre> </div> </div> <a name="ADGC4"></a> <!-- Start of ADGC4 Henry Gantt Chart--> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC4 Broad timeline</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC4 Broad [R01MH128366] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, year3_broad, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d click year3_broad href "https://docs.google.com/spreadsheets/d/1BwaO6rgn0o5nTulC2M6dQe5UMGUWEy-o/edit?gid=2037309850#gid=2037309850&range=D1:D16" section Aim 1 - Submit 100,000 scRNA-seq profiles per cell type (fastq) of 191 genes in 3 cell types : crit, milestone, ADGC4_Aim1_year4_item1, 2026-03-31, 0d - Submit image dataset of 120 TB (443 genes in 3 cells 5 million profiles) : crit, milestone, ADGC4_Aim1_year4_item2, 2026-03-31, 0d + Submit 100,000 scRNA-seq profiles per cell type (fastq) of 191 genes in 3 cell types : crit, milestone, ADGC4_Aim1_year4_E_3, 2026-03-31, 0d + Submit image dataset of 120 TB (443 genes in 3 cells 5 million profiles) : crit, milestone, ADGC4_Aim1_year4_E_4, 2026-03-31, 0d Submit remaining image datasets : crit, milestone, ADGC4_Aim1_year5_item1, 2027-03-31, 0d section Aim 2 - Submit 100,000 scRNA-seq profiles per cell type of 191 genes in 3 cell types (fastq) : crit, milestone, ADGC4_Aim2_year4_item1, 2026-03-31, 0d - Submit 50 TB of calcium imaging and MERFISH data : done, milestone, ADGC4_Aim2_year3_item1, 2025-03-31, 0d - Submit 5 TB of optical electrophysiology data - DATA QUALITY BEING ASSESSED : crit, milestone, ADGC4_Aim2_year3_item2, 2026-03-31, 0d - Submit 5 TB of optical electrophysiology data : crit, milestone, ADGC4_Aim2_year4_item2, 2026-03-31, 0d + Submit 100,000 scRNA-seq profiles per cell type of 191 genes in 3 cell types (fastq) : crit, milestone, ADGC4_Aim2_year4_E_9, 2026-03-31, 0d + Submit 50 TB of calcium imaging and MERFISH data : done, milestone, ADGC4_Aim2_year3_D_11, 2025-03-31, 0d + Submit 5 TB of optical electrophysiology data - DATA QUALITY BEING ASSESSED : crit, milestone, ADGC4_Aim2_year3_D_10, 2026-03-31, 0d + Submit 5 TB of optical electrophysiology data : crit, milestone, ADGC4_Aim2_year4_E_10, 2026-03-31, 0d Submit remaining optical electrophysiology data : crit, milestone, ADGC4_Aim2_year5_item1, 2027-03-31, 0d section Aim 3 - Submit RNA-seq profiles - ANALYSIS / SUBMISSION UNDERWAY : crit, milestone, ADGC4_Aim3_year3_item1, 2025-03-31, 0d - Submit RNA-seq profiles from >10,000 cells : crit, milestone, ADGC4_Aim3_year4_item1, 2026-03-31, 0d + Submit RNA-seq profiles - ANALYSIS / SUBMISSION UNDERWAY : crit, milestone, ADGC4_Aim3_year3_D_15, 2025-03-31, 0d + Submit RNA-seq profiles from >10,000 cells : crit, milestone, ADGC4_Aim3_year4_E_15, 2026-03-31, 0d Submit remaining RNA-seq profiles : crit, milestone, ADGC4_Aim3_year5_item1, 2027-03-31, 0d - Submit 10 TB of associated images to DRACC : crit, milestone, ADGC4_Aim3_year4_item2, 2026-03-31, 0d + Submit 10 TB of associated images to DRACC : crit, milestone, ADGC4_Aim3_year4_D_16, 2026-03-31, 0d Submit remaining morphology imaging : crit, milestone, ADGC4_Aim3_year5_item2, 2027-03-31, 0d </pre> </div> </div> <a name="ADGC5"></a> <!