019256d07c6f791954ecb76e3e40a4da960098ef lrnassar Wed Mar 18 16:43:19 2026 -0700 Fixing small issues I noticed in commits, refs #37243 diff --git src/hg/htdocs/goldenPath/help/hgConvert.html src/hg/htdocs/goldenPath/help/hgConvert.html index 58d24052dcf..3a1fc2cef2e 100755 --- src/hg/htdocs/goldenPath/help/hgConvert.html +++ src/hg/htdocs/goldenPath/help/hgConvert.html @@ -1,147 +1,146 @@ -
An alignment between two DNA sequences maps every nucleotide in one sequence to a nucleotide in another sequence. By making and using whole-genome alignments, the UCSC Genome Browser always allowed users to "lift" genome annotations to another assembly (liftOver), in bulk, one track at a time. QuickLift is a tool that uses the same algorithm, but it maps (liftOver) annotations on demand, in real-time, for all visible tracks. Only the annotations in the currently visible region are lifted, so this is usually fast enough when browsing a genome. For example, QuickLift can be used to map annotations from hg38 or hg19 to any of the hundreds of new human high-quality genomes in GenArk (HPRC), with almost no additional delay. For instance, you can view GENCODE genes from hg38 on a T2T assembly like hs1, carrying over your visible tracks to the target genome assembly.
QuickLift functionality depends on the availability of alignment files (chains) that describe how sequences in one assembly correspond to another. The alignment files are currently made at UCSC, and if no alignment file is available for the assembly in which you're interested, please send a request to the genome mailing list, and we will attempt to provide you with one.
The source assembly is the assembly where the annotations come from, and the destination (target) assembly is the assembly you are converting to. To use QuickLift, follow these steps:
QuickLift tracks have a green left-side button bar in the Browser graphic (instead of the usual gray):
The Alignment Differences track displays liftOver differences using triangles and lines:
Mousing over a triangle displays the size base-pair (bp) difference and the type of alignment difference.
Clicking a triangle provides the source and target assembly genome positions, DNA sequence alignment, including the type of alignment difference with the bases within the currently visible browser region.
QuickLift does not support the following track formats:
wigToBigWig
utilitypslToBed
utilitybedToBigBed
utility