-- Start of ADGC5 Henry Gantt Chart--> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC5 Scripps/Broad timeline</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC5 Scripps/Broad [R01MH137042-01/-02] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, m1, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d section Scripps/Broad Reporting Year End Scripps/Broad Reporting Year 1 :milestone, year1_scripps, 2025-03-31, 0d End Scripps/Broad Reporting Year 2 :milestone, m1, 2026-03-31, 0d End Scripps/Broad Reporting Year 3 :milestone, m1, 2027-03-31, 0d click year1_scripps href "https://docs.google.com/spreadsheets/d/19RWN6-DjIyMpFV2JP4yY5Ta5Xfthieds/edit?gid=744607405#gid=744607405&range=C2:C15" section Aim 1 Generate multiomics data for 50 genes in 1 brain region at 1 time point : V_Y2t1, 2025-03-31,52w Submit L0/L1 data to DRACC (Restricted) 175 FASTQ for 75TB overall : crit, milestone, ADGC5_Aim1_year4_item1, 2026-03-31, 0d section Aim 2 Generate raw TIFF format and 3D swc files for 100 neurons on 3 genes : V_Y2t7, 2025-03-31,52w </pre> </div> </div> <a name="ADGC6"></a> <!-- Start of ADGC6 Henry Gantt Chart--> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC6 SING Timeline</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC6 Cross-Scale Interrogation of NPD Genes (SING) - PSU/JAX/UTSW/NYU [RM1MH138309] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, m1, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d section SING Reporting Year End SING Reporting Year 1 :milestone, year1_SING, 2025-12-31, 0d End SING Reporting Year 2 :milestone, m1, 2026-12-31, 0d click year1_SING href "https://docs.google.com/spreadsheets/d/1pw1muwglklo-gXrC5hadYjSqBjhZOKeh/edit?gid=1827916005#gid=1827916005&range=C2:E23" section Aim 1 DRACC data transfer of C57 control MERFISH : crit, milestone, ADGC6_D_8, 2025-09-30, 0d DRACC data transfer of first 5 KO mice MERFISH data : crit, milestone, ADGC6_E_7, 2025-12-31, 0d DRACC data transfer of 2025 Q4 and 20026 Q1-Q3 KO mice MERFISH data : crit, milestone, ADGC6_F_7, 2026-12-31, 0d DRACC data transfer of C57 control 10x Flex : crit, milestone, ADGC6_D_10, 2025-09-30, 0d DRACC data transfer of 10x Flex from 2025 and 2026Q1-Q2 : crit, milestone, ADGC6_F_10, 2026-12-31, 0d DRACC data transfer of C57 control L0 1TB, L1 0.5TB spatial txn : crit, milestone, ADGC6_Y2_B_4, 2026-03-31, 0d DRACC data transfer of 1st-4th KO L0 4TB, L1 2TB spatial txn : crit, milestone, ADGC6_Y2_C_5, 2026-07-01, 0d DRACC data transfer of 1st-4th scRNA-seq L0 0.8TB data, L1 0.4TB : crit, milestone, ADGC6_Y2_D_6, 2026-09-30, 0d DRACC data transfer of 5th-8th KO L0 4TB, L1 2TB spatial txn : crit, milestone, ADGC6_Y2_D_7, 2026-09-30, 0d DRACC data transfer of 5th-8th line scRNA-seq L0 0.8TB data, L1 0.4TB : crit, milestone, ADGC6_Y2_E_6, 2026-12-31, 0d DRACC data transfer of 9th - 12th KO L0 4TB, L1 2TB spatial txn : crit, milestone, ADGC6_Y2_E_7, 2026-12-31, 0d section Aim 2 DRACC data transfer of C57 control MRI and LSFM data : crit, milestone, ADGC6_D_16, 2025-09-30, 0d DRACC data transfer of first 5 KO mice MRI and LSFM data : crit, milestone, ADGC6_E_16, 2025-12-31, 0d DRACC data transfer of 2025 Q4 and 20026 Q1-Q3 KO mice MRI and LSFM data : crit, milestone, ADGC6_F_16, 2026-12-31, 0d DRACC data transfer of 1st-5th MRI L0 0.24TB data, L1 0.2TB, initial analysis 20 mouse brains : crit, milestone, ADGC6_Y2_B_11, 2026-03-31, 0d DRACC data transfer of 6th-10th MRI L0 0.5TB data, L1 0.5TB : crit, milestone, ADGC6_Y2_C_11, 2026-07-01, 0d DRACC data transfer of 6th-10th LSFM L1 5TB data, L2 0.5TB CCF mapped 1st-5th lines : crit, milestone, ADGC6_Y2_C_15, 2026-07-01, 0d DRACC data transfer of 11th-15th MRI L0 0.5TB data, L1 0.5TB : crit, milestone, ADGC6_Y2_D_11, 2026-09-30, 0d DRACC data transfer of 16th-20th MRI L0 0.5TB data, L1 0.5TB : crit, milestone, ADGC6_Y2_E_11, 2026-12-31, 0d DRACC data transfer of 16th-20th LSFM L1 5TB data, L2 0.5TB CCF mapped 11th-15th lines : crit, milestone, ADGC6_Y2_E_15, 2026-12-31, 0d section Aim 3 DRACC data transfer of C57 control behavioral data : crit, milestone, ADGC6_D_23, 2025-09-30, 0d DRACC data transfer of first 5 KO lines behavioral data : crit, milestone, ADGC6_E_23, 2025-12-31, 0d DRACC data transfer of 2025 Q4 and 20026 Q1-Q3 KO line behavioral data : crit, milestone, ADGC6_F_23, 2026-12-31, 0d DRACC data transfer of L0 Video, L1 tracking behavior from lines : crit, milestone, ADGC6_Y2_B_22, 2026-03-31, 0d DRACC data transfer of L0 Video, L1 tracking behavior from lines : crit, milestone, ADGC6_Y2_C_22, 2026-07-01, 0d DRACC data transfer of L0 Video, L1 tracking behavior from lines : crit, milestone, ADGC6_Y2_D_22, 2026-09-30, 0d DRACC data transfer of L0 Video, L1 tracking behavior from lines : crit, milestone, ADGC6_Y2_E_22, 2026-12-31, 0d </pre> </div> </div> <!-- Start of ADGC7 Henry Gantt Chart--> <a name="ADGC7"></a> <div class="cirm-page-title back-light-blue"><h5 class="cirm-page-title-text">ADGC7 WUSTL Timeline</h5></div> <div class="row"> <div class="col-md-12"> <pre class="mermaid"> gantt dateFormat YYYY-MM-DD axisFormat %Y-Q%q title ADGC7 Washington Univ. St Louis - WUSTL [RM1MH138313] section Grant Year - Start Grant Year 2 :milestone, m1, 2024-03-31, 0d Start Grant Year 3 :milestone, m1, 2025-03-31, 0d Start Grant Year 4 :milestone, m1, 2026-03-31, 0d Start Grant Year 5 :milestone, m1, 2027-03-31, 0d section WUSTL Reporting Year End WUSTL Reporting Year 1 :milestone, year1_wustl, 2025-12-31, 0d End WUSTL Reporting Year 2 :milestone, m1, 2026-12-31, 0d click year1_wustl href "https://docs.google.com/spreadsheets/d/1ae4bX4Ful2AWlqzeH_JOo4jFssmEsojd/edit?gid=1888128068#gid=1888128068&range=C2:E27" section Aim 1 L0, L1 Data from last quarter submitted, and 3 more lines collected : crit, milestone, ADGC7_E_12, 2025-12-31, 0d L0, L1 Data from last quarter submitted, and 4 more lines collected : crit, milestone, ADGC7_F_12, 2026-03-31, 0d L2, L3 from prior L0,L1 data submitted : crit, milestone, ADGC7_F_13, 2026-03-31, 0d L0, L1 Data from lines 1-2 submitted : crit, milestone, ADGC7_Y2_C_12, 2026-07-01, 0d L2, L3 from lines 1-2 submitted : crit, milestone, ADGC7_Y2_D_12, 2026-09-30, 0d L0, L1 Data from lines 3-5 submitted : crit, milestone, ADGC7_Y2_D_13, 2026-09-30, 0d L2, L3 from lines 3-5 submitted : crit, milestone, ADGC7_Y2_E_13, 2026-12-31, 0d L0, L1 Data from lines 6-10 submitted : crit, milestone, ADGC7_Y2_E_14, 2026-12-31, 0d %% snRNAseq collected for lines 15-30 and data submitted one quarter post collection, L2 and L3 data submitted 2 quarters post collection : crit, milestone, ADGC7_Y2_F_12, 2027-12-31, 0d %% L0, L1 Data from lines 11-14 submitted : crit, milestone, ADGC7_Y2_F_13, 2027-12-31, 0d %% L2, L3 from lines 6-10 submitted : crit, milestone, ADGC7_Y2_F_14, 2027-12-31, 0d section Aim 2 Home Cage Behavior L0-L1 Data to DRACC for lines 1-2 : crit, milestone, ADGC7_C_17, 2025-07-01, 0d Home Cage Behavior L3 Data to DRACC for lines 1-2 : crit, milestone, ADGC7_D_18, 2025-09-30, 0d Home Cage Behavior L4 Data to DRACC for lines 1-2 : crit, milestone, ADGC7_E_19, 2025-12-31, 0d Home Cage Behavior L0-L1 Data to DRACC for line 3-4 : crit, milestone, ADGC7_D_17, 2025-09-30, 0d Home Cage Behavior L3 Data to DRACC for lines 3-4 : crit, milestone, ADGC7_E_18, 2025-12-31, 0d %% Home Cage Behavior L4 Data to DRACC for lines 3-4 : crit, milestone, ADGC7_F_19, 2026-03-31, 0d Home Cage Behavior L4 Data to DRACC for lines 3-4: crit, milestone, ADGC7_Y2_B_19, 2026-03-31, 0d Home Cage Behavior L0-L1 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_E_17, 2025-12-31, 0d %% Home Cage Behavior L3 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_F_18, 2026-03-31, 0d Home Cage Behavior L3 Data to DRACC for lines 5-7: crit, milestone, ADGC7_Y2_B_18, 2026-03-31, 0d Home Cage Behavior L4 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_Y2_C_19, 2026-07-01, 0d Home Cage Behavior L0-L1 Data to DRACC for lines 8-12: crit, milestone, ADGC7_Y2_B_17, 2026-03-31, Home Cage Behavior L3 Data to DRACC for line 8-12 : crit, milestone, ADGC7_Y2_C_18, 2026-07-01, 0d Home Cage Behavior L4 Data to DRACC for lines 8-12 : crit, milestone, ADGC7_Y2_D_19, 2026-09-30, 0d Home Cage Behavior L0-L1 Data to DRACC for lines 13-16 : crit, milestone, ADGC7_Y2_C_17, 2026-07-01, 0d Home Cage Behavior L3 Data to DRACC for line 13-16 : crit, milestone, ADGC7_Y2_D_18, 2026-09-30, 0d Home Cage Behavior L4 Data to DRACC for lines 13-16 : crit, milestone, ADGC7_Y2_E_19, 2026-12-31, 0d Home Cage Behavior L0-L1 Data to DRACC for lines 17-22 : crit, milestone, ADGC7_Y2_D_17, 2026-09-30, 0d Home Cage Behavior L3 Data to DRACC for line 17-22 : crit, milestone, ADGC7_Y2_E_18, 2026-12-31, 0d %% Home Cage Behavior L4 Data to DRACC for lines 17-22 : crit, milestone, ADGC7_Y2_F_19, 2027-12-31, 0d Home Cage Behavior L0-L1 Data to DRACC for lines 23-27 : crit, milestone, ADGC7_Y2_E_17, 2026-12-31, 0d %% Home Cage Behavior L3 Data to DRACC for line 23-27 : crit, milestone, ADGC7_Y2_F_18, 2027-12-31, 0d %% Home Cage Behavior L0-L1 data to DRACC for lines 28-32 : crit, milestone, ADGC7_Y2_F_17, 2027-12-31, 0d IB & SI L0 Data to DRACC for lines 1-2 : crit, milestone, ADGC7_C_20, 2025-07-01, 0d IB & SI L1 & L3 Data to DRACC for lines 1-2 : crit, milestone, ADGC7_D_20, 2025-09-30, 0d IB & SI L4 Data to DRACC for lines 1-2 : crit, milestone, ADGC7_E_20, 2025-12-31, 0d IB & SI L0 Data to DRACC for lines 3-4 : crit, milestone, ADGC7_D_21, 2025-09-30, 0d IB & SI L1 & L3 Data to DRACC for line 3-4 : crit, milestone, ADGC7_E_21, 2025-12-31, 0d %% IB & SI L4 Data to DRACC for lines 3-4 : crit, milestone, ADGC7_F_21, 2026-03-31, 0d IB & SI L4 Data to DRACC for lines 3-4 : crit, milestone, ADGC7_Y2_B_20, 2026-03-31, 0d IB & SI L0 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_E_22, 2025-12-31, 0d %% IB & SI L1 & L3 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_F_22, 2026-03-31, 0d IB & SI L1 & L3 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_Y2_B_21, 2026-03-31, 0d IB & SI L4 Data to DRACC for lines 5-7 : crit, milestone, ADGC7_Y2_C_20, 2026-07-01, 0d IB & SI L0 Data to DRACC for lines 8-12 : crit, milestone, ADGC7_Y2_B_22, 2026-03-31, 0d IB & SI L1 & L3 Data to DRACC for line 8-12 : crit, milestone, ADGC7_Y2_C_21, 2026-07-01, 0d IB & SI L4 Data to DRACC for lines 8-12 : crit, milestone, ADGC7_Y2_D_20, 2026-09-30, 0d IB & SI L0 Data to DRACC for lines 13-16 : crit, milestone, ADGC7_Y2_C_22, 2026-07-01, 0d IB & SI L1 & L3 Data to DRACC for line 13-16 : crit, milestone, ADGC7_Y2_D_21, 2026-09-30, 0d IB & SI L4 Data to DRACC for lines 13-16 : crit, milestone, ADGC7_Y2_E_20, 2026-12-31, 0d IB & SI L0 Data to DRACC for lines 17-22 : crit, milestone, ADGC7_Y2_D_22, 2026-09-30, 0d IB & SI L1 & L3 Data to DRACC for line 17-22 : crit, milestone, ADGC7_Y2_E_21, 2026-12-31, 0d IB & SI L0 Data to DRACC for lines 23-27 : crit, milestone, ADGC7_Y2_E_22, 2026-12-31, 0d %% IB & SI L4 Data to DRACC for lines 17-22 : crit, milestone, ADGC7_Y2_F_20, 2027-12-31, 0d %% IB & SI L1 & L3 Data to DRACC for line 23-27 : crit, milestone, ADGC7_Y2_F_21, 2027-12-31, 0d %% IB & SI L0 Data to DRACC for lines 28-32 : crit, milestone, ADGC7_Y2_F_22, 2027-12-31, 0d section Aim 3 %% Imaging L0, L1 data collected for 3 lines : crit, milestone, ADGC7_D_27, 2025-09-30, 0d L0, L1 Data from last quarter submitted, and 4 more lines collected : crit, milestone, ADGC7_E_27, 2025-12-31, 0d %% L0, L1 Data from last quarter submitted, and 4 more lines collected : crit, milestone, ADGC7_F_27, 2026-03-31, 0d L2, L3 from prior L0,L1 data submitted : crit, milestone, ADGC7_F_28, 2026-03-31, 0d L0, L1 Data from lines 1-3 submitted : crit, milestone, ADGC7_Y2_B_27, 2026-03-31, 0d L2, L3 from lines 1-3 submitted : crit, milestone, ADGC7_Y2_C_27, 2026-07-01, 0d L0, L1 Data from lines 4-6 submitted : crit, milestone, ADGC7_Y2_C_28, 2026-07-01, 0d L2, L3 from lines 4-6 submitted : crit, milestone, ADGC7_Y2_D_28, 2026-09-30, 0d L0, L1 Data from lines 7-11 submitted : crit, milestone, ADGC7_Y2_D_29, 2026-09-30, 0d L2, L3 from lines 7-11 submitted : crit, milestone, ADGC7_Y2_E_29, 2026-12-31, 0d L0, L1 Data from lines 11-15 submitted : crit, milestone, ADGC7_Y2_E_30, 2026-12-31, 0d %% Spatial collected for lines 20-40 and data submitted one quarter post collection, L2 and L3 data submitted 2 quarters post collection : crit, milestone, ADGC7_Y2_F_28, 2027-12-31, 0d %% L0, L1 Data from lines 16-20 submitted : crit, milestone, ADGC7_Y2_F_29, 2027-12-31, 0d %% L2, L3 from lines 11-15 submitted : crit, milestone, ADGC7_Y2_F_30, 2027-12-31, 0d </pre> </div> </div> <!--#include virtual="${ROOT}inc/footer.html" -->